The reliability and validity of Turkish version of the night eating questionnaire in psychiatric outpatient population [Gece yeme anketi-türkçe formunun psikiyatrik ayaktan hasta popülasyonunda geçerlilik ve güvenilirlik çali{dotless}şmasi{dotless}]

Objective: The purpose of this study was to evaluate the reliability and validity of Turkish Version of the Night Eating Questionnaire (NEQ) in psychiatric out-patient population as a measure of severity of the night eating syn-drome (NES). Methods: We examined the factor structure, internal consistency and validity of the NEQ in Turkish. First, we translated NEQ into Turkish and than back-translation into English; correction and semantic adaptation and assessment of the understanding of the questionnaire. We made the diagnosis of NES according to psychiatric examination. We administered the NEQ in 433 patients and the re-test in 141 participants two weeks later. Result: The instrument showed satisfactory internal consistency with an overall Cronbach ? of 0.69. Intraclass correlation for the test re-test total score was 0.96. The ninety seven patients had NES with psychiatric examination. The area under ROC curve defined as 0,904. For cutt-of point of 18 in NEQ both sensitivity and spesificity were as 90.7% and 73.8%. The confirmatory factor analysis of the NEQ yielded a similar four factor solution as the original scale. Conclusions: We found that Turkish version of NEQ is valid and has good diagnostical performance, and high internal consistency

The prevalence and clinical features of the night eating syndrome in psychiatric out-patient population

Objective In this study we aimed to investigate the prevalance and clinical correlations of night eating syndrome (NES) in a sample of psychiatric outpatients. Method Four hundred thirthy three consecutive psychiatric out-patients older than 18 years were evaluated in the outpatient clinics using clinical interview according to the DSM-IV with regard to psychiatric diagnosis. Participants were also screened for presence of NES utilizing both clinical interview and self report based on Night Eating Questionnaire (NEQ) instruments. Sociodemographic and clinical features such as age, gender, education level, socioeconomic level and body mass index (BMI) were also recorded. The Body Shape Questionnaire (BSQ) and the Symptom Checklist-90 Revised (SCL-90R) were administered. Results Based on the proposed diagnostic criteria of the NES via utilizing clinical interview method, 97 (32 male, 65 female) of the sample met diagnostic criteria for NES. The point prevalence of NES was 22.4%. No statistically significant differences were found between the two groups in terms of age, gender, marital status, education and BMI. The patients with NES had higher NEQ, BSQ and SCL-90R subscale scores than patients without NES. Prevalance of depressive disorder, impulse control disorder, and nicotine dependency was higher among patients with NES. No differences were found with regard to the medication (antipsychotics, antidepressants and mood stabilizers). Conclusion Night eating syndrome is prevalent among psychiatric outpatients and associated with depression, impulse control disorder, and nicotine dependency. Body dissatisfaction and higher symptom severity are also other risk factors for the development of NES. © 2014 Elsevier Inc

Antistreptococcal Response is Exaggerated in Children with Familial Mediterranean Fever

Familial Mediterranean fever (FMF) is an autosomal recessive disorder. Although the pathogenesis of the disease is not yet completely understood, enhanced acute-phase responsiveness is considered to be one of the most important mechanisms. The presence of high levels of antistreptolysin O (ASO) antibodies and streptococcus-associated diseases, such as acute poststreptococcal glomerulonephritis (AGN) and acute rheumatic fever (ARF), has been reported in patients with FMF. In order to better understand the effect of FMF on antistreptococcal antibody response, we measured ASO and antideoxyribonuclease B (anti-DNAse B) levels in patients with FMF and compared them with those in healthy controls. The study consisted of two parts. In the first step, antistreptococcal antibody levels were analysed in 44 patients with FMF and 165 healthy children who had no history or clinical evidence of upper respiratory tract infection (URTI) for the last 4 months. In the second step, antistreptococcal antibody levels were measured in 15 patients with FMF and 22 healthy controls in response to documented group A β-haemolytic streptococcal pharyngitis. In the first part of the study, ASO and anti-DNAse B levels in patients with FMF were found to be significantly higher than those in healthy controls (P<0.001). In the second part, ASO and anti-DNAse B titres were found to be significantly higher in patients with FMF than in controls (P<0.001 and <0.05, respectively) 4 weeks after a positive throat culture. We concluded that patients with FMF have an exaggerated response to streptococcal antigens and might be prone to poststreptococcal non-suppurative complications, such as ARF