Absorption spectra of Q 0000-263 and Q 1442+101

Studying the Lyman-alpha forest allows us to trace the cosmological distribution of matter through time, and may reveal insights into important questions such as the onset of galaxy formation. An equation for determining the number of Lyman-alpha absorption lines per redshift per rest equivalent in the Lyman-alpha forest is given. For a nonevolving population of clouds gamma = 1 for q(sub 0) = 0, and gamma = 0.5 for q(sub 0) = 0.5. A detailed study of the Lyman-alpha forests of Q 1442+101 at z(sub em) = 3.54 and Q 0000-263 at z(sub em) = 4.11

The Origin of \lya Absorption Systems at z>1z>1---Implications from the Hubble Deep Field

The Hubble Deep Field images have provided us with a unique chance to relate statistical properties of high-redshift galaxies to statistical properties of \lya absorption systems. Combining an {\em empirical} measure of the galaxy surface density versus redshift with an {\em empirical} measure of the gaseous extent of galaxies, we predict the number density of \lya absorption systems that originate in extended gaseous envelopes of galaxies versus redshift. We show that at least 50% and as much as 100% of observed \lya absorption systems of W\apg0.32 \AA can be explained by extended gaseous envelops of galaxies. Therefore, we conclude that known galaxies of known gaseous extent must produce a significant fraction and perhaps all of \lya absorption systems over a large redshift range.Comment: 12 pages, 3 figures, accepted for publication in the Astrophysical Journal, April 10, 2000 issu

Turmeric inhibits parathyroid hormone-related protein (PTHrP) secretion from human rheumatoid synoviocytes

Excessive production of parathyroid hormone-related protein (PTHrP) by tumor-like synoviocytes contributes to joint destruction in rheumatoid arthritis (RA). Having previously demonstrated that curcuminoid-only and essential oil-only fractions of turmeric prevent joint destruction in an animal model of RA, we hypothesized that synoviocyte PTHrP production could be one signaling pathway targeted by turmeric (Curcuma longa L.) in RA

BIMA and Keck Imaging of the Radio Ring PKS 1830-211

We discuss BIMA (Berkeley Illinois Maryland Association) data and present new high quality optical and near-IR Keck images of the bright radio ring PKS 1830-211. Applying a powerful new deconvolution algorithm we have been able to identify both images of the radio source. In addition we recover an extended source in the optical, consistent with the expected location of the lensing galaxy. The source counterparts are very red, I-K=7, suggesting strong Galactic absorption with additional absorption by the lensing galaxy at z=0.885, and consistent with the detection of high redshift molecules in the lens.Comment: To be published in the ASP Conference Proceedings, 'Highly Redshifted Radio Lines', Greenbank, W

CLASH-VLT: Testing the Nature of Gravity with Galaxy Cluster Mass Profiles

We use high-precision kinematic and lensing measurements of the total mass profile of the dynamically relaxed galaxy cluster MACS J1206.2-0847 at $z=0.44$ to estimate the value of the ratio $\eta=\Psi/\Phi$ between the two scalar potentials in the linear perturbed Friedmann-Lemaitre-Robertson-Walker metric.[...] Complementary kinematic and lensing mass profiles were derived from exhaustive analyses using the data from the Cluster Lensing And Supernova survey with Hubble (CLASH) and the spectroscopic follow-up with the Very Large Telescope (CLASH-VLT). Whereas the kinematic mass profile tracks only the time-time part of the perturbed metric (i.e. only $\Phi$), the lensing mass profile reflects the contribution of both time-time and space-space components (i.e. the sum $\Phi+\Psi$). We thus express $\eta$ as a function of the mass profiles and perform our analysis over the radial range $0.5\,Mpc\le r\le r_{200}=1.96\,Mpc$. Using a spherical Navarro-Frenk-White mass profile, which well fits the data, we obtain \eta(r_{200})=1.01\,_{-0.28}^{+0.31} at the 68\% C.L. We discuss the effect of assuming different functional forms for mass profiles and of the orbit anisotropy in the kinematic reconstruction. Interpreting this result within the well-studied $f(R)$ modified gravity model, the constraint on $\eta$ translates into an upper bound to the interaction length (inverse of the scalaron mass) smaller than 2 Mpc. This tight constraint on the $f(R)$ interaction range is however substantially relaxed when systematic uncertainties in the analysis are considered. Our analysis highlights the potential of this method to detect deviations from general relativity, while calling for the need of further high-quality data on the total mass distribution of clusters and improved control on systematic effects.Comment: 18 pages, 3 figures, submitted to JCA

LensPerfect: Gravitational Lens Massmap Reconstructions Yielding Exact Reproduction of All Multiple Images

