31 research outputs found
The Impact of Human Resource Management on Organizational Success: Suggestions for Hospitality Educators
A recent article in the Hospitality and Tourism Educator (Van Hoof, 1991) reported that recruiters for lodging and foodservice organizations consider human resource management (HRM) to be of primary importance when educating hospitality graduate students. The criticality and impact of HRM in the lodging and foodservice industries has been confirmed time and again by recruiters and leaders in the field. And yet, while HRM professionals and corporate leaders publicly acknowledge the importance of HRM, how do operational managers and employees view HRM\u27s role in addressing critical success factors such as increased profitability and enhanced service delivery? Is HRM narrowly confined to the traditional activities of hiring and firing, or is it perceived as having an impact on important strategic issues?
This article reports on a study that examined whether HRM is viewed as having an impact on success factors outside of those traditionally associated with it. Data garnered from a restaurant chain is summarized; however the primary purpose is not to discuss the details of the research, but to consider the implications of the study’s findings for hospitality educators. Thus, the primary objective of this paper is to offer suggestions to educators about how to expose future managers to the potential roles HRM can play in operational issues. Before examining what educators can do to enhance student awareness of how to utilize the principles of HRM, we report on what practicing managers believe is the impact of HRM on critical success factors. Curiously, few researchers have explored systematically the question of whether HRM is perceived to have an impact on critical success factors outside the traditional personnel management domains of selection, retention, and payroll administration
Making Non-Career Jobs Attractive to Younger Workers
As most hospitality industry managers in the U.S. are already aware, there is a growing and persistent shortage of labor available for service-sector, non-career jobs, the very jobs so vital to the industry. In most cases, recruitment efforts for these jobs are targeted toward younger workers, those under age 25. The authors explore issues regarding the attractiveness of non-career jobs in the eyes of young persons and suggest that, in addition to factors related to the job itself (pay, hours, type of work), the type of procedures used by employers to make selection decisions are equally influential. Recommendations are made concerning how hospitality employers with non-career positions to fill can maximize the chances of successfully staffing their organizations
Human Resources as a Strategic Partner in Multiunit-Restaurants
Despite the importance of human-resources issues to the success of chain-restaurant business, a close look at one such company indicates that human resources managers are not yet party to firms’ strategic decision making
Cruise passengers' perceived value and willingness to recommend Valor percebido e disposição para recomendar por parte dos passageiros de cruzeiros
Abstract This paper evaluates cruise passengers perceived value, satisfaction and willingness to recommend a cruise to someone. Passengers aboard an underway ship cruising the Caribbean were surveyed. Regression analyses revealed that, not surprisingly, perceived value and service quality aboard the ship are key determinants of willingness to recommend a cruise to someone else. More interestingly, however, the quality of the food aboard the ship and the degree to which cruisers found the destinations to be relaxing were also significant indicators. Implications for future research and practical recommendations to cruise operators are discussed. Keywords: Cruise, perceived value, satisfaction, willingness to recommend. Resumo Este artigo avalia o valor percebido, a satisfação e a vontade de recomendar por parte dos passageiros de cruzeiro. Valor percebido, satisfação e vontade de recomendar um cruzeiro para alguém. Para o efeito foi aplicado um inquérito a passageiros bordo de um navio de cruzeiro nas Caraíbas. Análises de regressão revelaram que, não surpreendentemente, valor e serviço de qualidade percebida a bordo do navio são os principais determinantes da disposição de recomendar um cruzeiro a outra pessoa. Mais interessante, no entanto, a qualidade da comida a bordo e a medida em que os inquiridos consideraram os destinos relaxantes também foram indicadores significativos. Implicações para futuras pesquisas e recomendações práticas para os operadores de cruzeiros são discutidas. Palavras-chave: Cruzeiros, valor percebido, satisfação, disposição de recomendar
Nutritional supplements, COX-2 and IGF-1 expression in men on active surveillance for prostate cancer
Psychopolitics: Peter Sedgwick’s legacy for mental health movements
This paper re-considers the relevance of Peter Sedgwick's Psychopolitics (1982) for a politics of mental health. Psychopolitics offered an indictment of ‘anti-psychiatry’ the failure of which, Sedgwick argued, lay in its deconstruction of the category of ‘mental illness’, a gesture that resulted in a politics of nihilism. ‘The radical who is only a radical nihilist’, Sedgwick observed, ‘is for all practical purposes the most adamant of conservatives’. Sedgwick argued, rather, that the concept of ‘mental illness’ could be a truly critical concept if it was deployed ‘to make demands upon the health service facilities of the society in which we live’. The paper contextualizes Psychopolitics within the ‘crisis tendencies’ of its time, surveying the shifting welfare landscape of the subsequent 25 years alongside Sedgwick's continuing relevance. It considers the dilemma that the discourse of ‘mental illness’ – Sedgwick's critical concept – has fallen out of favour with radical mental health movements yet remains paradigmatic within psychiatry itself. Finally, the paper endorses a contemporary perspective that, while necessarily updating Psychopolitics, remains nonetheless ‘Sedgwickian’
Gene Expression and Biological Pathways in Tissue of Men with Prostate Cancer in a Randomized Clinical Trial of Lycopene and Fish Oil Supplementation
