173 research outputs found

    Basketball game-related statistics that discriminate between teams season-long success

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    The aim of the present study was to identify the game-related statistics that discriminate between season-long successful and unsuccessful basketball teams participating in the Spanish Basketball League (LEB1). The sample included all 145 average records per season from the 870 games played between the 2000-2001 and the 2005-2006 regular seasons. The following game-related statistics were gathered from the official box scores of the Spanish Basketball Federation: 2- and 3-point field-goal attempts (both successful and unsuccessful), free-throws (both successful and unsuccessful), defensive and offensive rebounds, assists, steals, turnovers, blocks (both made and received), and fouls (both committed and received). To control for season variability, all results were normalized to minutes played each season and then converted to z-scores. The results allowed discrimination between best and worst teams' performances through the following game-related statistics: assists (SC=0.47), steals (SC=0.34), and blocks (SC=0.30). The function obtained correctly classified 82.4% of the cases. In conclusion, season-long performance may be supported by players' and teams' passing skills and defensive preparation

    U(1) textures and Lepton Flavor Violation

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    U(1) family symmetries have led to successful predictions of the fermion mass spectrum and the mixing angles of the hadronic sector. In the context of the supersymmetric unified theories, they further imply a non-trivial mass structure for the scalar partners, giving rise to new sources of flavor violation. In the present work, lepton flavor non-conserving processes are examined in the context of the minimal supersymmetric standard model augmented by a U(1)-family symmetry. We calculate the mixing effects on the \mu-> e\gamma and \tau -> \mu\gamma rare decays. All supersymmetric scalar masses involved in the processes are determined at low energies using two loop renormalization group analysis and threshold corrections. Further, various novel effects are considered and found to have important impact on the branching ratios. Thus, a rather interesting result is that when the see-saw mechanism is applied in the (12 X 12)-sneutrino mass matrix, the mixing effects of the Dirac matrix in the effective light sneutrino sector are canceled at first order. In this class of models and for the case that soft term mixing is already present at the GUT scale, tau -> \mu \gamma decays are mostly expected to arise at rates significantly smaller than the current experimental limits. On the other hand, the \mu \ra e \gamma rare decays impose important bounds on the model parameters, particularly on the supersymmetric scalar mass spectrum. In the absence of soft term mixing at high energies, the predicted branching ratios for rare decays are, as expected, well below the experimental bounds.Comment: 24p, 10 figures, version to appear in Phys. Rev.

    "The trauma of competition": the entry of Air Products Inc. into the industrial gases business in Britain and continental Europe 1947-1970

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    The British Oxygen Company (BOC) had a virtual monopoly on the supply of industrial gases (e.g. oxygen and acetylene) on the British market through the 1950s, when it was finally challenged by an American-based company, Air Products. Air Products Limited (APL) was able to undercut BOCs position, overcoming high barriers to entry to gain significant market share in this sector, which shares some features of network industries. Factors in this success included conditions imposed by the Board of Trade, APL’s innovations, BOC’s slow response, and favourable market conditions. APL’s success had implications for the internationalisation of the industrial gases industry

    Clinical Validation of a 3-Dimensional Ultrafast Cardiac Magnetic Resonance Protocol Including Single Breath-Hold 3-Dimensional Sequences

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    Objectives: This study sought to clinically validate a novel 3-dimensional (3D) ultrafast cardiac magnetic resonance (CMR) protocol including cine (anatomy and function) and late gadolinium enhancement (LGE), each in a single breath-hold. Background: CMR is the reference tool for cardiac imaging but is time-consuming. Methods: A protocol comprising isotropic 3D cine (Enhanced sensitivity encoding [SENSE] by Static Outer volume Subtraction [ESSOS]) and isotropic 3D LGE sequences was compared with a standard cine+LGE protocol in a prospective study of 107 patients (age 58 ± 11 years; 24% female). Left ventricular (LV) mass, volumes, and LV and right ventricular (RV) ejection fraction (LVEF, RVEF) were assessed by 3D ESSOS and 2D cine CMR. LGE (% LV) was assessed using 3D and 2D sequences. Results: Three-dimensional and LGE acquisitions lasted 24 and 22 s, respectively. Three-dimensional and LGE images were of good quality and allowed quantification in all cases. Mean LVEF by 3D and 2D CMR were 51 ± 12% and 52 ± 12%, respectively, with excellent intermethod agreement (intraclass correlation coefficient [ICC]: 0.96; 95% confidence interval [CI]: 0.94 to 0.97) and insignificant bias. Mean RVEF 3D and 2D CMR were 60.4 ± 5.4% and 59.7 ± 5.2%, respectively, with acceptable intermethod agreement (ICC: 0.73; 95% CI: 0.63 to 0.81) and insignificant bias. Both 2D and 3D LGE showed excellent agreement, and intraobserver and interobserver agreement were excellent for 3D LGE. Conclusions: ESSOS single breath-hold 3D CMR allows accurate assessment of heart anatomy and function. Combining ESSOS with 3D LGE allows complete cardiac examination in less than 1 min of acquisition time. This protocol expands the indication for CMR, reduces costs, and increases patient comfort. (J Am Coll Cardiol Img 2021;14:1742–1754)Funding included Instituto de Salud Carlos III (ISCIII) and the European Regional Development Fund (ERDF) Grants DTS17/00136 to Dr. Ibáñez and PI19/01704 to Dr. Fernandez-Jimenez; Spanish Society of Cardiology Translational Research Grant 2016 to Dr. Ibáñez; European Research Council ERC-CoG 819775-MATRIX to Dr. Ibáñez; Comunidad de Madrid S2017/BMD-3867-RENIM-CM to Drs. Desco and Ibáñez; and Ministerio de Ciencia e Innovación (MICINN) RETOS2019-107332RB-I00 to Dr. Ibáñez. Dr. Fernandez-Jimenez received funding from the European Union Horizon 2020 research and innovation programme under Marie Sklodowska-Curie Hrant Agreement No. 707642. The CNIC is supported by the ISCIII, the MICINN, and the Pro CNIC Foundation. Drs. Fernandez-Jimenez, Nothnagel, Fuster, Ibáñez, and Javier Sánchez-González are inventors of a joint patent (Philips/CNIC) for the new cine imaging method here described and validated/protected under the IP #2014P00960EP. Drs. Nothnagel, Kouwenhoven, Clemence, and Javier Sánchez-González are Philips employees. All other authors have reported that they have no relationships relevant to the contents of this paper to disclose