We present a new approach to gravitational lens massmap reconstruction. Our massmap solutions perfectly reproduce the positions, fluxes, and shears of all multiple images. And each massmap accurately recovers the underlying mass distribution to a resolution limited by the number of multiple images detected. We demonstrate our technique given a mock galaxy cluster similar to Abell 1689 which gravitationally lenses 19 mock background galaxies to produce 93 multiple images. We also explore cases in which far fewer multiple images are observed, such as four multiple images of a single galaxy. Massmap solutions are never unique, and our method makes it possible to explore an extremely flexible range of physical (and unphysical) solutions, all of which perfectly reproduce the data given. Each reconfiguration of the source galaxies produces a new massmap solution. An optimization routine is provided to find those source positions (and redshifts, within uncertainties) which produce the "most physical" massmap solution, according to a new figure of merit developed here. Our method imposes no assumptions about the slope of the radial profile nor mass following light. But unlike "non-parametric" grid-based methods, the number of free parameters we solve for is only as many as the number of observable constraints (or slightly greater if fluxes are constrained). For each set of source positions and redshifts, massmap solutions are obtained "instantly" via direct matrix inversion by smoothly interpolating the deflection field using a recently developed mathematical technique. Our LensPerfect software is straightforward and easy to use and is made publicly available via our website.Comment: 17 pages, 18 figures, accepted by ApJ. Software and full-color version of paper available at http://www.its.caltech.edu/~coe/LensPerfect

Protection of Trabecular Bone in Ovariectomized Rats by Turmeric (Curcuma longa L.) is Dependent on Extract Composition

This document is the Accepted Manuscript version of a Published Work that appeared in final form in the Journal of Agricultural and Food Chemistry, copyright © American Chemical Society after peer review and technical editing by the publisher. To access the final edited and published work see http://doi.org/10.1021/jf101873fExtracts prepared from turmeric (Curcuma longa L., [Zingiberaceae]) containing bioactive phenolic curcuminoids were evaluated for bone-protective effects in a hypogonadal rat model of postmenopausal osteoporosis. Three-month female Sprague Dawley rats were ovariectomized (OVX) and treated with a chemically complex turmeric fraction (41% curcuminoids by weight) or a curcuminoid-enriched turmeric fraction (94% curcuminoids by weight), both dosed at 60mg/kg 3x per week, or vehicle alone. Effects of two months of treatment on OVX-induced bone loss were followed prospectively by serial assessment of bone mineral density (BMD) of the distal femur using dual-energy x-ray absorptiometry (DXA), while treatment effects on trabecular bone microarchitecture were assessed at two months by micro-computerized tomography (μCT). Chemically complex turmeric did not prevent bone loss, however, the curcuminoid-enriched turmeric prevented up to 50% of OVX-induced loss of trabecular bone and also preserved the number and connectedness of the strut-like trabeculae. These results suggest that turmeric may have bone-protective effects but that extract composition is a critical factor

Spectral Evidence for Widespread Galaxy Outflows at z>4

We present discovery spectra of a sample of eight lensed galaxies at high redshift, 3.7<z<5.2, selected by their red colors in the fields of four massive clusters: A1689, A2219, A2390, and AC114. Metal absorption lines are detected and observed to be blueshifted by 300-800 km/s with respect to the centroid of Ly-alpha emission. A correlation is found between this blueshift and the equivalent width of the metal lines, which we interpret as a broadening of saturated absorption lines caused by a dispersion in the outflow velocity of interstellar gas. Local starburst galaxies show similar behavior, associated with obvious gas outflows. We also find a trend of increasing equivalent width of Ly-alpha emission with redshift, which may be a genuine evolutionary effect towards younger stellar populations at high redshift with less developed stellar continua. No obvious emission is detected below the Lyman limit in any of our spectra, nor in deep U or B-band images. The UV continua are reproduced well by early B-stars, although some dust absorption would allow a fit to hotter stars. After correcting for the lensing, we derive small physical sizes for our objects, ~0.5-5 kpc/h for a flat cosmology with Omega_m=0.3, Omega_Lambda=0.7. The lensed images are only marginally resolved in good seeing despite their close proximity to the critical curve, where large arcs are visible and hence high magnifications of up to ~20x are inferred. Two objects show a clear spatial extension of the Ly-alpha emission relative to the continuum starlight, indicating a ``breakout'' of the gas. The sizes of our galaxies together with their large gas motion suggests that outflows of gas are common at high redshift and associated with galaxy formation.Comment: 48 pages, 16 figures, ApJ, in press. Manuscript with full resolution color images available at (http://astro.princeton.edu/~bfrye