Prognostic Value of Inflammation Parameters in Patients With Non-ST Elevation Acute Coronary Syndromes

Inflammation parameters can predict the severity of coronary artery disease and predict long-term mortality. However, there is no study in which these parameters were evaluated together. We compared the prognostic values of inflammation parameters in predicting long-term mortality in patients with non-ST elevation acute coronary syndrome (NSTE-ACS). Consecutive patients with NSTE-ACS (n = 170) were included in the study. Monocyte/high-density lipoprotein cholesterol (HDL-C) ratio (MHR), lymphocyte/monocyte ratio (LMR), neutrophil/lymphocyte ratio (NLR), platelet/lymphocyte ratio (PLR), total cholesterol/HDL-C ratio (TC/HDL-C), triglyceride /HDL-C ratio (TG/HDL-C), total antioxidant status (TAS), total oxidant status (TOS), oxidative stress index, and ischemia-modified albumin (IMA) were measured. Total antioxidant status and TOS variables were significant independent predictors of mortality. When 1.17 value is taken as a cutoff point of TAS values, the sensitivity (70.0%) and specificity (77.39%) values calculated for this value indicate that TAS variable has a predictive value on mortality. Monocyte/high-density lipoprotein cholesterol ratio, LMR, NLR, PLR, TC/HDL-C, TG/HDL-C, TOS, and IMA levels could not be used alone in the diagnosis, severity assessment, and predicting future mortality of NSTE-ACS. Only TAS levels had a predictive value on mortality. © The Author(s) 2020

Sirozlu hastalarda otonom nöropati varlığının renal kan akımı üzerindeki etkisi

Karaciğer sirozlu hastalarda sıklıkla sistemik, splanknik ve renal dolaşımda çeşitli hemodinamik değişiklikler mevcuttur. Bu hemodinamik değişiklikler özellikle ileri evre sirozu olan hastalarda daha belirgin olmaktadır. Biz çalışmamızda sirozlu hastalarda otonom nöropatinin (ON) mevcudiyetinin renal kan akımı üzerindeki etkilerinin araştırmayı amaçladık. Çalışmaya 59 karaciğer sirozlu hasta ve 45 sağlıklı kontrol alındı. Tüm hastaların ve kontrol grubunun her iki böbrek boyutları ve parankim kalınlıkları ölçüldü. Renal vasküler rezistans indeksleri (Rİ) sağ ve sol böbrekten doppler ultrasonografi ile değerlendirildi ve hastalara ON testleri yapıldı. Sirotik hastalar ile kontrol grubu karşılaştırıldığında, sırası ile her iki böbrek boyutlarında ve parankim kalınlığında fark yok iken, her iki böbrekten ölçülen renal arter (sağ böbrekten 0,70±0,06 , 0,61±0,03 ve sol böbrekten 0,69±0,06 , 0,61±0,03) ve interlober arter Rİ (sağ böbrekten 0,65±0,06 , 0,57±0,04 ve sol böbrekten 0,66±0,06 , 0,56±0,03) arasında anlamlı fark vardı (p<0.000). Sirotik hastalar Child-Pugh sınıflamasına göre kendi aralarında da tanımlanan ölçümler açısından karşılaştırıldı ve Rİ, Child-Pugh B ve C’de, Child-Pugh A’dan daha yüksek olmasına rağmen aralarında istatistiksel bir fark yoktu. Sadece Child-Pugh A ve B grubunda sağ renal arter Rİ arasında anlamlı bir fark saptandı (p=0.021). Erken evre siroz (Child-Pugh A) ve ileri siroz (Child-Pugh B ve C) karşılaştırıldığında sağ renal arter Rİ ileri evre siroz grubunda istatistiksel olarak anlamlı derecede daha yüksek bulundu (p=0,041). Çalışmaya alınan 59 sirotik hastanın 37’sinde ON tespit edildi. Child-Pugh evresi arttıkça ON sıklığı anlamlı derecede artmakta idi (p0,05). Yine benzer olarak asiti olan ve olmayan hastalar arasında da bütün parametreler arasında istatistiksel olarak anlamlı bir fark yoktu (p>0,05). Bizim çalışmamızda sirotik hastalarda ON sıklığı daha önce yapılan çalışmalarda bildirilene benzer olarak bulundu. Renal arter ve interlober arter Rİ sirotik hastalarda kontrollere göre artmıştı. Ayrıca ON’si olan ve olmayan sirotik hastalarda, renal arter ve interlober arter Rİ açısından fark yoktu. ON varlığının renal hemodinamikler üzerine herhangi bir etkisi tesbit edilmedi

Evaluation of John Dewey in Terms of Articles Reflected in Periodicals in Turkey

The aim of this research is to make a general evaluation of the articles about John Dewey published in the period of Cumhuriyet Age in Turkey.  For this aim, on internet and libraries some key word search was done in these tittles "˜John Dewey,  Dewey  and  J. Dewey'. The articles that were suitable were analysed with content analysis technique. After this practice, the articles were collected under some categories and evaluated. At the end of the research in the articles about John Dewey and published in the Cumhuriyet age, it has been found there are many reports on Dewey's life, his views on education and philosophy and evaluations over his Works that has been translated to Turkish, his reports on Turkish Education System, the reflections of his Works to today's education, his views on democratic education and his contributions to Turkish and world education systems

