Where are you from, stranger? The enigmatic biogeography of North African pond turtles (Emys orbicularis) .

Abstract The European pond turtle (Emys orbicularis) is a Nearctic element in the African fauna and thought to have invaded North Africa from the Iberian Peninsula. All North African populations are currently identified with the subspecies E. o. occidentalis. However, a nearly range-wide sampling in North Africa used for analyses of mitochondrial and microsatellite DNA provides evidence that only Moroccan populations belong to this taxon, while eastern Algerian and Tunisian pond turtles represent an undescribed distinct subspecies. These two taxa are most closely related to E. o. galloitalica with a native distribution along the Mediterranean coast of northern Spain through southern France to western and southern Italy. This group is sister to a clade comprising several mitochondrial lineages and subspecies of E. orbicularis from Central and Eastern Europe plus Asia, and the successive sisters are E. o. hellenica and E. trinacris. Our results suggest that E. orbicularis has been present in North Africa longer than on the Iberian Peninsula and that after an initial invasion of North Africa by pond turtles from an unknown European source region, there was a phase of diversification in North Africa, followed by a later re-invasion of Europe by one of the African lineages. The differentiation of pond turtles in North Africa parallels a general phylogeographic paradigm in amphibians and reptiles, with deeply divergent lineages in the western and eastern Maghreb. Acknowledging their genetic similarity, we propose to synonymize the previously recognized Iberian subspecies E. o. fritzjuergenobsti with E. o. occidentalis sensu stricto. The seriously imperiled Moroccan populations of E. o. occidentalis represent two Management Units different in mitochondrial haplotypes and microsatellite markers. The conservation status of eastern Algerian pond turtles is unclear, while Tunisian populations are endangered. Considering that Algerian and Tunisian pond turtles represent an endemic taxon, their situation throughout the historical range should be surveyed to establish a basis for conservation measures

Life after shock: the mission from Mars to Earth

Extract from introduction: The minerals of the Martian meteorites collected so far indicate an exposure to shock waves in the pressure range of 5 to 55 GPa [1]. As terrestrial rocks are frequently inhabited by microbial communities, rocks ejected from a planet by impact processes may carry with them endolithic microorganisms, if microbial life existed/exists on this planet

IL-33 signaling regulates innate and adaptive immunity to Cryptococcus neoformans.

Susceptibility to progressive infection with the fungus Cryptococcus neoformans is associated with an allergic pattern of lung inflammation, yet the factors that govern this host response are not clearly understood. Using a clinically relevant mouse model of inhalational infection with virulent C. neoformans H99, we demonstrate a role for IL-33-dependent signaling in host immune defense. Infection of BALB/c mice with 10(4) CFU of C. neoformans H99 caused a time-dependent induction of IL-33 with accumulation of type 2 pulmonary innate lymphoid cells and alternatively activated macrophages in the lungs as well as Th2-polarized CD4(+) T cells in draining lymph nodes. IL-33R subunit T1/ST2-deficient (T1/ST2(-/-)) mice infected with C. neoformans H99 had improved survival with a decreased fungal burden in the lungs, spleen, and brain, compared with wild-type mice. Signaling through T1/ST2 was required for the accumulation and early production of IL-5 and IL-13 by lung type 2 pulmonary innate lymphoid cells. Further analysis of T1/ST2(-/-) mice revealed increased fungicidal exudate macrophages in the lungs and decreased C. neoformans-specific Th2 cells in the mediastinal lymph nodes. T1/ST2 deficiency also diminished goblet cell hyperplasia, mucus hypersecretion, bronchoalveolar lavage eosinophilia, alternative activation of macrophages, and serum IgE. These observations demonstrate that IL-33-dependent signaling contributes to the expansion of innate type 2 immunity and subsequent Th2-biased lung immunopathology that facilitates C. neoformans growth and dissemination

The influence of shock pressure, pre-shock temperature, and host rock composition on the survival rate of endolithic microorganisms during impact ejection from Mars

Petrographic and biological analysis of shock recovery experiments confirms the possible life transport due to an impact from Mars to Earth

