Electron-ion recombination of Si IV forming Si III: Storage-ring measurement and multiconfiguration Dirac-Fock calculations

The electron-ion recombination rate coefficient for Si IV forming Si III was measured at the heavy-ion storage-ring TSR. The experimental electron-ion collision energy range of 0-186 eV encompassed the 2p(6) nl n'l' dielectronic recombination (DR) resonances associated with 3s to nl core excitations, 2s 2p(6) 3s nl n'l' resonances associated with 2s to nl (n=3,4) core excitations, and 2p(5) 3s nl n'l' resonances associated with 2p to nl (n=3,...,infinity) core excitations. The experimental DR results are compared with theoretical calculations using the multiconfiguration Dirac-Fock (MCDF) method for DR via the 3s to 3p n'l' and 3s to 3d n'l' (both n'=3,...,6) and 2p(5) 3s 3l n'l' (n'=3,4) capture channels. Finally, the experimental and theoretical plasma DR rate coefficients for Si IV forming Si III are derived and compared with previously available results.Comment: 13 pages, 9 figures, 3 tables. Accepted for publication in Physical Review

Determination of the Her-2/neu gene amplification status in cytologic breast cancer specimens using automated silver-enhanced in-situ hybridization (SISH)

Silver-enhanced in-situ hybridization (SISH) is an emerging tool for the determination of the Her-2/neu amplification status in breast cancer. SISH is technically comparable to fluorescence in-situ hybridization (FISH) but does not require a fluorescence microscope for its interpretation. Although recent studies on histologic evaluations of SISH are promising, we aimed to evaluate its performance on 71 cytologic breast cancer specimens with the new combined Her-2/Chr17 probe. Her-2/neu status as routinely determined by FISH was available for all patients. We found SISH signals in cytologic cell blocks and smear specimens easy to evaluate in most cases. Small numbers of tumor cells and difficulties in identifying tumor cells in lymphocyte-rich backgrounds were limiting factors. Her-2/neu status, as determined by Her-2/Chr17 SISH, was basically identical to the results of the corresponding FISH. The discrepancies were mainly owing to the heterogeneity of Her-2/neu amplification in the tumor tissue. Interobserver agreement for the SISH evaluation was high (kappa value: 0.972). We conclude that Her-2/Chr17 SISH is a useful and accurate method for the evaluation of the Her-2/neu gene amplification status in cytologic breast cancer specimens, particularly in metastatic breast cancer lesions. The advantages of signal permanency and bright-field microscopic result interpretation make this technique an attractive alternative to the current FISH-based gold standard

Bestimmung der Steifigkeitsparameter von zweilagigen Litzen

In der vorliegenden Arbeit werden Ergebnisse zu analytischen, numerischen und experimentellen Steifigkeitsuntersuchungen an zweilagigen Litzen vorgestellt. Berücksichtigt werden dabei die Grundbeanspruchungsarten Zug, Torsion und Biegung. Bei den analytischen und numerischen Verfahren wird linearelastisches Materialverhalten vorausgesetzt. Die analytische Bestimmung des Litzenverhaltens erfolgte auf der Grundlage zweier aus der Literatur bekannter Methoden. Bei der numerischen Berechnung der Steifigkeitsparameter wurde auf der Basis der Methode der Finiten Elemente für die Litzen ein einfaches Stab-Modell entwickelt. Für die Berechnung wurde das Finite-Element-Programm COSAR verwendet. Die experimentellen Untersuchungen erfolgten auf einer Hydropulsanlage. Da für die experimentellen Untersuchungen zweilagige Litzen mit speziellen Querschnittsabmessungen vorlagen, beschränken sich auch die numerischen Modelle auf diese Querschnitte. Eine Anwendung der Berechnungsmethoden und eine Entwicklung von Modellen auf deren Grundlage für ein- und mehrlagige Litzen mit anderen Querschnitten ist möglich

Роми України і Миколаївщини

У статті розглянуто історію появи ромів на території України. Наприкінці ХVIII ст. 9-а ревізія виявила ромськенаселення уХерсонськійгубернії (територія сучасної Миколаївщини). Зараз у цьому регіоні проживає понад 1500 ромів.В статье рассмотрена история появления ромов на территории Украины. В конце ХVIII ст. 9-я ревизия зафиксировала наличие цыганского населения в Херсонской губернии (территория современной Николаевщины). Сейчас в этом регионе проживает более 1500 ромов.History of appearance of Romanies on the territory of Ukraine is considered in the thesis. At the end of 18th century Romanies are fixed in the 9th revision on the territory of Kherson province (modern Mykolaiv region). There are more than 1500 Romanies in this region now

