455 research outputs found

    Instructing Judges: Ethical Experience and Educational Technique

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    Most professional responsibility textbooks do not discuss judicial conduct, and not surprisingly, many judges find themselves unprepared for the ethical dilemmas they face when they make the transition from partisan advocate to neutral arbiter. Gray and Zemans discuss the nine-topic curriculum for judicial educators to use to teach judicial ethics to judges at programs for new judges, continuing judicial education courses and judicial conferences

    Instructing Judges: Ethical Experience and Educational Technique

    Get PDF
    Most professional responsibility textbooks do not discuss judicial conduct, and not surprisingly, many judges find themselves unprepared for the ethical dilemmas they face when they make the transition from partisan advocate to neutral arbiter. Gray and Zemans discuss the nine-topic curriculum for judicial educators to use to teach judicial ethics to judges at programs for new judges, continuing judicial education courses and judicial conferences

    Original habitation: pregnant flesh as absolute hospitality

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    The subject/object distinction in mystical experiencing

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    For human beings, consciousness is that which determines and constitutes the content, order and form of all of our experience. It is consciousness which generates our awareness as our own. Both experience and awareness provide the ontological basis to all that is possible for us. The conscious experience that we have - our thoughts, our feelings, our being aware of our existence in the world and our behaviour- either as isolatable goings-on, or in a more general everyday sense, can be divided into the rational and the intuitive. This is a rough division only, and is meant to represent the mediating or non-mediating role which consciousness plays in our experience, in terms of the structures which consciousness imposes to constitute the experience as it is. Generally speaking, rational experience is that which is bounded and constructed by the constraints of logic and language. Rational experience provides the framework within which nearly all of our thinking and behaving is manifested. At a very basic level this is seen in the simple stimulus/response mechanism with which we are all very familiar.(For example, when we are hungry, we know that the hunger can be satisfied by eating.) At a more sophisticated level, it is manifested in the complicated mental processes we might go through in order to solve a mathematical problem

    A temperate river estuary is a sink for methanotrophs adapted to extremes of pH, temperature and salinity

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    River Tyne (UK) estuarine sediments harbour a genetically and functionally diverse community of methane-oxidizing bacteria (methanotrophs), the composition and activity of which were directly influenced by imposed environmental conditions (pH, salinity, temperature) that extended far beyond those found in situ. In aerobic sediment slurries methane oxidation rates were monitored together with the diversity of a functional gene marker for methanotrophs (pmoA). Under near in situ conditions (4-30°C, pH 6-8, 1-15gl-1 NaCl), communities were enriched by sequences affiliated with Methylobacter and Methylomonas spp. and specifically a Methylobacter psychrophilus-related species at 4-21°C. More extreme conditions, namely high temperatures ≥40°C, high ≥9 and low ≤5 pH, and high salinities ≥35gl-1 selected for putative thermophiles (Methylocaldum), acidophiles (Methylosoma) and haloalkaliphiles (Methylomicrobium). The presence of these extreme methanotrophs (unlikely to be part of the active community in situ) indicates passive dispersal from surrounding environments into the estuary

    Interdisciplinary Perspectives on Mesmer and His Legacy: Literature, Culture, and Science

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    The second half of the eighteenth century saw the emergence of Franz Anton Mesmer's theories and therapies concerning the curative power of animal magnetism, an innate force that he claimed could be harnessed and directed to great healing effect. Formally dismissed by a French Royal Commission in 1784, the many positive treatment outcomes were attributed to the patient's own imagination. This acknowledgement by the scientific fraternity that imagination alone could effect cures signalled that Mesmer's work had uncovered new, exciting and even dangerous possibilities about the power of the mind. Always a controversial subject, those who chose to examine animal magnetism, or its later incarnations of mesmerism or hypnosis, were always at risk of social and professional criticism, even disgrace and exclusion, which raises the question of how and why respected members of the social and scientific community would approach this multifarious topic. By selecting as case studies three previously neglected figures in the mesmerism scholarship, namely, Ada Lovelace and two physician-writers, Santiago Ramón y Cajal and Arthur Conan Doyle, as well as incorporating a cutting-edge discussion of Mesmer's life, 'art', and complicated relationship with the scientific community, this thesis offers new perspectives through which to re-examine the complex phenomenon of mesmerism, its possible medical applicability, and the manifold literary representations it elicited. Drawing upon archival sources, scientific texts, letters, non-fictional and fictional works, this interdisciplinary study combines close textual analysis with an examination of scientific, social and cultural contexts. Through this pluralistic critical approach, and by seeking to understand the endurance of what may now be considered a protoscience rather than a pseudoscience, the thesis concludes that while Mesmer's work paved the way for a serious research into the constructs of the mind, the qualities of vision, observation and communication are essential to the re-evaluation of new ideas and their interpretation

    Cobaltocene-mediated catalytic monooxygenation using holo and heme domain cytochrome P450 BM3

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    The feasibility of replacing NADPH with 1,1′-dicarboxycobaltocene in the catalytic cycle of cytochrome P450 BM3 has been explored. Using the holoprotein, the surrogate mediator was observed to reduce both the FAD and FMN in the reductase domain, as well as the iron in the heme domain. In an electrochemical system, the mediator was able to support lauric acid hydroxylation at a rate of 16.5 nmol product/nmol enzyme/minute. Similar electron transfer and catalysis were observed for the heme domain alone in the presence of the metallocene; the turnover rate in this case was 1.8 nmol product/nmol enzyme/minute. Parallel studies under the same conditions using a previously reported cobalt sepulchrate mediator showed that the two systems give similar results for both the holoenzyme and the heme domain
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