CLASH-VLT: Strangulation of cluster galaxies in MACSJ0416.1-2403 as seen from their chemical enrichment

(abridged) We explore the Frontier Fields cluster MACS J0416.1-2403 at z=0.3972 with VIMOS/VLT spectroscopy from the CLASH-VLT survey covering a region which corresponds to almost three virial radii. We measure fluxes of 5 emission lines of 76 cluster members enabling us to unambiguously derive O/H gas metallicities, and also SFRs from Halpha. For intermediate massses we find a similar distribution of cluster and field galaxies in the MZR and mass vs. sSFR diagrams. Bulge-dominated cluster galaxies have on average lower sSFRs and higher O/Hs compared to their disk-dominated counterparts. We use the location of galaxies in the projected velocity vs. position phase-space to separate our cluster sample into a region of objects accreted longer time ago and a region of recently accreted and infalling galaxies. We find a higher fraction of accreted metal-rich galaxies (63%) compared to the fraction of 28% of metal-rich galaxies in the infalling regions. Intermediate mass galaxies falling into the cluster for the first time are found to be in agreement with predictions of the fundamental metallicity relation. In contrast, for already accreted star-forming galaxies of similar masses, we find on average metallicities higher than predicted by the models. This trend is intensified for accreted cluster galaxies of the lowest mass bin, that display metallicities 2-3 times higher than predicted by models with primordial gas inflow. Environmental effects therefore strongly influence gas regulations and control gas metallicities of log(M/Msun)<10.2 (Salpeter IMF) cluster galaxies. We also investigate chemical evolutionary paths of model galaxies with and without inflow of gas showing that strangulation is needed to explain the higher metallicities of accreted cluster galaxies. Our results favor a strangulation scenario in which gas inflow stops for log(M/Msun)<10.2 galaxies when accreted by the cluster.Comment: Version better matched to the published version, including table with observed and derived quantities for the 76 cluster galaxie

The study of luminophores base influence activated by europium on their acid-base and luminescent properties

Five samples of luminophores, activated by europium and synthesized by sol-gel and СВС methods were investigated. The researched samples have basic surface character, differing depending on the base of luminophor and percentage of europium. Excitation and photoluminescent spectra were obtained. Photoluminescent spectrum of the samples, containing Eu(III) ions have the similar character. They have 5 stripes with maximum at 580, 598, 622, 658 nm and the doublet with stripes at 702 and 706 nm which are referred to innerconfigurational 4f-4f transits if europium ion 7F0-5D4. The samples YVPO4(P10):Eu8% and YVO4:Eu10% have the most intense luminescence. Their intensity is about 60 times higher than the YPO4:Eu10% sample has

Group 2 Innate Lymphoid Cells in Respiratory Allergic Inflammation

Millions of people worldwide are suffering from allergic inflammatory airway disorders. These conditions are regarded as a consequence of multiple imbalanced immune events resulting in an inadequate response with the exact underlying mechanisms still being a subject of ongoing research. Several cell populations have been proposed to be involved but it is becoming increasingly evident that group 2 innate lymphoid cells (ILC2s) play a key role in the initiation and orchestration of respiratory allergic inflammation. ILC2s are important mediators of inflammation but also tissue remodeling by secreting large amounts of signature cytokines within a short time period. Thereby, ILC2s instruct innate but also adaptive immune responses. Here, we will discuss the recent literature on allergic inflammation of the respiratory tract with a focus on ILC2 biology. Furthermore, we will highlight different therapeutic strategies to treat pulmonary allergic inflammation and their potential influence on ILC2 function as well as discuss the perspective of using human ILC2s for diagnostic purposes

Shock recovery experiments confirm the possibility of transferring viable microorganisms from Mars to Earth

Extract from introduction: With regard to the impact and ejection phase we tested the case for the transfer of microorganisms from Mars to Earth. Using a high explosive set-up thin layers of bacterial endospores of Bacillus subtilis, of the lichen Xanthoria elegans and of the cyanobacterium Chroococcidiopsis sp. embedded between two plates of gabbro were subjected to 10, 20, 30, 40 and 50 GPa which is the pressure range observed in Martian meteorites [1]