13,540 research outputs found

    Effectiveness of nurse home-visiting for disadvantaged families: results of a natural experiment

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    Extent: 9p.Objective: To evaluate the effects of a postnatal home-visiting programme delivered by community health nurses to socially disadvantaged mothers in South Australia. Design: The intervention group of 428 mothers lived in metropolitan Adelaide and the comparison group of 239 mothers lived in regional towns where the programme was not yet available. All participating mothers met health service eligibility criteria for enrolment in the home-visiting programme. Participants in both groups were assessed at baseline (mean child age=14.4 weeks SD=2.3), prior to programme enrolment, and again when the children were aged 9, 18 and 24 months. Setting: State-wide community child health service. Participants: 667 socially disadvantaged mothers enrolled consecutively. 487 mothers (73%) completed the 24-month assessment. Intervention: Two-year postnatal home-visiting programme based on the Family Partnership Model. Primary outcome measures: Parent Stress Index (PSI), Kessler Psychological Distress Scale and the Ages and Stages Questionnaire. Results: Mixed models adjusting for baseline differences were used to compare outcomes in the two groups. The mothers in the home-visiting group reported greater improvement on the PSI subscales assessing a mother's perceptions on the quality of their relationship with their child (1.10, 95% CI 0.06 to 2.14) and satisfaction with their role as parents (0.46, 95% CI −0.15 to 1.07) than mothers in the comparison group. With the exception of childhood sleeping problems, there were no other significant differences in the outcomes across the two groups. Conclusions: The findings suggest that home-visiting programmes delivered by community health nurses as part of routine clinical practice have the potential to improve maternal–child relationships and help mothers adjust to their role as parents.Michael Gifford Sawyer, Linda Frost, Kerrie Bowering, John Lync

    Intercalation of Hydrotalcites with Hexacyanoferrate(II) and (III)-a ThermoRaman Spectroscopic Study

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    Raman spectroscopy using a hot stage indicates that the intercalation of hexacyanoferrate(II) and (III) in the interlayer space of a Mg,Al hydrotalcites leads to layered solids where the intercalated species is both hexacyanoferrate(II) and (III). Raman spectroscopy shows that depending on the oxidation state of the initial hexacyanoferrate partial oxidation and reduction takes place upon intercalation. For the hexacyanoferrate(III) some partial reduction occurs during synthesis. The symmetry of the hexacyanoferrate decreases from Oh existing for the free anions to D3d in the hexacyanoferrate interlayered hydrotalcite complexes. Hot stage Raman spectroscopy reveals the oxidation of the hexacyanoferrate(II) to hexacyanoferrate(III) in the hydrotalcite interlayer with the removal of the cyanide anions above 250 °C. Thermal treatment causes the loss of CN ions through the observation of a band at 2080 cm-1. The hexacyanoferrate (III) interlayered Mg,Al hydrotalcites decomposes above 150 °C

    Temporal and spectral characteristics of solar flare hard X-ray emission

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    Solar Maximum Mission observations of three flares that impose stringent constraints on physical models of the hard X-ray production during the impulsive phase are presented. Hard X-ray imaging observations of the flares on 1980 November 5 at 22:33 UT show two patches in the 16 to 30 keV images that are separated by 70,000 km and that brighten simultaneously to within 5 s. Observations to O V from one of the footprints show simultaneity of the brightening in this transition zone line and in the total hard X-ray flux to within a second or two. These results suggest but do not require the existence of electron beams in this flare. The rapid fluctuations of the hard X-ray flux within some flares on the time scales of 1 s also provide evidence for electron beams and limits on the time scale of the energy release mechanism. Observations of a flare on 1980 June 6 at 22:34 UT show variations in the 28 keV X-ray counting rate from one 20 ms interval to the next over a period of 10 s. The hard X-ray spectral variations measured with 128 ms time resolution for one 0.5 s spike during this flare are consistent with the predictions of thick-target non-thermal beam model

    Viral dynamics during structured treatment interruptions of chronic human immunodeficiency virus type 1 infection

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    Although antiviral agents which block human immunodeficiency virus (HIV) replication can result in long-term suppression of viral loads to undetectable levels in plasma, long-term therapy fails to eradicate virus, which generally rebounds after a single treatment interruption. Multiple structured treatment interruptions (STIs) have been suggested as a possible strategy that may boost HIV-specific immune responses and control viral replication. We analyze viral dynamics during four consecutive STI cycles in 12 chronically infected patients with a history (>2 years) of viral suppression under highly active antiretroviral therapy. We fitted a simple model of viral rebound to the viral load data from each patient by using a novel statistical approach that allows us to overcome problems of estimating viral dynamics parameters when there are many viral load measurements below the limit of detection. There is an approximate halving of the average viral growth rate between the first and fourth STI cycles, yet the average time between treatment interruption and detection of viral loads in the plasma is approximately the same in the first and fourth interruptions. We hypothesize that reseeding of viral reservoirs during treatment interruptions can account for this discrepancy, although factors such as stochastic effects and the strength of HIV-specific immune responses may also affect the time to viral rebound. We also demonstrate spontaneous drops in viral load in later STIs, which reflect fluctuations in the rates of viral production and/or clearance that may be caused by a complex interaction between virus and target cells and/or immune responses

