640 research outputs found
What's the best way to motivate patients to exercise?
There is no single best strategy to motivate patients to exercise, given the lack of data from rigorous comparison studies. There are, however, several interventions for adults that are effective. They include: writing a patient-specific behavioral health ���green� prescription, encouraging patients to join forces with accountability partners or support groups, recommending the use of pedometers (strength of recommendation [SOR]: A, meta-analyses). In children and adolescents, multi-component strategies that include school-based interventions combined with either family or community involvement increase physical activity (SOR: A, systematic review)
Book Reviews [ October 2014]
Reviews of the following four recent books: The Muslims are coming!: Islamophobia, extremism and the domestic war on terror by Arun Kundnani reviewed by Nasima Hassan, Senior Lecturer, University of East London; Beyond early reading by David Waugh and Sally Neaum (eds.) reviewed by Fran Paffard, Senior Lecturer in Early Years and Primary Education, University of East London; Action research in education by Mary McAteer, reviewed by Adrian Copping, Senior Lecturer, University of Cumbria; and Leading professional practice in education by Christine Wise, Pete Bradshaw and Marion Cartwright (eds.), reviewed by Michele J. Burns, Deputy Headteacher, The Sandon School, Essex
Advances in methods for determining fecundity: application of the new methods to some marine fishes
17 pages, 9 figures, 6 tables.Estimation of individual
egg production (realized fecundity)
is a key step either to understand
the stock and recruit relationship
or to carry out fisheries-independent
assessment of spawning stock
biomass using egg production methods.
Many f ish are highly fecund
and their ovaries may weigh over a
kilogram; therefore the work time
can be consuming and require large
quantities of toxic fixative. Recently
it has been shown for Atlantic cod
(Gadus morhua) that image analysis
can automate fecundity determination
using a power equation that
links follicles per gram ovary to the
mean vitellogenic follicular diameter
(the autodiametric method).
In this article we demonstrate the
precision of the autodiametric method
applied to a range of species with different
spawning strategies during
maturation and spawning. A new
method using a solid displacement
pipette to remove quantitative fecundity
samples (25, 50, 100, and 200 milligram
[mg]) is evaluated, as are the
underlying assumptions to effectively
fix and subsample the ovary. Finally,
we demonstrate the interpretation of
dispersed formaldehyde-fixed ovarian
samples (whole mounts) to assess the
presence of atretic and postovulatory
follicles to replace labor intensive histology.
These results can be used to
estimate down regulation (production
of atretic follicles) of fecundity during
maturation.T his study was jointly funded under Eu ropean
Union Frame Work V Q5RS -2002 - 01825 and the
Institutes in England (Department of the Environment,
Food, and Rural Affairs), Norway (Institute
of Marine Research), and Spain (Consejo Superior
de Investigaciones Científ icas, and A ZTI Tecnalia
(publication number 424))Peer reviewe
A study of the significance of photoparoxysmal responses and spontaneous epileptiform discharges in the EEG in childhood epilepsy
Aim: In clinical practice, there is a prevailing notion that photosensitivity mostly occurs in children with epilepsy (CWE) with idiopathic generalized epilepsy. We investigated the distribution of epilepsy types and etiology in photosensitive children and the associations with specific clinical and electroencephalogram (EEG) variables. Methods: In this retrospective cohort study, clinical data were acquired from all children that showed photosensitivity during systematic intermittent photic stimulation (IPS), over a 10-year interval at a tertiary level Children\u27s Hospital, Winnipeg. Patient demographics, EEG findings, and clinical data and symptoms during IPS were abstracted. Classification of diagnoses using the International League Against Epilepsy (ILAE) 2017 guidelines was done by an expert panel. Results: Seventy-eight photosensitive children were identified. Forty (51.3%) had generalized epilepsy (idiopathic: 27, structural: 2, other: 11) compared with 19 (24.4%) focal (idiopathic: 1, structural: 2, other: 16), 8 (10.3%) combined focal and generalized (structural: 4, other: 4), and 11 (14.1%) unknown epilepsy (other: 11); (χ2 (3) = 32.1, p = .000). Self-sustaining or outlasting photoparoxysmal responses (PPRs) occurred in association with all epilepsy types; however, the EEGs of focal CWE without treatment comprised almost solely of PPRs which outlasted the stimulus (8/10), in contrast to only 8/17 of focal CWE with treatment and to 13/26 of generalized epilepsy without treatment. Most frequency intervals in individual patients were less under treatment: a decrease in standardized photosensitivity range (SPR) was seen in 5 CWE, an increase in 2, and no change in 1 during treatment. Both CWE with focal and generalized epilepsy showed abnormal activity on EEG during hyperventilation (40% vs 65.7%). Thirteen out of 14 CWE with clinical signs during IPS had independent spontaneous epileptiform discharges (SEDs) in the EEG recording. Conclusion: Photosensitivity occurs in all types of epilepsy rather than in idiopathic generalized epilepsy alone. Surprisingly, there is a tendency for focal epilepsy to be associated with self-sustaining PPRs, especially when no treatment is used. Treatment tends to make the PPR more self-limiting and decrease the SPR. There is a tendency that clinical signs during IPS occur in EEGs in individuals with SEDs
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