82 research outputs found
El Centro de Estudios de la América Colonial a lo largo del 2017
Se presenta en este texto un breve repaso a las actividades y publicaciones que el Centro de Estudios de la América Colonial ( CEAC) ha realizado durante el año 2017.In this document, it's presented all the activities and publications that the Colonial American Center of studies has done along 2017
Influence of reproduction on stable isotope ratios: nitrogen and carbon isotope discrimination between mothers, foetuses, and milk in the fin whale, a capital breeder
In mammals, the influence of gestation and lactation on the tissue stable-isotope ratios of females, fetuses, and milk remains poorly understood. Here we investigate the incidence of these events on δ13C and δ15N values in fin whales sampled off northwestern Spain between 1983 and 1985. The effect of gestation on tissue stable-isotope ratios was examined in the muscle of pregnant females (n = 13) and their fetuses (n = 10) and that of lactation in the muscle of nursing females (n = 21) and their milk (n = 25). Results suggest that fetuses are enriched compared to their mothers in both 15N (Δ15N = 1.5 ) and 13C (Δ13C =1.1 ), while, compared to muscle, milk is enriched in 15N (Δ15N = 0.3 ) but depleted in 13C (Δ13C = −0.62 ). This pattern is consistent with that previously observed for other species that, like the fin whale, rely on endogenous energy during reproduction, and it substantiates a general difference in the physiological processing of nitrogen and carbon balances between income and capital breeders. These findings are relevant to the understanding of the energetic balance of mammals during gestation and lactation and are central when inferences on trophic ecology are drawn from isotopic values of reproductive females
Discrimination of stable isotopes in fin whale tissues and application to diet assessment in cetaceans
RATIONALE In stable isotope research, the use of accurate, species‐specific diet‐tissue discrimination factors (i.e., Δ13C and Δ15N) is central to the estimation of trophic position relative to primary consumers and to the identification of the dietary sources of an individual. Previous research suggested that the diet of fin whales from the waters off northwestern Spain is overwhelmingly based on krill, thus permitting reliable calculation of discrimination values in this wild population. METHODS After confirming that the stable isotope ratios (δ13C and δ15N values) in muscle from 65 aged fin whales remained constant through age classes (4-65 years), the signatures were determined in muscle, bone protein, skin, liver, kidney, baleen plates and brain, as well as food (krill), from a subset of individuals to calculate discrimination factors. Signatures were determined by means of elemental analysis isotope ratio mass spectrometry (EA‐IRMS) using a ThermoFinnigan Flash 1112. RESULTS The isotopic values remained constant regardless of age. The mean Δ15N values between krill and whale tissues ranged from 2.04 in bone protein to 4.27¿ in brain, and those of Δ13C ranged from 1.28 in skin to 3.11¿ in bone protein. This variation was consistent with that found in other groups of mammals, and is attributed to variation in tissue composition and physiology. CONCLUSIONS Because discrimination factors are relatively constant between taxonomically close species, the results here obtained may be reliably extrapolated to other cetaceans to improve dietary reconstructions. The skin discrimination factors are of particular relevance to monitoring diet through biopsies or other non‐destructive sampling methods. The large difference in bone protein discrimination factors from those of other tissues should be taken into consideration when bone collagen is used to determine trophic level or to assess diet in paleodietary isotopic reconstructions
Las veladas de San Petersburgo : política y literatura en el pensamiento contrarrevolucionario de Joseph de Maistre
Isotopic evidence of limited exchange between Mediterranean and eastern North Atlantic fin whales
RATIONALE The relationship between stocks of fin whales inhabiting the temperate eastern North Atlantic and the Mediterranean Sea is subject to controversy. The use of chemical markers facilitates an alternative insight into population structure and potential borders between stocks because the two areas present dissimilar isotopic baselines. METHODS Baleen plates, composed of inert tissue that keeps a permanent chronological record of the isotopic value of body circulating fluids, were used to investigate connectivity and boundaries between the stocks. Values were determined by continuous flow isotope ratio mass spectrometry. RESULTS Stable isotopes confirm that, while the two subpopulations generally forage in well‐differentiated grounds, some individuals with characteristic Atlantic values do penetrate into the Mediterranean Sea up to the northernmost latitudes of the region. As a consequence, the border between the two putative subpopulations may be not as definite as previous acoustic investigations suggested. The discriminant function obtained in this study may assist researchers to use baleen plate isotopic data to assign the origin of fin whales of uncertain provenance. CONCLUSIONS This study strengthens the stock subdivision currently accepted for management and conservation while recognizes a low level of exchange between the Mediterranean and temperate eastern North Atlantic subdivisions
Trade synchronization in the World Trade Web
In March 2008, the bankruptcy of Lehman Brothers marked for many the beginning of the global crisis. In an increasingly globalized world, the financial crisis spread relentlessly. Recent theories of financial fragility link globalization with economic cycles, i.e. when local crises coincide with bad credit regulation and failures in international monetary arrangements. The globalization process in recent years has been accelerated due to to the increase of international trade. Here we analyze how economic cycles can spread worldwide over the global trade network (WTW). We use the WTW network structure to simulate a network of Integrate-and-Fire oscillators for two different years, 1980 and 2000. The results reinforce the idea that globalization accelerates the global synchronization process
Enhancing drones for law enforcement and capacity monitoring at open large events
