2,666 research outputs found

    Reasoning cartographic knowledge in deep learning-based map generalization with explainable AI

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    Cartographic map generalization involves complex rules, and a full automation has still not been achieved, despite many efforts over the past few decades. Pioneering studies show that some map generalization tasks can be partially automated by deep neural networks (DNNs). However, DNNs are still used as black-box models in previous studies. We argue that integrating explainable AI (XAI) into a DL-based map generalization process can give more insights to develop and refine the DNNs by understanding what cartographic knowledge exactly is learned. Following an XAI framework for an empirical case study, visual analytics and quantitative experiments were applied to explain the importance of input features regarding the prediction of a pre-trained ResU-Net model. This experimental case study finds that the XAI-based visualization results can easily be interpreted by human experts. With the proposed XAI workflow, we further find that the DNN pays more attention to the building boundaries than the interior parts of the buildings. We thus suggest that boundary intersection over union is a better evaluation metric than commonly used intersection over union in qualifying raster-based map generalization results. Overall, this study shows the necessity and feasibility of integrating XAI as part of future DL-based map generalization development frameworks

    Inversion formula of multifractal energy dissipation in 3D fully developed turbulence

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    The concept of inverse statistics in turbulence has attracted much attention in the recent years. It is argued that the scaling exponents of the direct structure functions and the inverse structure functions satisfy an inversion formula. This proposition has already been verified by numerical data using the shell model. However, no direct evidence was reported for experimental three dimensional turbulence. We propose to test the inversion formula using experimental data of three dimensional fully developed turbulence by considering the energy dissipation rates in stead of the usual efforts on the structure functions. The moments of the exit distances are shown to exhibit nice multifractality. The inversion formula between the direct and inverse exponents is then verified.Comment: 3 RevTex pages including 3 eps figure

    Iron(II)-Catalyzed Intermolecular Amino-Oxygenation of Olefins through the N−O Bond Cleavage of Functionalized Hydroxylamines

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    An iron-catalyzed diastereoselective intermolecular olefin amino-oxygenation reaction is reported, which proceeds via an iron-nitrenoid generated by the N− O bond cleavage of a functionalized hydroxylamine. In this reaction, a bench-stable hydroxylamine derivative is used as the amination reagent and oxidant. This method tolerates a range of synthetically valuable substrates that have been all incompatible with existing amino-oxygenation methods. It can also provide amino alcohol derivatives with regio- and stereochemical arrays complementary to known amino-oxygenation methods

    Glutamate Excitotoxicity Inflicts Paranodal Myelin Splitting and Retraction.

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    Paranodal myelin damage is observed in white matter injury. However the culprit for such damage remains unknown. By coherent anti-Stokes Raman scattering imaging of myelin sheath in fresh tissues with sub-micron resolution, we observed significant paranodal myelin splitting and retraction following glutamate application both ex vivo and in vivo. Multimodal multiphoton imaging further showed that glutamate application broke axo-glial junctions and exposed juxtaparanodal K+ channels, resulting in axonal conduction deficit that was demonstrated by compound action potential measurements. The use of 4-aminopyridine, a broad-spectrum K+ channel blocker, effectively recovered both the amplitude and width of compound action potentials. Using CARS imaging as a quantitative readout of nodal length to diameter ratio, the same kind of paranodal myelin retraction was observed with applications of Ca2+ ionophore A23187. Moreover, exclusion of Ca2+ from the medium or application of calpain inhibitor abolished paranodal myelin retraction during glutamate exposure. Examinations of glutamate receptor agonists and antagonists further showed that the paranodal myelin damage was mediated by NMDA and kainate receptors. These results suggest that an increased level of glutamate in diseased white matter could impair paranodal myelin through receptor-mediated Ca2+ overloading and subsequent calpain activation

    Modeling the clustering in citation networks

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    For the study of citation networks, a challenging problem is modeling the high clustering. Existing studies indicate that the promising way to model the high clustering is a copying strategy, i.e., a paper copies the references of its neighbour as its own references. However, the line of models highly underestimates the number of abundant triangles observed in real citation networks and thus cannot well model the high clustering. In this paper, we point out that the failure of existing models lies in that they do not capture the connecting patterns among existing papers. By leveraging the knowledge indicated by such connecting patterns, we further propose a new model for the high clustering in citation networks. Experiments on two real world citation networks, respectively from a special research area and a multidisciplinary research area, demonstrate that our model can reproduce not only the power-law degree distribution as traditional models but also the number of triangles, the high clustering coefficient and the size distribution of co-citation clusters as observed in these real networks