Primary localized amyloidosis of urinary bladder: Case report

Primary amyloidosis of the bladder is a rare pathologicalcondition which the etiology is unknown. The signsand symptoms suggests bladder tumor. In some patients,lower urinary tract symptoms such as lower abdominalpain, frequent urination, dysuria and complaints of grosspainless hematuria occur. In this study a case of primarylocalized amyloidosis of the bladder in a 66 years oldfemale who had gross painless hematuria as the initialsymptom is described.Key words: Amyloidosis, bladder, hematuria

Strategic Excellence in Post-Digital Ecosystems: A B2C Perspective

The basic production of the digital economy is knowledge. As it becomes more important, traditional factors like labor and capital become less so. As technological innovation changes the nature of employment, the conversion of labor to consumption becomes increasingly difficult. E-commerce is the most important driving force of the digital economy. Using technology and information networks effectively allows brands or companies to effect rapid changes in competitive markets. The emergence of neo-consumers calls for a higher order of information exchange and interaction. Companies must reasses their complete business processes in a holistic way to ensure market prominence in an economy driven by social networks and communication. This book deals with the new concepts determining the future path of the digital economy and aims at providing a new perspective to the field.https://digitalcommons.unl.edu/zeabook/1062/thumbnail.jp

Nesfatin-1 levels predict angiographic no-reflow in patients with st-segment elevation myocardial infarction

Background: Nesfatin-1 is a novel peptide possessing pleiotropic metabolic effects. No-reflow phenomenon (NR) is a poor prognostic indicator occurring in around 30% of all patients undergoing primary percutaneous coronary interventions (pPCI). Inflammation and complexity of coronary artery disease (CAD) play pivotal roles in the pathogenesis of NR. In this study, we investigated the relationship between admission serum nesfatin-1 level, NR and complexity of CAD assessed by SYNTAX-1 (SS-1) and SYNTAX-2 (SS-2) scores in patients with ST-segment elevation myocardial infarction (STEMI) undergoing pPCI. Methods: A total of 174 STEMI patients who underwent pPCI were included in the study and divided into NR (n = 36) and normal flow (n = 138) groups. Serum nesfatin-1 was measured by enzyme-linked immunosorbent assay. Seventy-eight consecutive age-, gender-and co-morbidity-matched patients undergoing coronary angiography with < 50% stenosis comprised the control group. Results: Nesfatin-1 levels were significantly lower in the NR group compared to the normal flow and control groups (10.8 ± 6.6 ng/mL vs. 34.9 ± 24 ng/mL vs. 43.6 ± 23.2 ng/mL, respectively, p < 0.001). Nesfatin-1 was significantly and inversely correlated with SS-1 and SS-2 scores (r =-0.709 and r =-0.655, respectively, both p < 0.001). Multivariate logistic regression analysis showed that nesfatin-1 [odds ratio (OR) = 0.81, 95% confidence interval (CI) = 0.708-0.936, p = 0.004] and glomerular filtration rate (OR = 0.94, 95% CI = 0.892-0.989, p = 0.018) were independently associated with NR. In the receiver operating characteristic analysis, nesfatin-1 < 15.21 ng/mL predicted NR with 78.4% sensitivity and 72.2% specificity (area under the curve = 0.809, 95% CI = 0.701-0.918, p < 0.001). Conclusions: Admission nesfatin-1 level is a potent predictor of NR in STEMI patients undergoing pPCI. Additionally, nesfatin-1 has a robust and negative correlation with the complexity of CAD. © 2020, Republic of China Society of Cardiology. All rights reserved

How Does Customer Experience Shape the Attitude Towards and Intention to Brand Switching?

Customer Experience (CeX) and Brand Switching Behavior (BsB) of customers play an important role in the market performance of brands. The underlying relationship between these two constructs to shed light into the success factors in the contemporary consumer markets. This study aimed to (1) explore the relationship between CeX and BsB behavior including Attitude Toward Switch (AtS) and Intention to Switch (ItS), (2) understand the effects of CeX on Customer Satisfaction (CuS), Brand Trust (BaT) and Brand Loyalty (BL), and (3) propose and test a sequential model of these relationships. The results of the study confirmed that positive CeX which has a statistically significant effect on CuS, BaT and BL, eventually leads to the decreasing levels of AtS and ItS through the effect of BL. On the other hand, CuS and BaT are also found to be effective on BL. Finally, AtS is found to be effective on the ItS

A Rare Etiology of Heart Failure: Traumatic Arteriovenous Fistula Due to Stab Injury 17 Years Ago

Background: Although traumatic fistula is frequently encountered, high-output heart failure due to fistula is a very rare condition. Despite an indefinitive history of trauma, arteriovenous (AV) fistula may develop insidiously, and therefore identification of a shunt is highly important for treatment. Case Report: Here we report a 46-year-old male patient with heart failure due to traumatic femoral arterio- venous fistula developed following a penetrating stab injury 17 years ago. Conclusion: Traumatic AV fistula is a curable cause of heart failure. Also, careful examination of the patient is as significant as radiological imaging methods