Designing Situated Vocabularies to Counter Social Polarizations: A Case Study of Nolo Neighbourhood, Milan

Many neighbourhoods are currently serving as laboratories where new methods are being explored for collaboratively redesigning cities and tackling the social, environmental, and cultural issues affecting them. These redesign processes are often supported by local communities who increasingly develop bottom-up initiatives to innovate and preserve the neighbourhood’s "common goods." This is certainly the case of Nolo, an area in the city of Milan (Italy) that has recently undergone an urban regeneration process thanks to the presence of a proactive community of actors living and working in the neighbourhood. Despite effective social innovation practices enacted by part of the local community, several "voices" in Nolo - mainly belonging to marginalized communities - are still excluded from the current process of urban regeneration. This lack of attention is rather problematic for the whole community, as it is leading to increasing rather than mitigating social polarization. To address this issue, we approached Nolo and its community through a participatory design experimentation, generating a series of collaborative platforms to enable those marginalized voices - humans as well as non-humans - to be heard, to enter into agonistic conversations with one another, and to question what they (should) all care about. What this (still ongoing) experimentation is currently showing is that to co-design collaborative platforms to counter polarization needs to be carefully balanced, negotiating between all the actors involved and acknowledging their thick entanglements to finally unravel how they radically inter-depend on one another. This kind of "ontologizing" practice is currently proving to be pivotal to counter “antagonisms” (and, therefore, mitigate social polarizations), and re-framing them in "agonistic" terms. This article reports how we operated this “ontologizing” practice in a particularly debated area of the neighbourhood by embracing the perspective of marginalized actors, encouraging them to collaborative and transformative actions for their own situated context

La green economy in Emilia-Romagna: la sostenibilità come fattore di sviluppo

The aim of this work is to analyze the development of Green Economy in the Emilia-Romagna Region. Sustainability and efficiency are seen as springs of development to be pushed overall in a period of global economic crisis. Starting from the distinction of Green Production and Green Products, the authors have investigated the evolution of the sector in the last years, in particular analyzing the number of enterprises and products with environmental certifications and their economic performance. A special focus have been made regarding the production of Renewable Energy Sources and the EU objectives. Furthermore it has been explored the Agri-food sector, underlining its relationship with the environment and the threats given by Climate Change, and on the other side the opportunities linked to agro-energies and organic productions. The authors have made some on field interviews to operators and firms of different sector in order to better understand their perspective regarding Green Economy markets. Additionally to underline some strategic guidelines to be followed by governments to better implement structural changes to raise efficiency and to further green the economical production

Planning sustainable development of local productive systems: A methodological approach for the analyt-ical identification of Ecoregions

At the local and regional levels, planning for sustainable development rests on the structural peculiarities of territories following a development model that lays its foundations on the notion of the Marshallian industrial district. Recently, this form of production organization has been recognized as also featuring an organic agricultural sector, where the creation of ecoregions (or bio-districts) emphasizes the territorial dimension of sustainable development. Nevertheless, whilst ecoregions are acquiring substantial relevance at the international level, a comprehensive methodological approach for their analytical identification is still missing, thereby affecting the ability of policymakers to effectively identify territories suitable to enter an ecoregion. The few studies available on this topic adopt a narrow perspective when identifying ecoregions, considering only the dimensions that are strictly related to organic production and ignoring substantial variables that are able to capture the activities and elements that generate positive externalities and feed the economic, social and environmental life of a potential ecoregion. To fill this gap in the literature, this paper makes two innovative contributions. First, the paper discusses the notion of an ecoregion by stressing its relationship with other territorial features (i.e., environmental, social, and economic) that complement the agricultural dimensions. Second, the paper proposes a comprehensive methodological approach for the analytical identification of ecoregions considering not only the biological and agricultural features of territories but also crucial aspects related to their environmental, social and economic contexts. In this regard, the paper develops a new composite indicator, the Ecoregional Vocation Index (EVI) e to assess the vocation of territories to enter an ecoregion. As an illustrative example, the EVI is employed to analyse 29 municipalities belonging to the area of the Bologna Apennines (Emilia-Romagna region, Italy). The results of the analysis provide a ranking that classifies these municipalities from best to the worst in terms of their suitability to belong to an ecoregion. The results are presented and discussed to show how this methodological approach can be generally employed in sustainable territorial planning to support policymakers and other relevant stakeholders in the participatory processes concerning the creation of ecoregions