Police tasks related with law enforcement and citizen protection have gained a very useful asset in drones. Crowded demonstrations, large sporting events, or summer festivals are typical situations when aerial surveillance is necessary. The eyes in the sky are moving from the use of manned helicopters to drones due to costs, environmental impact, and discretion, resulting in local, regional, and national police forces possessing specific units equipped with drones. In this paper, we describe an artificial intelligence solution developed for the Castelldefels local police (Barcelona, Spain) to enhance the capabilities of drones used for the surveillance of large events. In particular, we propose a novel methodology for the efficient integration of deep learning algorithms in drone avionics. This integration improves the capabilities of the drone for tasks related with capacity control. These tasks have been very relevant during the pandemic and beyond. Controlling the number of persons in an open area is crucial when the expected crowd might exceed the capacity of the area and put humans in danger. The new methodology proposes an efficient and accurate execution of deep learning algorithms, which are usually highly demanding for computation resources. Results show that the state-of-the-art artificial intelligence models are too slow when utilised in the drone standard equipment. These models lose accuracy when images are taken at altitudes above 30 metres. With our new methodology, these two drawbacks can be overcome and results with good accuracy (96% correct segmentation and between 20% and 35% mean average proportional error) can be obtained in less than 20 s.This research was partially funded by the AGAUR research agency of Catalonia under
grant number 2020PANDE00141 and by the Ministry of Science and Education of Spain under grant
number PID2020-116377RB-C21.Peer ReviewedPostprint (published version
Evaluation of metabolic changes in acute intermittent porphyria patients by targeted metabolomics
Acute intermittent porphyria (AIP) is an inherited rare hepatic disorder due to mutations within the hydroxymethylbilane gene. AIP patients with active disease overproduce aminolevulinic acid (ALA) and porphobilinogen (PBG) in the liver which are exported inducing severe neurological attacks. Different hepatic metabolic abnormalities have been described to be associated with this condition. The goal of this research was to explore the metabolome of symptomatic AIP patients by state-of-the art liquid chromatography-tandem mass spectrometry (LC-MS/MS). A case versus control study including 18 symptomatic AIP patients and 33 healthy controls was performed. Plasmatic levels of 51 metabolites and 16 ratios belonging to four metabolic pathways were determined. The results showed that the AIP patients presented significant changes in the two main areas of the metabolome under study: (a) the tryptophan/kynurenine pathway with an increase of tryptophan in plasma together with increase of the kynurenine/tryptophan ratio; and (b) changes in the tricarboxylic acid cycle (TCA) including increase of succinic acid and decrease of the fumaric acid/succinic acid ratio. We performed a complementary in vitro study adding ALA to hepatocytes media that showed some of the effects on the TCA cycle were parallel to those observed in vivo. Our study confirms in plasma previous results obtained in urine showing that AIP patients present a moderate increase of the kynurenine/tryptophan ratio possibly associated with inflammation. In addition, it also reports changes in the mitochondrial TCA cycle that, despite requiring further research, could be associated with an energy misbalance due to sustained overproduction of heme-precursors in the liver.This research was funded by Instituto de Salud Carlos III FEDER (grant number PI14/00147), Generalitat de Catalunya (research team grant number 2014SGR692) and Spanish Health National System (contract number CPII16/00027 for Oscar J Pozo).Peer ReviewedPostprint (published version
Emergence of assortative mixing between clusters of cultured neurons
The analysis of the activity of neuronal cultures is considered to be a good proxy of the functional connectivity of in vivo neuronal tissues. Thus, the functional complex network inferred from activity patterns is a promising way to unravel the interplay between structure and functionality of neuronal systems. Here, we monitor the spontaneous self-sustained dynamics in neuronal cultures formed by interconnected aggregates of neurons (clusters). Dynamics is characterized by the fast activation of groups of clusters in sequences termed bursts. The analysis of the time delays between clusters' activations within the bursts allows the reconstruction of the directed functional connectivity of the network. We propose a method to statistically infer this connectivity and analyze the resulting properties of the associated complex networks. Surprisingly enough, in contrast to what has been reported for many biological networks, the clustered neuronal cultures present assortative mixing connectivity values, meaning that there is a preference for clusters to link to other clusters that share similar functional connectivity, as well as a rich-club core, which shapes a"connectivity backbone" in the network. These results point out that the grouping of neurons and the assortative connectivity between clusters are intrinsic survival mechanisms of the culture
Topographical variation in lipid content and morphological structure of the blubber in the striped dolphin
We investigate stratification patterns and topographical variations in the blubber of the striped dolphin (Stenella coeruleoalba) to gain insights into its regionally-specific functions. We collected blubber from 10 stranded striped dolphins (5 females and 5 males) from the eastern coast of Spain in 2007-2009, at 11 body positions. Histological measurements (adipocyte number and area) and blubber lipid content were analysed for each position. Histological measurements revealed stratification of blubber into outer, middle, and inner layers. Both the adipocyte number and area were largest in the middle layer. The adipocyte number was higher in the outer than the inner layer, whereas the adipocyte area was higher in the inner than the outer layer. The ventral anterior position did not follow this pattern, likely due to its proximity to the acoustic blubber, which is known to have a different biochemical composition. The stratification in morphological blubber characteristics most likely reflects functional differences. The outer layer may provide structural support and act as a mechanical barrier with a minor role in energy storage. The middle layer may be responsible for thermoregulation, and the inner layer could be responsible for energy mobilization, which is favoured by its proximity to the body core and a higher vascularization. In addition, an increasing gradient from dorsal to ventral positions was observed in the mean number of adipocytes and lipid content, with the exception of the caudal region. Although both ventral and dorsal blubber can have insulator and buoyancy functions, the ventral blubber may mainly serve as an energy reserve
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