410 research outputs found
The effect of pre-treatment psychoeducation on eating disorder pathology among patients with anorexia nervosa and bulimia nervosa
Pre-treatment psychoeducation can be effective for bulimic groups, but little is known about its effect on patients with anorexia nervosa. This study investigated the impact of a pre-treatment psychoeducational intervention on outpatients with diagnoses of full or atypical anorexia nervosa (N = 54) or bulimia nervosa/atypical eating disorder at a normal weight (N = 43). Each attended a four-session psychoeducational group whilst awaiting outpatient treatment. They completed measures of eating and personality disorder pathology pre-intervention, repeating the measures of eating pathology post-intervention. Effectiveness was tested for each diagnostic group using intention-to-treat analyses. Results confirm that such psychoeducational groups reduce unhealthy eating attitudes among bulimic patients, regardless of initial levels of eating and personality pathology. In contrast, the groups were not effective for anorexia nervosa sufferers. Such groups should be considered routinely during waiting periods for bulimia nervosa treatment, but further research is needed to determine how to help anorexia nervosa patients at this stage
In and out and out again: The travails of Brazil as a security provider in Africa
The story of Brazil as a contemporary security actor in Africa can prove a peculiar one. Marked by quick gains and an equally quick recognition over a short period of time, it has also been followed by an equally quick turnaround which has led, as of 2020, to a visible disengagement on the ground. We explore the main travails in this domain, which have compromised much of the gains previously obtained throughout the continent. The chapter begins with a general balance of the progress achieved between 2003 and 2016, followed by the highlights of the recent downturn. We then analyze a specific sub-area, namely, the inroads carried out at the defence industry level, in order to showcase the promises and contradictions often associated to what the country has offered across the Atlantic. We conclude by presenting some opportunities for a new pickup of Brazilian interest in the middle and long run
A phenomenological approach to the simulation of metabolism and proliferation dynamics of large tumour cell populations
A major goal of modern computational biology is to simulate the collective
behaviour of large cell populations starting from the intricate web of
molecular interactions occurring at the microscopic level. In this paper we
describe a simplified model of cell metabolism, growth and proliferation,
suitable for inclusion in a multicell simulator, now under development
(Chignola R and Milotti E 2004 Physica A 338 261-6). Nutrients regulate the
proliferation dynamics of tumor cells which adapt their behaviour to respond to
changes in the biochemical composition of the environment. This modeling of
nutrient metabolism and cell cycle at a mesoscopic scale level leads to a
continuous flow of information between the two disparate spatiotemporal scales
of molecular and cellular dynamics that can be simulated with modern computers
and tested experimentally.Comment: 58 pages, 7 figures, 3 tables, pdf onl
Radiative corrections to polarization observables in elastic electron-deuteron scattering in leptonic variables
The model--independent QED radiative corrections to polarization observables
in elastic scattering of unpolarized and longitudinally--polarized electron
beam by the deuteron target have been calculated in leptonic variables. The
experimental setup when the deuteron target is arbitrarily polarized is
considered and the procedure for applying derived results to the vector or
tensor polarization of the recoil deuteron is discussed. The basis of the
calculations consists of the account for all essential Feynman diagrams which
results in the form of the Drell-Yan representation for the cross-section and
use of the covariant parametrization of the deuteron polarization state. The
numerical estimates of the radiative corrections are given for the case when
event selection allows the undetected particles (photons and electron-positron
pairs) and the restriction on the lost invariant mass is used.Comment: 43 pages,3 figures. To be published in ZhTEF. revised 14.02.2012.
arXiv admin note: text overlap with arXiv:nucl-ex/0002003 by other author
From training to artisanal practice : rethinking choreographic relationships in modern dance
In the first part of the twentieth century early modern dancers created both a new art form and the forms of group social organisation that were its condition of possibility. This paper critically examines the balletic and disciplinary ‘training’ model of dancer formation and proposes that the assumption of training in dance can obscure other ways of understanding dance-making relationships and other values in early modern dance. An ‘artisanal’ mode of production and knowledge transmission based on a non-binary relationship between ‘master’ and apprentice and occurring in a quasi-domestic and personalised space of some intimacy is proposed as a more pertinent way to think the enabling conditions of modern dance creation
Crimmigration and Refugees: Bridging Visas, Criminal Cancellations and ‘Living in the Community’ as Punishment and Deterrence
Australia’s status as the only state with a policy of mandatory indefinite detention of all unlawful non-citizens, including asylum seekers, who are within Australian territory is a fact that is both well-known and frequently cited. From its inception, mandatory immigration detention was touted as ‘the method of deterrence for those seeking asylum onshore’ and since then ‘mandatory detention has been at the forefront of a deterrence as control and control as deterrence discourse’2. The imagined subjects of deterrence are frequently asylum seekers presented as ‘bogus’ or as economic migrants, and the sites for control are Australia’s ‘immigration program’ and borders. While these dual factors have animated the implementation and continuation of the policy for over 25 years, the contemporary practice and enforcement of detention in Australia presents a much more complex picture
Factors contributing to posttraumatic growth and its buffering effect in adult chidren of cancer patients undergoing treatment
This study examined relationships among demographic, clinical,
and psychosocial variables in adult children of cancer patients.
Two hundred and fourteen participants completed measures of
posttraumatic growth (PTG), distress, posttraumatic stress disorder
(PTSD) symptoms, social support, and family functioning. Significant
gender differences in all PTG dimensions were found, as well
as associations among PTG, gender, parental dependency, distress,
PTSD, and family functioning. Social support was not a mediator
in the relationship between gender and PTG. Gender, education,
disease duration, dependency, distress, and family flexibility predicted
PTG. Finally, PTG had amoderating effect in the relationship
between distress and PTSD/social support. These results may guide
psychosocial interventions in this population.Fundação para a Ciência e Tecnologia (FCT
Variation in mitochondrial function in hypoxia-sensitive and hypoxia-tolerant human glioma cells
We have shown previously that human glioblastoma multiforme cells vary in their ability to survive under hypoxic conditions. Under oxygen limiting conditions, hypoxia-tolerant cells decrease their oxygen consumption rate whereas hypoxia-sensitive cells continue to consume oxygen at a relatively steady rate until the oxygen supply becomes exhausted. We now show that hypoxia-tolerant and hypoxia-sensitive cells exhibit distinct patterns of mitochondrial function in response to hypoxic challenge. Hypoxia-tolerant cell lines retain stable mitochondrial membrane potential and ATP concentration when incubated under oxygen limiting conditions. In addition, hypoxia-tolerant cell lines are consistently more sensitive to a wide spectrum of inhibitors of mitochondrial function than are hypoxia-sensitive cells. In contrast, the hypoxia-sensitive cells are unable to maintain stable mitochondrial membrane potential and ATP levels when incubated at reduced oxygen tension. These results demonstrate significant differences in the mitochondrial function between these two phenotypes and reinforce previous data that suggest a regulatory role for mitochondria in the development of hypoxia tolerance
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