65 research outputs found

    Study on Dual-spark Ignition Rapid Combustion Characteristic of Opposed-piston Two-stroke GDI Engine

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    AbstractThe mixture formation and combustion process of an opposed-piston two-stroke (OPTS) gasoline direct injection (GDI) engine was carried out by numerical simulation. The effects on in-cylinder combustion and engine performance in different ignition ways of dual-spark ignition have been compared and analyzed. The dual-spark ignition system were installed on cylinder liner could make the in-cylinder combustion more stable and faster. It was benefit for increasing the thermal efficiency and avoiding the knock. Compared with single-spark ignition, dual-spark ignition could shorten flame propagation distance and accelerate flame propagation. Compared with single-spark ignition and synchronous dual-spark ignition models, the rapid combustion period of asynchronous ignition model was shorter, which was helpful to fast burning. In 6000r/min and 15kW full load case, the best ignition angle step of asynchronous ignition was about 10Β° crank angle (CA). When the initial ignition angle was the same, the ignition angle step of asynchronous ignition was smaller and the antiknock was worse

    The role of circadian clock in astrocytes: From cellular functions to ischemic stroke therapeutic targets

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    Accumulating evidence suggests that astrocytes, the abundant cell type in the central nervous system (CNS), play a critical role in maintaining the immune response after cerebral infarction, regulating the blood-brain barrier (BBB), providing nutrients to the neurons, and reuptake of glutamate. The circadian clock is an endogenous timing system that controls and optimizes biological processes. The central circadian clock and the peripheral clock are consistent, controlled by various circadian components, and participate in the pathophysiological process of astrocytes. Existing evidence shows that circadian rhythm controls the regulation of inflammatory responses by astrocytes in ischemic stroke (IS), regulates the repair of the BBB, and plays an essential role in a series of pathological processes such as neurotoxicity and neuroprotection. In this review, we highlight the importance of astrocytes in IS and discuss the potential role of the circadian clock in influencing astrocyte pathophysiology. A comprehensive understanding of the ability of the circadian clock to regulate astrocytes after stroke will improve our ability to predict the targets and biological functions of the circadian clock and gain insight into the basis of its intervention mechanism

    Biomass allocation and yield formation of cotton under partial rootzone irrigation in arid zone

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    Partial rootzone irrigation (PRI) means only part of the root system is exposed to watering at one round of irrigation while the rest part is left in drying soil. The method has been proved a water-saving irrigation without much reduction in yield. This study investigated how the biomass distribution and reproductive development of cotton are affected under PRI. A three-year field irrigation experiment was conducted with a 30% reduction in irrigation amount on cotton in an arid area of Xinjiang in northwest China. Three treatments included conventional furrow irrigation (CFI) as control, alternative furrow irrigation (AFI) and fix furrow irrigation (FFI). PRI decreased stomatal conductance on the days just after irrigation when cotton plants were not under water stress, but there was no difference in stomatal conductance among irrigation treatments when plants were under water stress on the days just before next irrigation. Non-hydraulic signals from the dried rootzone inhibited the stomatal opening under well watered condition, but the moderate water deficit developed in the shoots under PRI may have played a more important role in biomass allocation and yield formation. This moderate water stress reduced shoot biomass accumulation and increased root biomass. While the vegetative and reproductive parts of the shoot were reduced in the same proportion under the PRI, the final yield was much less reduced in PRI, indicating an increased reproductive efficiency of cotton. Furthermore, PRI advanced the development of the reproductive organs and led to earlier flowering. The early matured bolls produced seed-cotton yield with a higher market value. AFI plants consistently performed better than FFI in the 3 years. We conclude that AFI can be used as a better deficit irrigation method with positive regulative effects on stomatal opening and yield forming process

    RAGE Mediates Accelerated Diabetic Vein Graft Atherosclerosis Induced by Combined Mechanical Stress and AGEs via Synergistic ERK Activation

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    Aims/Hypothesis: Diabetes with hypertension rapidly accelerates vascular disease, but the underlying mechanism remains unclear. We evaluated the hypothesis that the receptor of advanced glycation end products (RAGE) might mediate combined signals initiated by diabetes-related AGEs and hypertension-induced mechanical stress as a common molecular sensor. Methods: In vivo surgical vein grafts created by grafting vena cava segments from C57BL/6J mice into the common carotid arteries of streptozotocin (STZ)-treated and untreated isogenic mice for 4 and 8 weeks were analyzed using morphometric and immunohistochemical techniques. In vitro quiescent mouse vascular smooth muscle cells (VSMCs) with either knockdown or overexpression of RAGE were subjected to cyclic stretching with or without AGEs. Extracellular signalregulated kinase (ERK) phosphorylation and Ki-67 expression were investigated. Results: Significant increases in neointimal formation, AGE deposition, Ki-67 expression, and RAGE were observed in the vein grafts of STZ-induced diabetic mice. The highest levels of ERK phosphorylation and Ki-67 expression in VSMCs were induced by simultaneous stretch stress and AGE exposure. The synergistic activation of ERKs and Ki-67 in VSMCs was significantly inhibited by siRNA-RAGE treatment and enhanced by over-expression of RAGE. Conclusion: RAGE may mediate synergistically increased ERK activation and VSMC proliferation induced by mechanica

