Secondary SOLID Tumors after Allogeneic STEM CELL Transplantation: A CROSS-Sectional Evaluation in 260 Adults at 1-Year Follow-up

n/

Effects of robot-assisted training for the unaffected arm in patients with hemiparetic cerebral palsy: a proof-of-concept pilot study

On a voluntary basis, 10 adolescents with hemiparesis due to cerebral palsy and 11 neurologically healthy control subjects participated in this proof-of-concept pilot study. The aim was to examine the effects of robot-assisted training for the unaffected arm in patients with hemiparetic cerebral palsy. Baseline comparison between the unaffected arm of the hemiparetic patients with cerebral palsy and the dominant arm of healthy control subjects showed significant differences on the Jebsen-Taylor Hand Function test and action planning ability tests. Within-group comparison after ten 30-minute sessions (five days a week for two consecutive weeks) of robot-assisted training for the unaffected arm showed significant improvements in patients with cerebral palsy on the Jebsen-Taylor Hand Function test (performed at both hands) and action planning ability test (evaluated at the unaffected arm). Our findings are in line with previous evidences of action planning deficits at the unaffected arm in patients with hemiparetic cerebral palsy and support the hypothesis that robot-assisted training for the unaffected arm may be useful to improve manual dexterity and action planning in patients with hemiparesis due to cerebral palsy

Effects of Robot-Assisted Training for the Unaffected Arm in Patients with Hemiparetic Cerebral Palsy: A Proof-of-Concept Pilot Study

On a voluntary basis, 10 adolescents with hemiparesis due to cerebral palsy and 11 neurologically healthy control subjects participated in this proof-of-concept pilot study. The aim was to examine the effects of robot-assisted training for the unaffected arm in patients with hemiparetic cerebral palsy. Baseline comparison between the unaffected arm of the hemiparetic patients with cerebral palsy and the dominant arm of healthy control subjects showed significant differences on the Jebsen-Taylor Hand Function test and action planning ability tests. Within-group comparison after ten 30-minute sessions (five days a week for two consecutive weeks) of robot-assisted training for the unaffected arm showed significant improvements in patients with cerebral palsy on the Jebsen-Taylor Hand Function test (performed at both hands) and action planning ability test (evaluated at the unaffected arm). Our findings are in line with previous evidences of action planning deficits at the unaffected arm in patients with hemiparetic cerebral palsy and support the hypothesis that robot-assisted training for the unaffected arm may be useful to improve manual dexterity and action planning in patients with hemiparesis due to cerebral palsy

FLUIDODINAMICA (sez. ANEURISMI CEREBRALI cap. 8)

Opera indirizzata non solo agli specialisti, ma anche ai clinici: tecnica, fisiopatologia, clinica, competenze radiologiche e farmacologiche, linee guida, ragionamento e inquadramento clinico sono gli aspetti affrontati nel volume. La formazione interventistica neurovascolare non va esclusivamente rivolta all\u2019apprendimento delle tecniche d\u2019intervento: pertanto, ogni capitolo del libro \ue8 preceduto da nozioni di fisiopatologia e di clinica, in accordo con la visione di uno specialista non solo portatore di approfondite conoscenze neurovascolari, ma anche conoscitore delle funzioni cerebrali. Una rapida scorsa all\u2019indice spiegher\ue0 meglio di qualunque altra parola il contenuto e lo spirito di questo lavoro che i neuroradiologi italiani dedicano alla memoria del professor Massimo Gallucci e ai colleghi del futuro

ANEURISMI NON ROTTI (sez. ANEURISMI CEREBRALI cap. 7)

Opera indirizzata non solo agli specialisti, ma anche ai clinici: tecnica, fisiopatologia, clinica, competenze radiologiche e farmacologiche, linee guida, ragionamento e inquadramento clinico sono gli aspetti affrontati nel volume. La formazione interventistica neurovascolare non va esclusivamente rivolta all\u2019apprendimento delle tecniche d\u2019intervento: pertanto, ogni capitolo del libro \ue8 preceduto da nozioni di fisiopatologia e di clinica, in accordo con la visione di uno specialista non solo portatore di approfondite conoscenze neurovascolari, ma anche conoscitore delle funzioni cerebrali. Una rapida scorsa all\u2019indice spiegher\ue0 meglio di qualunque altra parola il contenuto e lo spirito di questo lavoro che i neuroradiologi italiani dedicano alla memoria del professor Massimo Gallucci e ai colleghi del futuro

Primary versus secondary mechanical thrombectomy for anterior circulation stroke in children: An update

This review of the literature on the use of mechanical thrombectomy (MT) in children with acute ischemic stroke from occlusion of the internal carotid artery and the proximal middle cerebral artery (MCA) compares the efficacy and safety of primary and secondary MT. We analyzed the data reported for 24 case reports from 20 relevant articles published up to 31 December 2016 and the data of a patient treated at our institution. Eighteen cases received primary MT and 7 received secondary MT. The proportions of complete MCA recanalization, small infarcts, and asymptomatic intracranial hemorrhage were similar in both MT groups (73% [11/15] vs. 67% [4/6], 58% [7/12] vs. 60% [3/5], and 15% [2/13] vs. 17% [1/6], respectively). The proportion of favorable neurological outcomes was higher for the primary MT group (69% [11/16] vs. 43% [3/7]). We found no substantial differences in efficacy and safety between primary and secondary MT for anterior circulation stroke in children

Resting state networks activity in euthymic Bipolar Disorder

OBJECTIVES: Bipolar disorder (BD) is a psychiatric condition causing shifts in mood, energy and activity levels severely altering the quality of life of the patients even in the euthymic phase. Although widely accepted, the neurobiological bases of the disorder in the euthymic phase remain elusive. This study aims at characterizing resting state functional activity of the BD euthymic phase in order to better understand the pathogenesis of the disease and build future neurobiological models. METHODS: Fifteen euthymic BD patients (10 females; mean age 40.2; standard deviation 13.5; range 20-61) and 27 healthy controls (HC) (21 females; mean age 37; standard deviation 10.6; range 22-60) underwent a 3T functional MRI scan at rest. Resting state activity was extracted through independent component analysis (ICA) run with automatic dimensionality estimation. RESULTS: ICA identified 22 resting state networks (RSNs). Within-network analysis revealed decreased connectivity in the visual, temporal, motor and cerebellar RSNs of BD patients versus HC. Between-network analysis showed increased connectivity between motor area and the default mode network (DMN) partially overlapping with the fronto-parietal network (FPN) in BD patients. CONCLUSION: Within-network analysis confirmed existing evidence of altered cerebellar, temporal, motor and visual networks in BD. Increased connectivity between the DMN and the motor area network suggests the presence of alterations of the fronto-parietal regions, precuneus and cingulate cortex in the euthymic condition. These findings indicate that specific connectivity alterations might persist even in the euthymic state suggesting the importance of examining both within and between-network connectivity to achieve a global understanding of the BD euthymic condition. This article is protected by copyright. All rights reserved

Triple Magnetic Resonance Angiography (triple-MRA) for confirmation of obliteration following Gamma Knife Radiosurgery for Arterial-Venous Malformations of the brain

no availabl