49 research outputs found

    MICRO BUBBLE FORMATION AND BUBBLE DISSOLUTION IN DOMESTIC WET CENTRAL HEATING SYSTEMS

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    16 % of the carbon dioxide emissions in the UK are known to originate from wet domestic central heating systems. Contemporary systems make use of very efficient boilers known as condensing boilers that could result in efficiencies in the 90-100% range. However, research and development into the phenomenon of micro bubbles in such systems has been practically non-existent. In fact, such systems normally incorporate a passive deaerator that is installed as a ‘default’ feature with no real knowledge as to the micro bubble characteristics and their effect on such systems. High saturation ratios are known to occur due to the widespread use of untreated tap water in such systems and due to the inevitable leakage of air into the closed loop circulation system during the daily thermal cycling. The high temperatures at the boiler wall result in super saturation conditions which consequently lead to micro bubble nucleation and detachment, leading to bubbly two phase flow. Experiments have been done on a test rig incorporating a typical 19 kW domestic gas fired boiler to determine the expected saturation ratios and bubble production and dissolution rates in such systems

    Computational Simulation: Selected Applications In Medicine, Dentistry, And Surgery

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    This article presents the use of computational modelling software (e.g. ANSYS) for the purposes of simulating, evaluating and developing medical and surgical practice. We provide a summary of computational simulation mo delling that has recently been employed through effective collaborations between the medical, mathematical and engineering research communities. Here, particular attention is being paid to the modelling of medical devices as well as providing an overview o f modelling bone, artificial organs and microvascular blood flows in the machine space of a High Performance Computer (HPC)

    Computational Non-Newtonian Hemodynamics of Small Vessels

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    The significance of non-Newtonian hemodynamics of small blood vessels is addressed via the description and critical discussion of cogent models within Computational Fluid Dynamics (CFD) software, in this case ANSYS-CFX. Several applicable hemodynamical shear-thinning models are presented and the relevance with respect to prediction of Shear Strain Rate (SSR) rigorously examined, in order to critically evaluate salient literature. It is found that the small vessels explored, in line with the aforementioned literature, that non-Newtionian evaluation of the fluid behavior is indeed negligible. The work presented herein is a precursor to investigation of more complex geometries and hemodynamic simulations, which are being actively researched. This is a technical note which attempts to address the significance of Newtonian/non-Newtonian flows in small blood vessels

    Early expansion of CD38+ICOS+ GC Tfh in draining lymph nodes during influenza vaccination immune response

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    T follicular helper (Tfh) cells provide critical help to B cells during the germinal center (GC) reaction to facilitate generation of protective humoral immunity. Accessing the human lymph node (LN) to study the commitment of CD4 T cells to GC Tfh cell differentiation during in vivo vaccine responses is difficult. We used ultrasound guided fine needle biopsy to monitor recall responses in axillary LNs to seasonal influenza vaccination in healthy volunteers. Specific expansion of GC cell subsets occurred exclusively within draining LNs five days postvaccination. Draining LN GC Tfh and precursor-Tfh cells express higher levels of CD38, ICOS, and Ki67, indicating they were significantly more activated, motile, and proliferating, compared to contralateral LN cells. These observations provide insight into the early expansion phase of the human Tfh lineage within LNs during a vaccine induced memory response and highlights early LN immune responses may not be reflected in the periphery

    Murder in Jerba : honour, shame and hospitality among Maltese in Ottoman Tunisia

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    Little is known about the sizeable Maltese communities developing along the southern and eastern shores of the Mediterranean in the mid-nineteenth century and the extent to which the migrants reproduced Maltese cultural traditions and practices overseas. This article considers this question through a microhistorical analysis of events culminating in the murder of a Maltese woman in the Ottoman Regency of Tunis in 1866. A close reading of transcripts from the interrogation of witnesses and the accused, all members of a Maltese community in Jerba reveals their shared cultural practices and beliefs surrounding the provision of hospitality, honour and shame. Viewed from this perspective, the curious responses of the witnesses to the murder of their compatriot become meaningful, and the crime is reframed as an honour killing.peer-reviewe

    CFD analysis of the two-phase bubbly flow characteristics in helically coiled rectangular and circular tube heat exchangers

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    Due to their ease of manufacture, high heat transfer efficiency and compact design, helically coiled heat exchangers are increasingly being adopted in a number of industries. The higher heat transfer efficiency over straight pipes is due to the secondary flow that develops as a result of the centrifugal force. In spite of the widespread use of helically coiled heat exchangers, and the presence of bubbly two-phase flow in a number of systems, very few studies have investigated the resultant flow characteristics. This paper will therefore present the results of CFD simulations for the two-phase bubbly flow in helically coiled heat exchangers as a function of the volumetric void fraction and the tube cross-section design. The CFD results are compared to the scarce flow visualisation experimental results available in the open literature
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