6 research outputs found

    Aids for the Analyst

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    THE OPEN-SOURCE TURING CODEC: TOWARDS FAST, FLEXIBLE AND PARALLEL HEVC ENCODING

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    The Turing codec is an open-source software codec compliant with the HEVC standard and specifically designed for speed, flexibility, parallelisation and high coding efficiency. The Turing codec was designed starting from a completely novel backbone to comply with the Main and Main10 profiles of HEVC, and has many desirable features for practical codecs such as very low memory consumption, advanced parallelisation schemes and fast encoding algorithms. This paper presents a technical description of the Turing codec as well as a comparison of its performance with other similar encoders. The codec is capable of cutting the encoding complexity by an average 87% with respect to the HEVC reference implementation for an average coding penalty of 11% higher rates in compression efficiency at the same peak-signal-noise-ratio level

    Enzyme Activity and Flexibility at Very Low Hydration

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    Recent measurements have demonstrated enzyme activity at hydrations as low as 3%. This raises the question of whether hydration-induced enzyme flexibility is important for activity. Here, to address this, picosecond dynamic neutron scattering experiments are performed on pig liver esterase powders at 0%, 3%, 12%, and 50% hydration by weight and at temperatures ranging from 120 to 300 K. At all temperatures and hydrations, significant quasielastic scattering intensity is found in the protein, indicating the presence of anharmonic, diffusive motion. As the hydration increases, a temperature-dependent dynamical transition appears and strengthens involving additional diffusive motion. The implication of these results is that, although the additional hydration-induced diffusive motion in the protein detected here may be related to increased activity, it is not required for the enzyme to function
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