    Smaller Genetic Risk in Catabolic Process Explains Lower Energy Expenditure, More Athletic Capability and Higher Prevalence of Obesity in Africans

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    Lower energy expenditure (EE) for physical activity was observed in Africans than in Europeans, which might contribute to the higher prevalence of obesity and more athletic capability in Africans. But it is still unclear why EE is lower among African populations. In this study we tried to explore the genetic mechanism underlying lower EE in Africans. We screened 231 common variants with possibly harmful impact on 182 genes in the catabolic process. The genetic risk, including the total number of mutations and the sum of harmful probabilities, was calculated and analyzed for the screened variants at a population level. Results of the genetic risk among human groups showed that most Africans (3 out of 4 groups) had a significantly smaller genetic risk in the catabolic process than Europeans and Asians, which might result in higher efficiency of generating energy among Africans. In sport competitions, athletes need massive amounts of energy expenditure in a short period of time, so higher efficiency of energy generation might help make African-descendent athletes more powerful. On the other hand, higher efficiency of generating energy might also result in consuming smaller volumes of body mass. As a result, Africans might be more vulnerable to obesity compared to the other races when under the same or similar conditions. Therefore, the smaller genetic risk in the catabolic process might be at the core of understanding lower EE, more athletic capability and higher prevalence of obesity in Africans

    Distant Relative Genetic Algorithm–Based Structural Reliability Optimization

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    In this study, safety margin explicit equation has been established using random variables (i.e., the engineering conditions, structure parameters, structural strength, and external load), and the genetic algorithm (GA)–based structural reliability optimization design has been addressed subsequently. Though the conventional adaptive GA can change automatically with fitness, it is still not unsatisfactory in sufficiently improving the algorithm convergence speed, especially for complex structures. This article presents an improved adaptive technology termed as the distant relative genetic algorithm (DRGA), in which the distant relative pointer and immunity operators can effectively improve the search performance of the GA. In early evolution, by means of cross controlling and avoiding pairing between individuals with the same genes, the methodology prevents the isogenic individuals expanding locally. Besides, the revised algorithm is able to jump out of the local optimal solution, thus ensuring the realization of a fast global convergence. An example based on wing box structure optimization has been demonstrated using the improved method, and the calculation results show that this strategy makes the GA more effective in dealing with the constraint optimization issues

    Highly tunable polarized chromatic plasmonic films based on sub-wavelength grating templates

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    A kind of polarized chromatic plasmonic film is proposed based on subwavelength grating structure, which enables “blue transmission” for the transverse electric light and “red transmission” for the transverse magnetic light. Metal–insulator–metal plasmonic waveguiding and metallic nanowire scattering are revealed to be responsible for the chromatic shift. Based upon the unique transmission spectrum characteristics of such films, polarized chromatic plasmonic tags (PCPTs) can be flexibly fabricated by patterning dielectric grating templates with designed figures and depositing appropriate thickness of metal. These PCPTs, simultaneously possessing directly visible unpolarized transmission colors and concealed distinct polarization‐dependent color shift, can be widely used as anti‐counterfeiting tags with higher security than the diffractive types of holograms

    cis-Tetra­aqua­bis­{5-[4-(1H-imidazol-1-yl-κN 3)phen­yl]tetra­zolido}manganese(II) dihydrate

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    In the title compound, [Mn(C10H7N6)2(H2O)4]·2H2O, the complex unit comprises an Mn2+ ion, coordinated by two imidazole N atoms from cis-related monodentate 5-[4-(imidazol-1-yl)phen­yl]tetra­zolide ligands and four water mol­ecules, together with two water mol­ecules of solvation. The Mn2+ ion lies on a twofold rotation axis and has a slightly distorted octa­hedral geometry. The mol­ecules are connected by O—H⋯N and O—H⋯O hydrogen bonds involving both coordinated and solvent water mol­ecules, generating a three-dimensional structure. Two C atoms of the imidazole ring of the ligand are each disordered over two sites with occupancy factors of 0.75 and 0.25
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