203 research outputs found

    ESR observations of paramagnetic centers in intrinsic hydrogenated microcrystalline silicon

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    Paramagnetic centers in hydrogenated microcrystalline silicon, µc-Si:H have been studied using dark and light-induced electron-spin resonance (ESR). In dark ESR measurements only one center is observed. The g values obtained empirically from powder-pattern line-shape simulations are g=2.0096 and g'=2.0031. We suggest that this center may be due to defects in the crystalline phase. During illumination at low temperatures, an additional ESR signal appears. This signal is best described by two powder patterns indicating the presence of two centers. One center is asymmetric (gi=1.999, g'=1.996), while the other is characterized by large, unresolved broadening such that unique g values cannot be obtained. The average g value for this center is 1.998. The light-induced signal, which we interpret as coming from carriers trapped in the band tails at the crystalline grain boundaries, remains for at least several minutes after the light is turned off. Although the time scales of the decay curves are very different for two samples prepared by different techniques, both decays can be fitted using the assumption of recombination due to distant pairs of electrons and holes trapped in localized band-tail states

    Persistent and polarised global actin flow is essential for directionality during cell migration

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    Cell migration is hypothesized to involve a cycle of behaviours beginning with leading edge extension. However, recent evidence suggests that the leading edge may be dispensable for migration, raising the question of what actually controls cell directionality. Here, we exploit the embryonic migration of Drosophila macrophages to bridge the different temporal scales of the behaviours controlling motility. This approach reveals that edge fluctuations during random motility are not persistent and are weakly correlated with motion. In contrast, flow of the actin network behind the leading edge is highly persistent. Quantification of actin flow structure during migration reveals a stable organization and asymmetry in the cell-wide flowfield that strongly correlates with cell directionality. This organization is regulated by a gradient of actin network compression and destruction, which is controlled by myosin contraction and cofilin-mediated disassembly. It is this stable actin-flow polarity, which integrates rapid fluctuations of the leading edge, that controls inherent cellular persistence

    Grid Cells, Place Cells, and Geodesic Generalization for Spatial Reinforcement Learning

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    Reinforcement learning (RL) provides an influential characterization of the brain's mechanisms for learning to make advantageous choices. An important problem, though, is how complex tasks can be represented in a way that enables efficient learning. We consider this problem through the lens of spatial navigation, examining how two of the brain's location representations—hippocampal place cells and entorhinal grid cells—are adapted to serve as basis functions for approximating value over space for RL. Although much previous work has focused on these systems' roles in combining upstream sensory cues to track location, revisiting these representations with a focus on how they support this downstream decision function offers complementary insights into their characteristics. Rather than localization, the key problem in learning is generalization between past and present situations, which may not match perfectly. Accordingly, although neural populations collectively offer a precise representation of position, our simulations of navigational tasks verify the suggestion that RL gains efficiency from the more diffuse tuning of individual neurons, which allows learning about rewards to generalize over longer distances given fewer training experiences. However, work on generalization in RL suggests the underlying representation should respect the environment's layout. In particular, although it is often assumed that neurons track location in Euclidean coordinates (that a place cell's activity declines “as the crow flies” away from its peak), the relevant metric for value is geodesic: the distance along a path, around any obstacles. We formalize this intuition and present simulations showing how Euclidean, but not geodesic, representations can interfere with RL by generalizing inappropriately across barriers. Our proposal that place and grid responses should be modulated by geodesic distances suggests novel predictions about how obstacles should affect spatial firing fields, which provides a new viewpoint on data concerning both spatial codes

    За кадры. 1982. № 55 (2430)

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    Связывая с практикой коммунистического строительства. Кафедре истории КПСС-25 лет / А. ГагаринНовая разработка / А. КузнецоваПри участии политехников / А. ОзурПрофсоюзная конференция / А. ЕфимовВыставка литературы / Л. ВласоваИду к цели / В. ПетровКогда собрание не подготовлено / Р. ГорскаяИтоги аттестации / Л. КоробейниковаАктивизировать работу в группах / Л. АлександроваБудет ли порядок в нашем доме? / В. Панкин, И. ЧугуринПадение / Г. ВенделеваМесячник оперативных отрядов / Е. ЗапрягаеваНовое пополнение / Я. ГрунденталерА вы отметились у паспортиста? / Л. ПоздняковаПервое собрание / Д. ШамисПриглашает "Радио - ТПИ" / Л. ЛобачЗвучала музыка стиха / Е. БрестовицкаяЗаслон гриппу / Э. НехорошеваЧто может библиография? / Н. КубраковаЗима спросит строго / В. Бурко
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