51 research outputs found

    Search for Truth: An Umpireal View

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    Search for Truth: An Umpireal View

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    Sentencing Guidelines: A Need for Creative Collaboration

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    Some Comments on Our Constitutionalized Adversary System by Monroe H. Freedman

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    Search for Truth: An Umpireal View

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    Runyon v. McCrary Should Not Be Overruled

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    I shall be arguing that in all the pertinent circumstances, Runyon v. McCrary should not be overruled unless it was grossly, utterly, and destructively wrong. Obviously, I believe no such demonstration is possible

    Finishing the euchromatic sequence of the human genome

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    The sequence of the human genome encodes the genetic instructions for human physiology, as well as rich information about human evolution. In 2001, the International Human Genome Sequencing Consortium reported a draft sequence of the euchromatic portion of the human genome. Since then, the international collaboration has worked to convert this draft into a genome sequence with high accuracy and nearly complete coverage. Here, we report the result of this finishing process. The current genome sequence (Build 35) contains 2.85 billion nucleotides interrupted by only 341 gaps. It covers ∼99% of the euchromatic genome and is accurate to an error rate of ∼1 event per 100,000 bases. Many of the remaining euchromatic gaps are associated with segmental duplications and will require focused work with new methods. The near-complete sequence, the first for a vertebrate, greatly improves the precision of biological analyses of the human genome including studies of gene number, birth and death. Notably, the human enome seems to encode only 20,000-25,000 protein-coding genes. The genome sequence reported here should serve as a firm foundation for biomedical research in the decades ahead

    In Memory of Monrad G. Paulsen

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    Search for Truth: An Umpireal View

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