    The MgSiO_3 system at high pressure: Thermodynamic properties of perovskite, postperovskite, and melt from global inversion of shock and static compression data

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    We present new equation-of-state (EoS) data acquired by shock loading to pressures up to 245 GPa on both low-density samples (MgSiO_3 glass) and high-density, polycrystalline aggregates (MgSiO_3 perovskite + majorite). The latter samples were synthesized using a large-volume press. Modeling indicates that these materials transform to perovskite, postperovskite, and/or melt with increasing pressure on their Hugoniots. We fit our results together with existing P-V-T data from dynamic and static compression experiments to constrain the thermal EoS for the three phases, all of which are of fundamental importance to the dynamics of the lower mantle. The EoS for perovskite and postperovskite are well described with third-order Birch-Murnaghan isentropes, offset with a Mie-Grüneisen-Debye formulation for thermal pressure. The addition of shock data helps to distinguish among discrepant static studies of perovskite, and for postperovskite, constrain a value of K' significantly larger than 4. For the melt, we define for the first time a single EoS that fits experimental data from ambient pressure to 230 GPa; the best fit requires a fourth-order isentrope. We also provide a new EoS for Mg_2SiO_4 liquid, calculated in a similar manner. The Grüneisen parameters of the solid phases decrease with pressure, whereas those of the melts increase, consistent with previous shock wave experiments as well as molecular dynamics simulations. We discuss implications of our modeling for thermal expansion in the lower mantle, stabilization of ultra-low-velocity zones associated with melting at the core-mantle boundary, and crystallization of a terrestrial magma ocean

    Image synthesis for SAR system, calibration and processor design

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    The Point Scattering Method of simulating radar imagery rigorously models all aspects of the imaging radar phenomena. Its computational algorithms operate on a symbolic representation of the terrain test site to calculate such parameters as range, angle of incidence, resolution cell size, etc. Empirical backscatter data and elevation data are utilized to model the terrain. Additionally, the important geometrical/propagation effects such as shadow, foreshortening, layover, and local angle of incidence are rigorously treated. Applications of radar image simulation to a proposed calibrated SAR system are highlighted: soil moisture detection and vegetation discrimination

    The Effect of Particle Strength on the Ballistic Resistance of Shear Thickening Fluids

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    The response of shear thickening fluids (STFs) under ballistic impact has received considerable attention due to its field-responsive nature. While efforts have primarily focused on the response of traditional ballistic fabrics impregnated with fluids, the response of pure STFs to penetration has received limited attention. In the present study, the ballistic response of pure STFs is investigated and the effect of fluid density and particle strength on ballistic performance is isolated. The loss of ballistic resistance of STFs at higher impact velocities is governed by particle strength, indicating the range of velocities over which they may provide effective armor solutions.Comment: 4 pages, 4 figure

    Electromagnetic containerless processing requirements and recommended facility concept and capabilities for space lab

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    Containerless melting, reaction, and solidification experiments and processes which potentially can lead to new understanding of material science and production of new or improved materials in the weightless space environment are reviewed in terms of planning for spacelab. Most of the experiments and processes discussed are amenable to the employment of electromagnetic position control and electromagnetic induction or electron beam heating and melting. The spectrum of relevant properties of materials, which determine requirements for a space laboratory electromagnetic containerless processing facility are reviewed. Appropriate distributions and associated coil structures are analyzed and compared on the basis of efficiency, for providing the functions of position sensing, control, and induction heating. Several coil systems are found capable of providing these functions. Exchangeable modular coils in appropriate sizes are recommended to achieve the maximum power efficiencies, for a wide range of specimen sizes and resistivities, in order to conserve total facility power

    High energy X-ray spectra of cygnus XR-1 observed from OSO-8

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    X-ray spectra of Cygnus XR-1 were measured with the scintillation spectrometer on board the OSO-8 satellite during a period of one and one-half to three weeks in each of the years from 1975 to 1977. Observations were made when the source was both in a high state and in a low state. Typical spectra of the source between 15 and 250 keV are presented. The observed pivoting effect is consistent with two temperature accretion disk models of the X-ray emitting region. No significant break in the spectrum occurred at energies up to 150 keV. The high state as defined in the 3 to 6 keV bandwidth was found to be the higher luminosity state of the X-ray source. One transition from a low to a high state occurred during observations. The time of occurrence of this and other transitions is consistent with the hypothesis that all intensity transitions occur near periastron of the binary system, and that such transitions are caused by changes in the mass transfer rate between the primary and the accretion disk around the secondary
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