Studies suggest that micronutrients may modify the risk or delay progression of prostate cancer; however, the molecular mechanisms involved are poorly understood. We examined the effects of lycopene and fish oil on prostate gene expression in a double-blind placebo-controlled randomized clinical trial.Eighty-four men with low risk prostate cancer were stratified based on self-reported dietary consumption of fish and tomatoes and then randomly assigned to a 3-month intervention of lycopene (n = 29) or fish oil (n = 27) supplementation or placebo (n = 28). Gene expression in morphologically normal prostate tissue was studied at baseline and at 3 months via cDNA microarray analysis. Differential gene expression and pathway analyses were performed to identify genes and pathways modulated by these micronutrients.Global gene expression analysis revealed no significant individual genes that were associated with high intake of fish or tomato at baseline or after 3 months of supplementation with lycopene or fish oil. However, exploratory pathway analyses of rank-ordered genes (based on p-values not corrected for multiple comparisons) revealed the modulation of androgen and estrogen metabolism in men who routinely consumed more fish (p = 0.029) and tomato (p = 0.008) compared to men who ate less. In addition, modulation of arachidonic acid metabolism (p = 0.01) was observed after 3 months of fish oil supplementation compared with the placebo group; and modulation of nuclear factor (erythroid derived-2) factor 2 or Nrf2-mediated oxidative stress response for either supplement versus placebo (fish oil: p = 0.01, lycopene: p = 0.001).We did not detect significant individual genes associated with dietary intake and supplementation of lycopene and fish oil. However, exploratory analyses revealed candidate in vivo pathways that may be modulated by these micronutrients.ClinicalTrials.gov NCT00402285
A point-of-care lateral flow assay for neutralising antibodies against SARS-CoV-2
Background: As vaccines against SARS-CoV-2 are now being rolled out, a better understanding of immunity to the virus, whether from infection, or passive or active immunisation, and the durability of this protection is required. This will benefit from the ability to measure antibody-based protection to SARS-CoV-2, ideally with rapid turnaround and without the need for laboratory-based testing.
Methods: We have developed a lateral flow POC test that can measure levels of RBD-ACE2 neutralising antibody (NAb) from whole blood, with a result that can be determined by eye or quantitatively on a small instrument. We compared our lateral flow test with the gold-standard microneutralisation assay, using samples from convalescent and vaccinated donors, as well as immunised macaques.
Findings: We show a high correlation between our lateral flow test with conventional neutralisation and that this test is applicable with animal samples. We also show that this assay is readily adaptable to test for protection to newly emerging SARS-CoV-2 variants, including the beta variant which revealed a marked reduction in NAb activity. Lastly, using a cohort of vaccinated humans, we demonstrate that our whole-blood test correlates closely with microneutralisation assay data (specificity 100% and sensitivity 96% at a microneutralisation cutoff of 1:40) and that fingerprick whole blood samples are sufficient for this test.
Interpretation: Taken together, the COVID-19 NAb-testTM device described here provides a rapid readout of NAb based protection to SARS-CoV-2 at the point of care
IL-10 Blocks the Development of Resistance to Re-Infection with Schistosoma mansoni
Despite effective chemotherapy to treat schistosome infections, re-infection rates are extremely high. Resistance to reinfection can develop, however it typically takes several years following numerous rounds of treatment and re-infection, and often develops in only a small cohort of individuals. Using a well-established and highly permissive mouse model, we investigated whether immunoregulatory mechanisms influence the development of resistance. Following Praziquantel (PZQ) treatment of S. mansoni infected mice we observed a significant and mixed anti-worm response, characterized by Th1, Th2 and Th17 responses. Despite the elevated anti-worm response in PBMC's, liver, spleen and mesenteric lymph nodes, this did not confer any protection from a secondary challenge infection. Because a significant increase in IL-10-producing CD4+CD44+CD25+GITR+ lymphocytes was observed, we hypothesised that IL-10 was obstructing the development of resistance. Blockade of IL-10 combined with PZQ treatment afforded a greater than 50% reduction in parasite establishment during reinfection, compared to PZQ treatment alone, indicating that IL-10 obstructs the development of acquired resistance. Markedly enhanced Th1, Th2 and Th17 responses, worm-specific IgG1, IgG2b and IgE and circulating eosinophils characterized the protection. This study demonstrates that blocking IL-10 signalling during PZQ treatment can facilitate the development of protective immunity and provide a highly effective strategy to protect against reinfection with S. mansoni
Density-Dependent Mortality of the Human Host in Onchocerciasis: Relationships between Microfilarial Load and Excess Mortality
Human onchocerciasis (River Blindness) is a parasitic disease leading to visual impairment including blindness. Blindness may lead to premature death, but infection with the parasite itself (Onchocerca volvulus) may also cause excess mortality in sighted individuals. The excess risk of mortality may not be directly (linearly) proportional to the intensity of infection (a measure of how many parasites an individual harbours). We analyze cohort data from the Onchocerciasis Control Programme in West Africa, collected between 1974 and 2001, by fitting a suite of quantitative models (including a ‘null’ model of no relationship between infection intensity and mortality, a (log-) linear function, and two plateauing curves), and choosing the one that is the most statistically adequate. The risk of human mortality initially increases with parasite density but saturates at high densities (following an S-shape curve), and such risk is greater in younger individuals for a given infection intensity. Our results have important repercussions for programmes aiming to control onchocerciasis (in terms of how the benefits of the programme are calculated), for measuring the burden of disease and mortality caused by the infection, and for a better understanding of the processes that govern the density of parasite populations among human hosts