Nitrogen fluorescence in air for observing extensive air showers

Extensive air showers initiate the fluorescence emissions from nitrogen molecules in air. The UV-light is emitted isotropically and can be used for observing the longitudinal development of extensive air showers in the atmosphere over tenth of kilometers. This measurement technique is well-established since it is exploited for many decades by several cosmic ray experiments. However, a fundamental aspect of the air shower analyses is the description of the fluorescence emission in dependence on varying atmospheric conditions. Different fluorescence yields affect directly the energy scaling of air shower reconstruction. In order to explore the various details of the nitrogen fluorescence emission in air, a few experimental groups have been performing dedicated measurements over the last decade. Most of the measurements are now finished. These experimental groups have been discussing their techniques and results in a series of Air Fluorescence Workshops commenced in 2002. At the 8$^{\rm{th}}$ Air Fluorescence Workshop 2011, it was suggested to develop a common way of describing the nitrogen fluorescence for application to air shower observations. Here, first analyses for a common treatment of the major dependences of the emission procedure are presented. Aspects like the contributions at different wavelengths, the dependence on pressure as it is decreasing with increasing altitude in the atmosphere, the temperature dependence, in particular that of the collisional cross sections between molecules involved, and the collisional de-excitation by water vapor are discussed.Comment: 12 pages, 17 figures, 2 tables, International Symposium on Future Directions in UHECR Physics, 13-16 February 2012, CERN, Geneva (Switzerland); the updated version corrects for a typo in Eq. (1

Nucleation of quark matter in protoneutron star matter

The phase transition from hadronic to quark matter may take place already during the early post-bounce stage of core collapse supernovae when matter is still hot and lepton rich. If the phase transition is of first order and exhibits a barrier, the formation of the new phase occurs via the nucleation of droplets. We investigate the thermal nucleation of a quark phase in supernova matter and calculate its rate for a wide range of physical parameters. We show that the formation of the first droplet of a quark phase might be very fast and therefore the phase transition to quark matter could play an important role in the mechanism and dynamics of supernova explosions.Comment: v3: fits version published in Physical Review

Phase conversion in a weakly first-order quark-hadron transition

We investigate the process of phase conversion in a thermally-driven {\it weakly} first-order quark-hadron transition. This scenario is physically appealing even if the nature of this transition in equilibrium proves to be a smooth crossover for vanishing baryonic chemical potential. We construct an effective potential by combining the equation of state obtained within Lattice QCD for the partonic sector with that of a gas of resonances in the hadronic phase, and present numerical results on bubble profiles, nucleation rates and time evolution, including the effects from reheating on the dynamics for different expansion scenarios. Our findings confirm the standard picture of a cosmological first-order transition, in which the process of phase conversion is entirely dominated by nucleation, also in the case of a weakly first-order transition. On the other hand, we show that, even for expansion rates much lower than those expected in high-energy heavy ion collisions, nucleation is very unlikely, indicating that the main mechanism of phase conversion is spinodal decomposition. Our results are compared to those obtained for a strongly first-order transition, as the one provided by the MIT bag model.Comment: 12 pages, 10 figures; v2: 1 reference added, minor modifications, matches published versio

Suitability of salivary leucocytes to assess DNA repair ability in human biomonitoring studies by the challenge-comet assay

The challenge-comet assay is a simple but effective approach that provides a quantitative and functional determination of DNA repair ability, and allows to monitor the kinetics of repair process. Peripheral blood mononuclear cells (PBMC) are the cells most frequently employed in human biomonitoring studies using the challenge-comet assay, but having a validated alternative of non-invasive biomatrix would be highly convenient for certain population groups and circumstances. The objective of this study was to validate the use of salivary leucocytes in the challenge-comet assay. Leucocytes were isolated from saliva samples and challenged (either in fresh or after cryopreservation) with three genotoxic agents acting by different action mechanisms: bleomycin, methyl methanesulfonate, and ultraviolet radiation. Comet assay was performed just after treatment and at other three additional time points, in order to study repair kinetics. The results obtained demonstrated that saliva leucocytes were as suitable as PBMC for assessing DNA damage of different nature that was efficiently repaired over the evaluated time points, even after 5 months of cryopreservation (after a 24 h stimulation with PHA). Furthermore, a new parameter to determine the efficacy of the repair process, independent of the initial amount of damage induced, is proposed, and recommendations to perform the challenge-comet assay with salivary leucocytes depending on the type of DNA repair to be assessed are suggested. Validation studies are needed to verify whether the method is reproducible and results reliable and comparable among laboratories and studies. © 2022 The AuthorsFunding text 1: This work was funded by the Spanish Ministry of Science and Innovation : MCIN/AEI/10.13039/501100011033 (Grants PID2020-113788RB-I00 and PID2020-114908 GA-I00 ), NanoBioBarriers project (PTDC/MED-TOX/31162/2017), Xunta de Galicia (ED431B 2022/16), co-financed by the Operational Program for Competitiveness and Internationalization (POCI) through European Regional Development Funds ( FEDER / FNR ), Spanish Ministry of Education, Culture and Sport [ BEAGAL18/00142 to V.V.], and Spanish Ministry of Economy and Competitiveness , co-financed by the European Social Fund [ RYC-2015-18394 to L.L,-L,]. Funding for open access charge: Universidade da Coruña/CISUG. ; Funding text 2: This work was funded by the Spanish Ministry of Science and Innovation: MCIN/AEI/10.13039/501100011033 (Grants PID2020-113788RB-I00 and PID2020-114908 GA-I00), NanoBioBarriers project (PTDC/MED-TOX/31162/2017), Xunta de Galicia (ED431B 2022/16), co-financed by the Operational Program for Competitiveness and Internationalization (POCI) through European Regional Development Funds (FEDER/FNR), Spanish Ministry of Education, Culture and Sport [BEAGAL18/00142 to V.V.], and Spanish Ministry of Economy and Competitiveness, co-financed by the European Social Fund [RYC-2015-18394 to L.L,-L,]. Funding for open access charge: Universidade da Coruña/CISUG