Cementless Total Hip Arthroplasty After an Iatrogenic Subtrochanteric Fracture due to Hardware Removal: A Case Report

Introduction: Total hip arthroplasty (THA) after proximal femoral fixation is a challenging procedure due to possible hardware-related complications. Case presentation: A 78-year-old female with hip osteoarthritis had a proximal femoral osteotomy fixed using a blade plate in the same femur 41 years ago. A two-step approach was planned. After a challenging hardware removal, an iatrogenic subtrochanteric fracture below the degenerated hip occurred after three months. THA with a tapered long stem was successfully performed with no need for additional osteosynthesis, and good results were seen two years later. Discussion: THAs in subtrochanteric fractures are technically demanding but feasible in selected cases. Hardware removal before THA implantation may carry important risks, and the surgical team should be prepared to perform arthroplasty in case of complications. Conclusion: THA in a subtrochanteric fracture below hip osteoarthritis is a feasible option in selected cases

Novel Bifunctional Amide-Based Initiator for the Atom Transfer Radical Polymerization of Styrene with Ascorbic Acid Acetonide as Reducing Agent

This study focuses on the synthesis and characterization of a new bifunctional benzamide initiator, CMB2HexDA, for the production of thermostable α,ω-dichloropolystyrene via ARGET ATRP. The motivation behind this research is the need to obtain functionalized polystyrene that can withstand the high temperatures used in industrial extrusion processes, as well as the previous development of a method to obtain α,ω-dialkenepolystyrene by solventless thermal dehydrohalogenation. The commonly used initiators in ATRP undergo thermal fragmentation, leading to chain length reduction and loss of telechelicity. The synthesized initiator was purified and characterized, and the resulting α,ω-dichloropolystyrenes were analyzed through GPC and NMR. The telechelic polystyrene produced with the new initiator exhibited enhanced thermal stability compared to aliphatic-halide ester initiators. Although the specific diamine used does not confer specific functionality, the developed synthetic pathway allows for the introduction of other functionalities into thermostable polystyrenes. Furthermore, the benzamidic function could be exploited to achieve controlled chemical degradation of polystyrene, resulting in more readly degradable oligomeric fragments

Innovation in the Solid Waste Management industry: integrating Neoclassical and Complexity Theory perspectives

Often considered a traditional labour intensive activity, in recent years, the solid waste management (SWM) industry has been largely interested in innovation. Nonetheless, the analysis of innovations in the SW industry is frequently confined to process innovation in the disposal segment, neglecting other kinds of innovation – such as product innovation and organizational innovation – in other segments. While several economic theoretical frameworks have been developed for interpreting eco-innovation in general, a specific analysis of innovation in each segment of SWM is still missing, despite the specificities of this sector. To fill this gap, this paper shows how complexity theory can be profitably used to integrate the more traditional neoclassical approach, offering a comprehensive theoretical framework to analyse innovation in the SWM industry from both a market and firm perspective (the neoclassical approach) and from a social perspective (the complexity theory framework). Four main typologies of the SW market system, exhibiting different kinds of innovation, are outlined: (i) a “traditional” landfill-oriented system; (ii) a modern “waste-to-energy” incinerator-oriented system; (iii) a “light recycling” system with integrated solutions and a selection performance that is lower than 50%; and (iv) a “hard recycling” system

\u3a0\u2011Stacking Signature in NMR Solution Spectra of Thiophene-Based Conjugated Polymers

