Palladio\u27s religious architecture in Venice

This thesis focuses on the three churches designed by the Renaissance architect Andrea Palladio in Venice: San Francesco della Vigna, San Giorgio Maggiore, and Il Redentore. Separate chapters devoted to each of these buildings explore multiple issues, among them Palladio’s awareness of the city, its civic rituals, and architectural traditions; his sources of inspiration in the buildings of classical antiquity, especially ancient Roman baths and temple façades; his relationship to the architecture of the recent past, especially in Venice but also on the terraferma; and his ability to adapt his style to suit the requirements of private, public, and monastic patrons. The thesis also examines Palladio’s innovative approaches to some of the most pressing issues of Renaissance church design, most notably the question of centralized vs. longitudinal planning, and the problem of what sort of façade should be placed before a typical church, with its high central nave flanked by lower aisles or chapel

Los establos de su majestad : Fernando Lorenzo y Alberto Rodríguez(h) : reconstrucción histórica de la puesta en escena

Recuperar las raíces artísticas y teatrales es valorar y consolidar la esencia de nuestras formas y necesidades de expresión. La reconstrucción histórica de Los establos de su Majestad, respondió al propósito de investigar los parámetros ideológicos, estructurales y metodológicos de un espectáculo local, inmerso en una época determinada por la presencia de fuertes y fieles ideales políticos y sociales. Se decidió entonces estudiar especialmente los procesos de búsqueda y gestación de la puesta en escena realizada por un grupo de hacedores teatrales que bregaron, en esta ocasión, por la denuncia y el desenmascaramiento de la verdad a través de su creación artística. Considerando siempre al hecho teatral como síntesis y reflejo de un hecho social.Fil: Fresina, María Mariana. Universidad Nacional de Cuy

Hydroxychloroquine for treatment of rheumatoid arthritis: multifocal electroretinogram and laser flare-cell photometry study

Stefano Sebastiani, Michela Fresina, Mauro Cellini, Emilio C Campos Department of Experimental, Diagnostic, and Specialty Medicine, Ophthalmology Service, University of Bologna, Bologna, Italy Purpose: To evaluate early changes in multifocal electroretinogram (mfERG) and subclinical aqueous humor flare and cellularity in patients receiving hydroxychloroquine (HCQ) as treatment for rheumatoid arthritis.Methods: Ten patients receiving treatment with HCQ and no ophthalmic symptoms were enrolled. After complete ocular examination, mfERG and laser flare-cell photometry were performed. Patients were also divided into two subgroups with HCQ cumulative dose (CD) higher or lower than 500 g. Results obtained were compared with a control group of ten healthy subjects and statistical analysis was performed.Results: In patients receiving HCQ treatment, mfERG P1-wave in ring 2 showed a significant reduction in amplitude and a significant increase in latency compared to healthy control subjects, respectively resulting in 1.143 µV vs 1.316 µV (P=0.040) and 38.611 ms vs 36.334 ms (P=0.024). These changes are highly related to CD. Furthermore, when using the laser flare-cell photometry, a significant increase in aqueous humor flare and cellularity was shown in patients with CD higher than 500 g, resulting in a mean value of 14.4 ph/ms compared to 8.1 ph/ms in patients with CD lower than 500 g (P=0.0029). These reports appear highly related to CD (P=0.001). Receiver operating characteristic curve analysis showed mfERG P1-wave amplitude in ring 2 as the most sensitive value in detecting early HCQ-related retinopathy.Conclusion: MfERG was shown to be a very sensitive test in detecting early retinal toxicity and should be used for the screening of patients receiving HCQ treatment. Although less sensitive, laser flare-cell photometry can provide further information to evaluate early toxic retinal cell damage. Keywords: hydroxychloroquine, multifocal electroretinography, laser flare-cell photometry, rheumatoid arthriti

Multitarget microangiopathy in a young healthy man with COVID-19 disease: A case report.

A 41‑year‑old man presented to the emergency department complaining of decrease of vision in his left eye. Initial examination was consistent with retrobulbar optic neuritis, and an intravenous drip of methylprednisolone was started. On the third day, the fundus examination revealed the appearance of multiple Purtscher‑like cotton‑wool spots in the posterior pole and nasally to the optic disc, slight retinal whitening around the fovea, and cherry‑red spot. The patient reported flu‑like symptoms, and he tested positive at PCR (polymerase chain reaction) test for 2019‑nCoV (2019 novel coronavirus) infection. Assuming possible 2019‑nCoV‑related vascular damage, we prescribed low‑molecular‑weight heparin. The lesions were regressing at follow‑up, and we registered a complete visual recovery

Quantitative Approach for the Analysis of Fusional Convergence Using Eye-Tracking and SacLab Toolbox

Fusional vergence is a disjunctive movement of the eyes that is made in order to obtain single vision. (e aim of the study was to provide a quantitative and objective approach for analyzing the fusional convergence response using eye tracking (ET) technology and automatic data analysis provided by the intuitive SacLab toolbox previously developed by our group. We evaluated the proposed approach in a population of 26 subjects with normal binocular vision, who were tested with base-out prisms (magnitudes 4\u394, 6\u394, and 10\u394) in order to elicit fusional convergence response. Eye movements were recorded using the Viewpoint ET and analyzed using SacLab. Parameters describing both the vergence and the version components of the fusional response (convergence duration, CD; peak convergence velocity, PCV; number of intrusive saccades, NS; and mean saccadic amplitude, MSA) were automatically calculated and provided to clinicians for an objective evaluation. Results showed that the number of subjects achieving fusional convergence decreased with prism magnitude. For subjects achieving fusion CD and PCV increased significantly (p < 0.05) when increasing the prism magnitude. For NS and MSA, there were no significant changes when passing to 6\u394, but a significant increase resulted when passing to 10\u394 (p < 0.05). Noninvasive ET associated with the intuitive SacLab toolbox may represent a valid option to objectively characterize the fusional vergence response in clinical setting. (e analysis may be extended to patients with vergence disorders

