Comparative Evaluation of Lactulose and Bisacodyl in the Management of Chronic Constipation: Efficacy, Safety, and Patient Preferences

Chronic constipation is a common gastrointestinal disorder, and its management often requires long-term use of laxatives. This review addresses the differences between two commonly used laxatives, lactulose and bisacodyl. The efficacy, side effect profiles, tolerance development, use in special populations, drug interactions, contraindications, and impacts on patient compliance and quality of life of these two laxatives are compared. Both lactulose and bisacodyl are effective in improving bowel movements and are widely used in clinical practice. However, lactulose might present a more favorable profile for certain patient populations when considering factors such as side effect profile, patient compliance, quality of life, and cost-effectiveness. Primary care physicians should consider these aspects when choosing the most appropriate treatment option for their patients, always considering individual patient characteristics and preferences

Stress behaviours of viscoelastic flow around square cylinder

In this study, it is aimed the numerically investigation of the flow of liner PTT (Phan-Thien-Tanner) fluid, which is a viscoelastic fluid model over limited square obstacle by finite volume method. The finite volume method has been used for simultaneous solution of continuity, momentum and fluid model equations with appropriate boundary conditions. The effects of the inertia in terms of Reynolds number, Re, (0 < Re < 20) and the of elasticity in terms of Weissenberg number, We, (1 < We < 15) of PTT flow on vertical and shear stress areas are examined in detail

Stress behavioursof viscoelastic flowaround square cylinder

In this study, it is aimed the numerically investigation of the flow of liner PTT (Phan-Thien-Tanner) fluid, which is a viscoelastic fluid model over limited square obstacle by finite volume method. The finite volume method has been used for simultaneous solution of continuity, momentum and fluid model equations with appropriate boundary conditions. The effects of the inertia in terms of Reynolds number, Re, (0 < Re < 20) and the of elasticity in terms of Weissenberg number, We, (1 < We < 15) of PTT flow on vertical and shear stress areas are examined in detail