Knowledge Domains, Technological Strategies and Open Innovation

This study provides a patent-based framework, investigating the relationship among the relevance of the technological domains, the exploitation vs. exploration strategies and the choice of open innovation practices. Specifically, this work presents five levels of open innovation adoption and analyses the reason why firms open up their innovation boundaries. The methodology is tested on a sample of 240 companies belonging to the bio-pharmaceutical and the technology hardware & equipment industries, by examining their patents filed in 2011. Results show that the relevance of the knowledge domain affects the choice of the innovation strategy; also, non-equity alliances are preferred in explorative activities and equity alliances in exploitative ones

Patent data analysis of innovation behaviours in technology hardware & equipment industry

n/

Investments and Divestments of Intangibles in an Open Innovation Context

n/

Business Models for Open Innovation: From Collaboration to Incorporation

n/

Triple-Negative Breast Cancer comparison with Canine Mammary Tumors from light microscopy to molecular pathology

Many similar characteristics in human and dog cancers including, spontaneous development, clinical presentation, tumor heterogeneity, disease progression, and response to standard therapies have promoted the approval of this comparative model as an alternative to mice. Breast cancer represents the second most frequent neoplasm in humans after lung cancer. Triple-negative breast cancer (TNBC) constitute around 15% of all cases of breast cancer and do not express estrogen receptor (ER), progesterone receptor (PR) or overexpress human epidermal growth factor receptor 2 (HER2). Breast cancer is the second most frequent neoplasm in sexually intact female dogs after skin cancer. The majority of canine mammary tumors (CMTs) are triple-negative. Due to the high morphological, histologic, and molecular similarities between CMT and human breast cancers (HBC), human biomarkers of HBC are also observable in cases of CMT. Promising breast cancer biomarkers in both humans and canines are cancer-associated stroma (CAS), circulating tumor cells and tumor DNA (ctDNA) ), exosomes and miRNAs, and metabolites

Unexpected ovarian activity in premenopausal breast cancer survivors treated with exemestane and GnRH analogues

n/

The role of content management systems in publishing firms

This paper investigates the interaction between technological and organizational parameters. Recent studies have been focused on the information and communication impact on organizational parameters, owing to the growing need to acquire and process information. We focus on the impact of the content management system on publishing firms and through the study of ten Italian cases we identify the socio-technical context which favor the adoption of technology as well as the organizational parameters influenced by the technology use