    Two-Threshold-Variable Integer-Valued Autoregressive Model

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    In the past, most threshold models considered a single threshold variable. However, for some practical applications, models with two threshold variables may be needed. In this paper, we propose a two-threshold-variable integer-valued autoregressive model based on the binomial thinning operator and discuss some of its basic properties, including the mean, variance, strict stationarity, and ergodicity. We consider the conditional least squares (CLS) estimation and discuss the asymptotic normality of the CLS estimator under the known and unknown threshold values. The performances of the CLS estimator are compared via simulation studies. In addition, two real data sets are considered to underline the superior performance of the proposed model

    Simulation Modeling and Optimization of Uniflow Scavenging System Parameters on Opposed-Piston Two-Stroke Engines

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    Based on the introduction of opposed-piston two-stroke (OP2S) gasoline direct injection (GDI) engines, the OP2S-GDI engine working principle and scavenging process were analyzed. GT-Power software was employed to model the working process based on the structural style and principle of OP2S-GDI engine. The tracer gas method and OP2S-GDI engine experiment were employed for model validation at full load of 6000 rpm. The OP2S-GDI engine scavenging system parameters were optimized, including intake port height stroke ratio, intake port circumference ratio, exhaust port height stroke ratio, exhaust port circumference ratio, and opposed-piston motion phase difference. At the same time, the effect of the port height stroke ratio and opposed-piston motion phase difference on effective compression ratio and expansion ratio were considered, and the indicated work was employed as the optimization objective. A three-level orthogonal experiment was applied in the calculation process to reduce the calculation work. The influence and correlation coefficient on the scavenging efficiency and delivery ratio were investigated by the orthogonal experiment analysis of intake and exhaust port height stroke ratio and circular utilization. The effect of the scavenging system parameters on delivery ratio, scavenging efficiency and indicated work were calculated to obtain the best parameters. The results show that intake port height stroke ratio is the main factor for the delivery ratio, while exhaust port height stroke ratio is the main factor to engine delivery ratio and scavenging efficiency

    Unsupervised Anomaly Detection for Intermittent Sequences Based on Multi-Granularity Abnormal Pattern Mining

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    In the actual maintenance of manufacturing enterprises, abnormal changes in after-sale parts demand data often make the inventory strategies unreasonable. Due to the intermittent and small-scale characteristics of demand sequences, it is difficult to accurately identify the anomalies in such sequences using current anomaly detection algorithms. To solve this problem, this paper proposes an unsupervised anomaly detection method for intermittent time series. First, a new abnormal fluctuation similarity matrix is built by calculating the squared coefficient of variation and the maximum information coefficient from the macroscopic granularity. The abnormal fluctuation sequence can then be adaptively screened by using agglomerative hierarchical clustering. Second, the demand change feature and interval feature of the abnormal sequence are constructed and fed into the support vector data description model to perform hypersphere training. Then, the unsupervised abnormal point location detection is realized at the micro-granularity level from the abnormal sequence. Comparative experiments are carried out on the actual demand data of after-sale parts of two large manufacturing enterprises. The results show that, compared with the current representative anomaly detection methods, the proposed approach can effectively identify the abnormal fluctuation position in the intermittent sequence of small samples, and also obtain better detection results

    Research on the Operating Characteristics of Hydraulic Free-Piston Engines: A Systematic Review and Meta-Analysis

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    The hydraulic free-piston engine (HFPE) is a kind of hybrid-powered machine which combines the reciprocating piston-type internal combustion engine and the plunger pump as a whole. In recent years, the HFPE has been investigated by a number of research groups worldwide due to its potential advantages of high efficiency, energy savings, reduced emissions and multi-fuel operation. Therefore, our study aimed to assess the operating characteristics, core questions and research progress of HFPEs via a systematic review and meta-analysis. We included operational control, starting characteristics, misfire characteristics, in-cylinder working processes and operating stability. We conducted the literature search using electronic databases. The research on HFPEs has mainly concentrated on four kinds of free-piston engine, according to piston arrangement form: single piston, dual pistons, opposed pistons and four-cylinder complex configuration. HFPE research in China is mainly conducted in Zhejiang University, Tianjin University, Jilin University and the Beijing Institute of Technology. In addition, in China, research has mainly focused on the in-cylinder combustion process while a piston is free by considering in-cylinder combustion machinery and piston dynamics. Regarding future research, it is very important that we solve the instabilities brought about by chance fluctuations in the combustion process, which will involve the hydraulic system’s efficiency, the cyclical variation, the method of predicting instability and the recovery after instability
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