The Role of Strangeness in Astrophysics - an Odyssey through Strange Phases

The equation of state for compact stars is reviewed with special emphasis on the role of strange hadrons, strange dibaryons and strange quark matter. Implications for the properties of compact stars are presented. The importance of neutron star data to constrain the properties of hypothetic particles and the possible existence of exotic phases in dense matter is outlined. We also discuss the growing interplay between astrophysics and heavy-ion physics.Comment: invited talk given at Strange Quark Matter 2001, Frankfurt, Germany, 8 pages, uses iopart.cls, minor modifications, version to appear in J. Phys.

Strangeness in Astrophysics and Cosmology

Some recent developments concerning the role of strange quark matter for astrophysical systems and the QCD phase transition in the early universe are addressed. Causality constraints of the soft nuclear equation of state as extracted from subthreshold kaon production in heavy-ion collisions are used to derive an upper mass limit for compact stars. The interplay between the viscosity of strange quark matter and the gravitational wave emission from rotation-powered pulsars are outlined. The flux of strange quark matter nuggets in cosmic rays is put in perspective with a detailed numerical investigation of the merger of two strange stars. Finally, we discuss a novel scenario for the QCD phase transition in the early universe, which allows for a small inflationary period due to a pronounced first order phase transition at large baryochemical potential.Comment: 8 pages, invited talk given at the International Conference on Strangeness in Quark Matter (SQM2009), Buzios, Brasil, September 28 - October 2, 200

Increasing prevalence of obesity and diabetes among patients evaluated for liver transplantation in a Swiss tertiary referral center: a 10-year retrospective analysis.

Non-alcoholic fatty liver disease (NAFLD) is now the first cause of chronic liver disease in developed countries. We aimed to assess trends in the prevalence of obesity, type 2 diabetes mellitus (T2DM) and NAFLD in patients undergoing liver transplantation evaluation and to assess whether obese patients were less likely to be listed or had an increased drop-out rate after listing. We conducted a retrospective study of all consecutive patients who underwent liver transplantation evaluation at a Swiss tertiary referral centre between January 2009 and March 2020. A total of 242 patients were included, 83% were male. The median age was 59 years (IQR, 51-64 years). The most common causes of end-stage liver disease were viral hepatitis (28%), alcoholic liver disease (21%) and NAFLD (12%). Obesity was present in 28% of our cohort, with a significant increase over time. Prevalence of type 2 diabetes mellitus followed the same trend (p = 0.02). The proportions of non-listed and listed obese patients did not differ (21% vs. 30% respectively; p = 0.3). The prevalence of obesity and type 2 diabetes mellitus significantly increased over our study period. Obese patients had similar chances of being listed. The landscape of liver transplantation indications is shifting towards NAFLD, highlighting the urgent need to prevent NAFLD progression

Magnetic Catalysis: A Review

We give an overview of the magnetic catalysis phenomenon. In the framework of quantum field theory, magnetic catalysis is broadly defined as an enhancement of dynamical symmetry breaking by an external magnetic field. We start from a brief discussion of spontaneous symmetry breaking and the role of a magnetic field in its a dynamics. This is followed by a detailed presentation of the essential features of the phenomenon. In particular, we emphasize that the dimensional reduction plays a profound role in the pairing dynamics in a magnetic field. Using the general nature of underlying physics and its robustness with respect to interaction types and model content, we argue that magnetic catalysis is a universal and model-independent phenomenon. In support of this claim, we show how magnetic catalysis is realized in various models with short-range and long-range interactions. We argue that the general nature of the phenomenon implies a wide range of potential applications: from certain types of solid state systems to models in cosmology, particle and nuclear physics. We finish the review with general remarks about magnetic catalysis and an outlook for future research.Comment: 37 pages, to appear in Lect. Notes Phys. "Strongly interacting matter in magnetic fields" (Springer), edited by D. Kharzeev, K. Landsteiner, A. Schmitt, H.-U. Yee. Version 2: references adde

Dense quark matter in compact stars

The densest predicted state of matter is colour-superconducting quark matter, in which quarks near the Fermi surface form a condensate of Cooper pairs. This form of matter may well exist in the core of compact stars, and the search for signatures of its presence is an ongoing enterprise. Using a bag model of quark matter, I discuss the effects of colour superconductivity on the mass-radius relationship of compact stars, showing that colour superconducting quark matter can occur in compact stars at values of the bag constant where ordinary quark matter would not be allowed. The resultant ``hybrid'' stars with colour superconducting quark matter interior and nuclear matter surface have masses in the range 1.3-1.6 Msolar and radii 8-11 km. Once perturbative corrections are included, quark matter can show a mass-radius relationship very similar to that of nuclear matter, and the mass of a hybrid star can reach 1.8 \Msolar.Comment: 11 pages, for proceedings of SQM 2003 conference; references added, abstract reworde