140 research outputs found
Coverage and equity in reproductive and maternal health interventions in Brazil:Impressive progress following the implementation of the Unified Health System
Distrofia Miotônica Tipo 1: Frequência Dos Achados Oftalmológicos
The purpose of the study was to evaluate the frequency of ophthalmologic abnormalities in a cohort of myotonic dystrophy type 1 (DM1) patients and to correlate them with motor function. We reviewed the pathophysiology of cataract and low intraocular pressure (IOP). Method: Patients were included after clinical and laboratory diagnosis and after signed informed consent. They were evaluated by Motor Function Measure scale, Portuguese version (MFM-P) and ophthalmic protocol. Results: We evaluated 42 patients aged 17 to 64 years (mean 40.7 ± 12.5), 22 of which were men. IOP (n = 41) was reduced in all but one. We found cataract or positivity for surgery in 38 (90.48%) and ptosis in 23 (54.76%). These signs but not IOP were significantly correlated with severity of motor dysfunction. Abnormalities in ocular motility and stereopsis were observed. Conclusion: Cataract and ptosis are frequent in DM1 and associated to motor dysfunction. Reduced IOP is also common, but appears not to be related with motor impairment. © 2016, Associacao Arquivos de Neuro-Psiquiatria. All rights reserved.74318318
Conceitos Atuais No Tratamento Das Ataxias Hereditárias
Hereditary ataxias (HA) represents an extensive group of clinically and genetically heterogeneous neurodegenerative diseases, characterized by progressive ataxia combined with extra-cerebellar and multi-systemic involvements, including peripheral neuropathy, pyramidal signs, movement disorders, seizures, and cognitive dysfunction. There is no effective treatment for HA, and management remains supportive and symptomatic. In this review, we will focus on the symptomatic treatment of the main autosomal recessive ataxias, autosomal dominant ataxias, X-linked cerebellar ataxias and mitochondrial ataxias. We describe management for different clinical symptoms, mechanismbased approaches, rehabilitation therapy, disease modifying therapy, future clinical trials and perspectives, genetic counseling and preimplantation genetic diagnosis. © 2016, Associacao Arquivos de Neuro-Psiquiatria. All rights reserved.74324425
Derek Denny-brown: O Homem Por Detrás Dos Gânglios
The authors present an historical review about the main contributions of Professor Derek Denny-Brown to neurology. Some of his achievements include the first description of sensory neuronopathies, and some of the essential textbooks on the function and anatomy of the basal ganglia. In 2016, on the 35th anniversary of his death, modern neurologists are still strongly influenced by his legacy. © 2017, Associacao Arquivos de Neuro-Psiquiatria. All rights reserved.75212712
Meningite crônica, hidrocefalia e paraplegia medular em histoplasmose não-sistêmica
[No abstract available]sem informação746514515sem informaçãosem informaçã
Quantifying the decay of quantum properties in single-mode states
The dissipative dynamics of Gaussian squeezed states (GSS) and coherent
superposition states (CSS) are analytically obtained and compared. Time scales
for sustaining different quantum properties such as squeezing, negativity of
the Wigner function or photon number distribution are calculated. Some of these
characteristic times also depend on initial conditions. For example, in the
particular case of squeezing, we find that while the squeezing of CSS is only
visible for small enough values of the field intensity, in GSS it is
independent of this quantity, which may be experimentally advantageous. The
asymptotic dynamics however is quite similar as revealed by the time evolution
of the fidelity between states of the two classes.Comment: Accepted versio
Mixedness and entanglement for two-mode Gaussian states
We analytically exploit the two-mode Gaussian states nonunitary dynamics. We
show that in the zero temperature limit, entanglement sudden death (ESD) will
always occur for symmetric states (where initial single mode compression is
) provided the two mode squeezing satisfies We also give the analytical expressions for the time of ESD.
Finally, we show the relation between the single modes initial impurities and
the initial entanglement, where we exhibit that the later is suppressed by the
former.Comment: Accepted for publication in Optics Communication
Inequalities in full immunization coverage:Trends in low-and middle-income countries
OBJECTIVE: To investigate disparities in full immunization coverage across and within 86 low- and middle-income countries. METHODS: In May 2015, using data from the most recent Demographic and Health Surveys and Multiple Indicator Cluster Surveys, we investigated inequalities in full immunization coverage – i.e. one dose of bacille Calmette-Guérin vaccine, one dose of measles vaccine, three doses of vaccine against diphtheria, pertussis and tetanus and three doses of polio vaccine – in 86 low- or middle-income countries. We then investigated temporal trends in the level and inequality of such coverage in eight of the countries. FINDINGS: In each of the World Health Organization’s regions, it appeared that about 56–69% of eligible children in the low- and middle-income countries had received full immunization. However, within each region, the mean recorded level of such coverage varied greatly. In the African Region, for example, it varied from 11.4% in Chad to 90.3% in Rwanda. We detected pro-rich inequality in such coverage in 45 of the 83 countries for which the relevant data were available and pro-urban inequality in 35 of the 86 study countries. Among the countries in which we investigated coverage trends, Madagascar and Mozambique appeared to have made the greatest progress in improving levels of full immunization coverage over the last two decades, particularly among the poorest quintiles of their populations. CONCLUSION: Most low- and middle-income countries are affected by pro-rich and pro-urban inequalities in full immunization coverage that are not apparent when only national mean values of such coverage are reported
Realistic Equations of State for the Primeval Universe
Early universe equations of state including realistic interactions between
constituents are built up. Under certain reasonable assumptions, these
equations are able to generate an inflationary regime prior to the
nucleosynthesis period. The resulting accelerated expansion is intense enough
to solve the flatness and horizon problems. In the cases of curvature parameter
\kappa equal to 0 or +1, the model is able to avoid the initial singularity and
offers a natural explanation for why the universe is in expansion.Comment: 32 pages, 5 figures. Citations added in this version. Accepted EPJ
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