3,354 research outputs found
Whose Ear (or Arm) to Bend? Information Sources and Venue Choice in Policy Making
Important conceptualizations of both interest groups and bureaucratic agencies suggest that these institutions provide legislatures with greater information for use in policy making. Yet little is known about how these information sources interact in the policy process as a whole. In this paper we consider this issue analytically, and develop a model of policy making in which multiple sources of information – from the bureaucracy, an interest group, or a legislature’s own in-house development – can be brought to bear on policy. Lobbyists begin this process by selecting a venue – Congress or a standing bureaucracy – in which to press for a policy change. The main findings of the paper are that self-selection of lobbyists into different policy making venues can be informative per se; that this self-selection can make legislatures willing to delegate more authority to ideologically distinct bureaucratic agents; and that delegation of authority, while it takes advantage of agency expertise, can nevertheless lead to an increase in the legislature’s own in-house information gathering (e.g., hearings). Changes within the Federal Trade Commission during the 1970s are reinterpreted in the context of our model.Delegation, Lobbying, Bureaucracy, Venue Choice, Discretion
Analysis of Writing Inks on Paper Using Direct Analysis in Real Time Mass Spectrometry
Ink analysis is central to questioned document examination. We applied direct analysis in real time mass spectrometry (DART MS) to ballpoint, gel, and fluid writing ink analysis. DART MS acquires the mass spectrum of an ink while it is still on a document without altering the appearance of the document. Spectra were acquired from ink on a variety of papers, and the spectrum of the blank paper could be subtracted out to produce a cleanly isolated ink spectrum in most cases. Only certain heavy or heavily processed papers interfered. The time since an ink is written on paper has a large effect on its spectrum. DART spectra change radically during the first few months after an ink is written as the more volatile components evaporate, but the spectra stabilize after that. A library-search study involving 166 well-aged inks assessed the ability to identify inks from their DART spectra. The aggregate success rate was 92%
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Complete response of skull base inverted papilloma to chemotherapy: Case report.
BackgroundInverted papilloma (IP) is the most common benign sinonasal neoplasm. Endoscopic techniques, improved understanding of pathophysiology, and novel surgical approaches have allowed rhinologists to treat IPs more effectively, with surgery being the mainstay of therapy. Frontal sinus IP poses a challenge for surgical therapy due to complex anatomy and potentially difficult surgical access.ObjectivesWe reported a unique case of a massive frontal sinus IP that presented with intracranial and orbital extension, with near resolution after chemotherapy.MethodsA retrospective case review of a patient with a frontal sinus IP treated at a tertiary academic medical center.ResultsA 75-year-old male patient presented with nasal obstruction, purulent nasal discharge, and a growing left supraorbital mass. Endoscopy demonstrated a mass that filled both frontal and ethmoid sinuses, with orbital invasion. There also was substantial erosion of the posterior table, which measured 1.73 Ă— 1.40 cm. A biopsy specimen demonstrated IP with carcinoma in situ. The patient was deemed unresectable on initial evaluation and, subsequently, underwent chemotherapy (carboplatin and paclitaxel). The tumor had a dramatic response to chemotherapy, and the patient elected for definitive surgery to remove any residual disease. During surgery, only a small focus of IP was found along the superior wall of the frontal sinus. No tumor was found elsewhere, including at the site of skull base erosion. The final pathology was IP without carcinoma in situ or dysplasia.ConclusionThis was the first reported case of chemotherapeutic "debulking" of IP, which facilitated surgical resection, despite substantial intracranial and orbital involvement. Although nearly all IPs can be treated surgically, rare cases, such as unresectable tumors, may benefit from systemic chemotherapy
Flight Test Results of an Axisymmetric Channeled Center Body Supersonic Inlet at Off-Design Conditions
Flight-testing of a channeled center-body axisymmetric supersonic inlet design concept was conducted at the National Aeronautics and Space Administration (NASA) Dryden Flight Research Center in collaboration with the NASA Glenn Research Center (Cleveland, Ohio) and TechLand Research, Inc. (North Olmsted, Ohio). This testing utilized the Propulsion Flight Test Fixture, flown on the NASA F-15B research test bed airplane (NASA tail number 836) at local experiment Mach numbers up to 1.50. The translating channeled center-body inlet was designed by TechLand Research, Inc. (U.S. Patent No. 6,276,632 B1) to allow for a novel method of off-design flow matching, with original test planning conducted under a NASA Small Business Innovative Research study. Data were collected in flight at various off-design Mach numbers for fixed-geometry representations of both the channeled center-body design and an equivalent area smooth center-body design for direct comparison of total pressure recovery and limited distortion measurements
Corporate Profitability and Competitive Circumstance
Among firms with income, profit on equity is generally greater for small firms than for large firms. The strong profit showing of small businesses is associated with higher sales/asset ratios than for large firms, higher debt/equity ratios, and higher realized losses. The authors conclude that differences in profitability among firms of different sizes are indicators of their differing competitive circumstances and of their differing contribution to industry development. These findings are based on cross-industry and intraindustry analysis of data from the Corporate Source Books of the Statistics of Income.
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