83 research outputs found
N′-[(2Z)-3-Allyl-4-oxo-1,3-thiazolidin-2-ylidene]-5-fluoro-3-phenyl-1H-indole-2-carbohydrazide
In the title compound, C21H17FN4O2S, the planar indole fused-ring [maximum deviation 0.009 (1) Å] makes dihedral angles of 54.75 (9) and 14.90 (9)°, respectively, with the phenyl ring and the dihydrothiazolyl ring. The –CH2CH=CH2 substituent is disordered over two positions in a 0.51 (1):0.49 (1) ratio. An intramolecular N—H⋯S hydrogen bond generates an S(5) ring motif. The two independent molecules are linked into a dimer by two N—H⋯O hydrogen bonds, forming an R
2
2(10) ring motif. The crystal structure features intermolecular C—H⋯π and π–π stacking [centroid–centroid distance = 3.679 (1) Å] interactions. C—H⋯O and C—H⋯F interactions are also present
2-[2-(2,6-Dichloroanilino)phenyl]-N′-(4-propylcyclohexylidene)acetohydrazide
The asymmetric unit of the title compound, C23H27Cl2N3O, contains two crystallographically independent molecules in which the dihedral angles between the benzene rings are 70.1 (3) and 63.8 (3)°. In each molecule an intramolecular N—H⋯O hydrogen bond generates an S(7) ring. The atoms of the propyl grouping of one molecule are disordered over two orientations with occupancies of 0.666 (6) and 0.334 (6). The crystal structure is stabilized by N—H⋯O and C—H⋯O hydrogen-bonding interactions
5-Fluoro-N′-[(E)-4-methoxybenzylidene]-3-phenyl-1H-indole-2-carbohydrazide
In the title molecule, C23H18FN3O2, the mean plane of the indole system forms dihedral angles of 44.23 (8) and 14.54 (7)°, respectively, with the phenyl and benzene rings. In the crystal, intermolecular N—H⋯O hydrogen bonds link molecules into two-layer ribbons extended along the b axis. The crystal packing also exhibits weak intermolecular C—H⋯O, C—H⋯F and C—H⋯π interactions
4-{3-[Hydroxy(phenyl)methyl]-5-thioxo-4,5-dihydro-1H-1,2,4-triazol-4-yl}benzenesulfonamide
In the title compound, C15H14N4O3S2, the hydroxy group is disordered over two positions with occupancies of 0.619 (5) and 0.381 (5). The benzene ring attached to the heterocycle makes a dihedral angle of 86.92 (9)° with respect to the best plane through the five-membered ring. The crystal packing is stabilized by intermolecular O—H⋯O, N—H⋯S, N—H⋯N, C—H⋯O and C—H⋯N hydrogen bonds, and N—H⋯π and C—H⋯π interactions
5-Chloro-4′-ethyl-3H-spiro[1,3-benzothiazole-2,1′-cyclohexane]
In the title compound, C14H18ClNS, the 2,3-dihydro-1,3-thiazole ring adopts an envelope with the S,N-bound C atom at the flap and the cyclohexane ring adopts a chair conformation. In the crystal, N—H⋯S hydrogen bonds with C(5) motifs connect the molecules into chains parallel to the c axis
New 4-arylhydrazono-5(4H)-isoxazolone derivatives as possible antibacterial and anticonvulsant agents
Synthesis and anticonvulsant activity of new 3-[(2-furyl)carbonyl] amino-4-thiazolidinone and 2-[(2-furyl)carbonyl]hydrazono-4-thiazoline derivatives
Synthesis, characterization and biological evaluation of new benzylidenebenzohyd razides and 2,5-disubstituted 2,3-dihydro-1,3,4-oxadiazoles
Synthesis and anticonvulsant activity of new 4-thiazolidone and 4-thiazoline derivatives
Synthesis and antimicrobial activity of new tetrahydro-2H-1,3,5-thiadizine-2-thione derivatives
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