Epidemiology, clinical features, and surgical outcomes of acute acquired concomitant esotropia associated with myopia

Purpose: To analyze epidemiology, clinical features, and surgical outcomes of type III acute acquired concomitant esotropia (Bielschowsky esotropia (BE)). Methods: The medical charts of patients diagnosed with acquired concomitant esotropia between 2013 and 2021 were reviewed. Assessed data were age, gender, age at diplopia onset, age at the diagnosis, refraction, visual acuity, neuroimaging, diplopia onset, angle of deviation, stereopsis, surgical procedure, amount of surgery, and relapse of diplopia after surgery. Moreover, we investigated the correlation between the use of electronic devices and the onset of diplopia. Results: One hundred seventeen patients (mean age 35.07 ± 15.81 years) were included in the study. The mean delay to the diagnosis was 3.29 ± 3.62 years. Myopia range was 0 to 17 diopters spherical equivalent. 66,3% spent more than 4 hours a day using laptops, tablets, or smartphones at the onset of diplopia, and 90,6% presented a subacute onset. None showed neurologic signs or symptoms. Patients who underwent surgery were ninety-three, with a rate of surgical success of 93.6%, and a relapse rate of 17.2%. A negative correlation resulted between pre-operative deviation and age at diagnosis (ρ = -0.261; p<0.05), whereas factors associated with surgical failure were older age at diplopia onset (p = 0.042) and longer delay between onset and diagnosis (p = 0.002). Conclusion: We registered an outstanding increase in prevalence of BE, which could be related to the exponential increase in the use of electronic devices for professional, educational, and recreational purposes. A prompt diagnosis and an augmented dose of surgery allows good motor and sensory results

Symbolic meanings and e-learning in the workplace: The case of an intranet-based training tool

This article contributes to the debate on work-based e-learning, by unpacking the notion of ‘the learning context’ in a case where the mediating tool for training also supports everyday work. Users’ engagement with the information and communication technology tool is shown to reflect dynamic interactions among the individual, peer group, organizational and institutional levels. Also influential are professionals’ values and identity work, alongside their interpretations of espoused and emerging symbolic meanings. Discussion draws on pedagogically informed studies of e-learning and the wider organizational learning literature. More centrally, this article highlights the instrumentality of symbolic interactionism for e-learning research and explores some of the framework’s conceptual resources as applied to organizational analysis and e-learning design. </jats:p

L'historiographie linguistique à l'épreuve de l'étymologie ancienne

Fresina Claudio. L'historiographie linguistique à l'épreuve de l'étymologie ancienne. In: Archives et documents de la Société d'histoire et d'épistémologie des sciences du langage, Seconde série, n°3, 1990. pp. 93-115

De l’« interdiction » du lyrisme

« “Je pleure dans mon mouchoir, ou je m’y mouche”, et puis je montre, j’expose, je publie ce mouchoir, et voilà une page de poésie… ». Ainsi s’exprime Ponge au sujet de cette poésie subjective où l’acception effusive de « lyrique », déjà « horriblement fadasse » pour Rimbaud, est brutalement stigmatisée. Comment avoir envie de mettre son nez dans ce mouchoir, d y fouiller pour étudier de près ce lyrisme-là ? Cicéron n’avait-il pas déjà affirme, au dire de Sénèque, que, eût-il une deuxième vie..

Ocular-surface temperature modification by cataract surgery

none4noPurpose To analyze ocular-surface temperature changes after microincision cataract surgery and to correlate them with surgical, clinical, and laboratory parameters. Setting Ophthalmology Unit, Saint Orsola-Malpighi Hospital, Bologna, Italy. Design Prospective case series. Methods Patients affected by monolateral senile cataract were examined preoperatively and 7 days and 28 days postoperatively. Infrared thermography was used to measure the temperature soon after eye opening, the temperature after 10 seconds of sustained eye opening, and the difference between these 2 values in the central cornea, nasal limbus, and temporal limbus. The Ocular Surface Disease Index (OSDI), Schirmer test, vital staining, tear breakup time (TBUT), conjunctival scraping cytology, exudated tear-serum albumin, and laser flare–cell meter examinations were performed. Results The study comprised 26 patients (10 men, 16 women). The temperature changed significantly after surgery. The temperature soon after eye opening showed cooling in the central cornea and nasal limbus and heating in the temporal limbus. The temperature after 10 seconds of sustained eye opening minus the temperature soon after eye opening increased in all regions. The temperature after 10 seconds of sustained eye opening minus the temperature soon after eye opening in the central cornea was inversely related to the OSDI and directly related to TBUT. The temperature soon after eye opening increased in the temporal limbus and was directly related to inflammatory indices. Conclusions The ocular-surface temperature changed after cataract surgery depending on the region analyzed. The cooling in the central cornea could be related to the increased tear-film instability. The heating in the temporal limbus could be related to postoperative inflammation. Financial Disclosure None of the authors has a financial or proprietary interest in any material or method mentioned.openGiannaccare, Giuseppe; Fresina, Michela; Agnifili, Luca; Versura, PieraGiannaccare, Giuseppe; Fresina, Michela; Agnifili, Luca; Versura, Pier