    B -> X_s gamma in Supersymmetry with Explicit CP Violation

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    We discuss B -> X_s gamma decay in both constrained and unconstrained supersymmetric models with explicit CP violation within the minimal flavor violation scheme by including tan(beta) -enhanced large contributions beyond the leading order. In this analysis, we take into account the relevant cosmological and collider bounds, as well as electric dipole moment constraints. In the unconstrained model, there are portions of the parameter space yielding a large CP asymmetry at leading order (LO). In these regions, we find that the CP phases satisfy certain sum rules, e.g., the sum of the phases of the \mu parameter and the stop trilinear coupling centralize around \pi with a width determined by the experimental bounds. In addition, at large values of tan(beta), the sign of the CP asymmetry tracks the sign of the gluino mass, and the CP asymmetry is significantly larger than the LO prediction. In the constrained minimal supersymmetric standard model based on minimal supergravity, we find that the decay rate is sensitive to the phase of the universal trilinear coupling. This sensitivity decreases at large values of the universal gauino mass. We also show that for a given set of the mass parameters, there exists a threshold value of the phase of the universal trilinear coupling which grows with tan(beta) and beyond which the experimental bounds are satisfied. In both supersymmetric scenarios, the allowed ranges of the CP phases are wide enough to have phenomenological consequences.Comment: 25 pages, 11 figures. Added references, made minor changes in the text; journal versio

    Direct Detection of Dark Matter in the MSSM with Non-Universal Higgs Masses

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    We calculate dark matter scattering rates in the minimal supersymmetric extension of the Standard Model (MSSM), allowing the soft supersymmetry-breaking masses of the Higgs multiplets, m_{1,2}, to be non-universal (NUHM). Compared with the constrained MSSM (CMSSM) in which m_{1,2} are required to be equal to the soft supersymmetry-breaking masses m_0 of the squark and slepton masses, we find that the elastic scattering cross sections may be up to two orders of magnitude larger than values in the CMSSM for similar LSP masses. We find the following preferred ranges for the spin-independent cross section: 10^{-6} pb \ga \sigma_{SI} \ga 10^{-10} pb, and for the spin-dependent cross section: 10^{-3} pb \ga \sigma_{SD}, with the lower bound on \sigma_{SI} dependent on using the putative constraint from the muon anomalous magnetic moment. We stress the importance of incorporating accelerator and dark matter constraints in restricting the NUHM parameter space, and also of requiring that no undesirable vacuum appear below the GUT scale. In particular, values of the spin-independent cross section another order of magnitude larger would appear to be allowed, for small \tan \beta, if the GUT vacuum stability requirement were relaxed, and much lower cross-section values would be permitted if the muon anomalous magnetic moment constraint were dropped.Comment: 30 pages LaTeX, 40 eps figure

    BRIVA-LIFE–A multicenter retrospective study of the long-term use of brivaracetam in clinical practice

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    Objectives: Evaluate long-term effectiveness and tolerability of brivaracetam in clinical practice in patients with focal epilepsy. Materials and Methods: This was a multicenter retrospective study. Patients aged =16 years were started on brivaracetam from November 2016 to June 2017 and followed over 1 year. Data were obtained from medical records at 3, 6 and 12 months after treatment initiation for evaluation of safety- and seizure-related outcomes. Results: A total of 575 patients were included in analyses; most had been treated with =4 lifetime antiepileptic drugs. Target dosage was achieved by 30.6% of patients on the first day. Analysis of primary variables at 12 months revealed that mean reduction in seizure frequency was 36.0%, 39.7% of patients were =50% responders and 17.5% were seizure-free. Seizure-freedom was achieved by 37.5% of patients aged =65 years. Incidence of adverse events (AEs) and psychiatric AEs (PAEs) was 39.8% and 14.3%, respectively, and discontinuation due to these was 8.9% and 3.7%, respectively. Somnolence, irritability, and dizziness were the most frequently reported AEs. At baseline, 228 (39.7%) patients were being treated with levetiracetam; most switched to brivaracetam (dose ratio 1:10-15). Among those who switched because of PAEs (n = 53), 9 (17%) reported PAEs on brivaracetam, and 3 (5.7%) discontinued because of PAEs. Tolerability was not highly affected among patients with learning disability or psychiatric comorbidity. Conclusions: In a large population of patients with predominantly drug-resistant epilepsy, brivaracetam was effective and well-tolerated; no unexpected AEs occurred over 1 year, and the incidence of PAEs was lower compared with levetiracetam
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