Semiseparable integral operators and explicit solution of an inverse problem for the skew-self-adjoint Dirac-type system

Inverse problem to recover the skew-self-adjoint Dirac-type system from the generalized Weyl matrix function is treated in the paper. Sufficient conditions under which the unique solution of the inverse problem exists, are formulated in terms of the Weyl function and a procedure to solve the inverse problem is given. The case of the generalized Weyl functions of the form $\phi(\lambda)\exp\{-2i\lambda D\}$, where $\phi$ is a strictly proper rational matrix function and $D=D^* \geq 0$ is a diagonal matrix, is treated in greater detail. Explicit formulas for the inversion of the corresponding semiseparable integral operators and recovery of the Dirac-type system are obtained for this case

WASp-dependent actin cytoskeleton stability at the dendritic cell immunological synapse is required for extensive, functional T cell contacts

The immunological synapse is a highly structured and molecularly dynamic interface between communicating immune cells. Although the immunological synapse promotes T cell activation by dendritic cells, the specific organization of the immunological synapse on the dendritic cell side in response to T cell engagement is largely unknown. In this study, confocal and electron microscopy techniques were used to investigate the role of dendritic cell actin regulation in immunological synapse formation, stabilization, and function. In the dendritic cell-restricted absence of the Wiskott-Aldrich syndrome protein, an important regulator of the actin cytoskeleton in hematopoietic cells, the immunological synapse contact with T cells occupied a significantly reduced surface area. At a molecular level, the actin network localized to the immunological synapse exhibited reduced stability, in particular, of the actin-related protein-2/3-dependent, short-filament network. This was associated with decreased polarization of dendritic cell-associated ICAM-1 and MHC class II, which was partially dependent on Wiskott-Aldrich syndrome protein phosphorylation. With the use of supported planar lipid bilayers incorporating anti-ICAM-1 and anti-MHC class II antibodies, the dendritic cell actin cytoskeleton organized into recognizable synaptic structures but interestingly, formed Wiskott-Aldrich syndrome protein-dependent podosomes within this area. These findings demonstrate that intrinsic dendritic cell cytoskeletal remodeling is a key regulatory component of normal immunological synapse formation, likely through consolidation of adhesive interaction and modulation of immunological synapse stability

Coupled tensorial form for atomic relativistic two-particle operator given in second quantization representation

General formulas of the two-electron operator representing either atomic or effective interactions are given in a coupled tensorial form in relativistic approximation. The alternatives of using uncoupled, coupled and antisymmetric two-electron wave functions in constructing coupled tensorial form of the operator are studied. The second quantization technique is used. The considered operator acts in the space of states of open-subshell atoms

Two-loop SUSY QCD corrections to the chargino masses in the MSSM

We have calculated the two-loop strong interaction corrections to the chargino pole masses in the DRbar'-scheme in the Minimal Supersymmetric Standard Model (MSSM) with complex parameters. We have performed a detailed numerical analysis for a particular point in the parameter space and found corrections of a few tenths of a percent. We provide a computer program which calculates chargino and neutralino masses with complex parameters including the one-loop corrections and all two-loop SQCD effects.Comment: 12 pages, 11 figures, references modified, clarifications adde

On the class SI of J-contractive functions intertwining solutions of linear differential equations

In the PhD thesis of the second author under the supervision of the third author was defined the class SI of J-contractive functions, depending on a parameter and arising as transfer functions of overdetermined conservative 2D systems invariant in one direction. In this paper we extend and solve in the class SI, a number of problems originally set for the class SC of functions contractive in the open right-half plane, and unitary on the imaginary line with respect to some preassigned signature matrix J. The problems we consider include the Schur algorithm, the partial realization problem and the Nevanlinna-Pick interpolation problem. The arguments rely on a correspondence between elements in a given subclass of SI and elements in SC. Another important tool in the arguments is a new result pertaining to the classical tangential Schur algorithm.Comment: 46 page