Studies on conjugated polymers seldom report on their NMR characterization in solution. This paper shows how NMR experiments, both 1H NMR and routine 2D NMR spectra, can help in gaining a further insight into the aggregation behavior of conjugated polymers and could be used to flank the more employed solid-state NMR and other spectroscopy and microscopy techniques in the understanding of the aggregation processes. NMR spectroscopy allows distinguishing, within the class of poorly solvatochromic conjugated polymers, those highly prone to form \u3c0-stacked aggregates from the ones that have a low tendency toward \u3c0-stacking

A Trifunctional ATRP Initiator Bearing Adaptable Bonds

Atom Transfer Radical Polymerization (ATRP) allows for the production of polymers with precise control over molecular weight, dispersity, topology, composition, and functionality. Functional groups can be introduced into the polymer through post-functionalization of chain ends, or on the alkyl residue of the initiator, or by introducing functionalized (co)monomers, greatly greatly enhancing the targetable applications. In addition, the desired functional group can also be carried by the ATRP initiator. Some researchers have explored initiators with hydrolysis- or heat-sensitive functionalities to impart self-healing properties to the final polymer. However, the commonly used aliphatic halide ester initiators have shown poor thermal stability. To address this issue, we recently developed a novel bifunctional benzamide-containing initiator employed in ARGET ATRP of styrene, demonstrating enhanced thermal stability. Covalent Adaptable Networks (CANs) have emerged as a solution for improving the recyclability of thermoset materials. CANs can reorganize connectivity between chains upon thermal treatment, enabling reprocessing. Our goal is to modify the structure of the benzamide-containing initiator to develop a trifunctional initiator bearing adaptable bonds

Tumor growth rate to assess therapy response to immune-based combinations for metastatic renal cell carcinoma

Background: Radiological response assessment is becoming challenging with novel immune-based combinations for metastatic renal cell carcinoma (mRCC). RECIST criteria appear not exhaustively adequate to capture the kinetics of treatment response, which is better reflected by tumor growth rate (TGR). We explored TGR changes during first-line treatments and its association with clinical outcomes in mRCC. Research design and methods: We retrospectively evaluated TGR in untreated patients undergoing pembrolizumab/axitinib (P/A) or tyrosine-kinase inhibitors (TKI). TGR was calculated at the first (TGR1, after 3 months) and the second (TGR2, after 6 months) evaluation, thus assessing the TGR2-TGR1 difference. Results: Thirty-three patients were included (P/A n = 15, TKIs n = 18). Volumes firstly decreased more rapidly with TKIs, and then more slowly. Volumes initially remained stable with P/A, quickly decreasing until the second evaluation. TGR1 was related to progression-free survival (PFS; p = 0.023) and overall survival (p = 0.046) with P/A. TGR2 was correlated with PFS in all patients (p = 0.025). Patients with higher velocity volume reduction appeared to have improved survival benefits than patients with lower velocity considering both treatments, but especially with P/A. Conclusion: Combining immunotherapy with TKIs has an important role in enhancing the rapidity of tumor shrinkage. A rapid disease volume reduction correlates with better OS and PFS

Experimental calibration of underground heat transfer models under a winery building in a rural area

Ground temperature and hydrogeological conditions are key parameters for many engineering applications, such as the design of building basements and underground spaces and the assessment of shallow geothermal energy potential. Especially in urban areas, in the very shallow depths, it is diffi cult to fi nd natural undisturbed underground thermal conditions because of anthropic interventions. The assessment of underground behaviour in disturbed conditions will become more and more relevant because of increasing awareness to energy effi ciency and renewable energy topics. The purpose of this paper is to show a three-dimensional representation - based on models calibrated on experimental data - of the underground thermal behaviour aff ected by a building in a rural area in Italy. Temperature varies in space and time and it depends on ground, climate and building characteristics, and all these parameters are taken into account by the seasonal periodic modelling implemented. The results obtained in a context of low urbanization indirectly suggest the importance of these eff ects in dense urban areas; taking greater account of these aspects could lead to improvements in the design of underground spaces and geo-exchanger fi elds for geothermal energy exploitation