111 research outputs found
The YFM 2012 â Emerging Research and Established Needs: Fund Raising, Publishing and Career Advancement: SCNAT
Cultural animation in health research: An innovative methodology for patient and public involvement and engagement
Background
A significant challenge in Patient and Public Involvement and Engagement (PPIE) in health research is to include a wide range of opinions and experiences, including from those who repeatedly find themselves at the margins of society.
Objective
To contribute to the debate around PPIE by introducing a bottomâup methodology: cultural animation (CA). Cultural Animation is an artsâbased methodology of knowledge coâproduction and community engagement which employs a variety of creative and participatory exercises to help build trusting relationships between diverse participants (expert and nonâexperts) and democratize the process of research.
Design
Three CA fullâday workshops for the research project âA Picture of Health.â
Participants
Each workshop was attended by 20â25 participants including 4 academics, 5 retired health professionals who volunteered in the local community and 15 community members. Participants ranged in age from 25 to 75 years, and 80% of the participants were women over the age of 60.
Results
The CA workshops unearthed a diversity of hidden assets, increased human connectivity, led to rethinking of and coâcreating new health indicators and enabled participants to think of community health in a positive way and to consider what can be developed.
Discussion
Cultural animation encourages participants to imagine and create ideal pictures of health by experimenting with new ways of working together.
Conclusion
We conclude by highlighting the main advantages to PPIE as follows: CA provides a route to coâproduce research agendas, empowers the public to engage actively with health professionals and make a positive contribution to their community
Modular and Selective Arylation of Aryl Germanes (C-GeEt3 ) over C-Bpin, C-SiR3 and Halogens Enabled by Light-Activated Gold Catalysis.
Selective C sp 2 -C sp 2 couplings are powerful strategies for the rapid and programmable construction of bi- or multiaryls. To this end, the next frontier of synthetic modularity will likely arise from harnessing the coupling space that is orthogonal to the powerful Pd-catalyzed coupling regime. This report details the realization of this concept and presents the fully selective arylation of aryl germanes (which are inert under Pd0 /PdII catalysis) in the presence of the valuable functionalities C-BPin, C-SiMe3 , C-I, C-Br, C-Cl, which in turn offer versatile opportunities for diversification. The protocol makes use of visible light activation combined with gold catalysis, which facilitates the selective coupling of C-Ge with aryl diazonium salts. Contrary to previous light-/gold-catalyzed couplings of Ar-N2 + , which were specialized in Ar-N2 + scope, we present conditions to efficiently couple electron-rich, electron-poor, heterocyclic and sterically hindered aryl diazonium salts. Our computational data suggest that while electron-poor Ar-N2 + salts are readily activated by gold under blue-light irradiation, there is a competing dissociative deactivation pathway for excited electron-rich Ar-N2 + , which requires an alternative photo-redox approach to enable productive couplings
Understanding and design of organometallic reactivity with experimental and computational tools
Understanding and design of organometallic reactivity with experimental and computational tools
Ligand, Additive, and Solvent Effects in Palladium Catalysisâ:âMechanistic Studies En Route to Catalyst Design
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