29,936 research outputs found
Linkages in thermal copolymers of lysine
The thermal copolymerization of lysine with other alpha-amino acids was studied. The identity of the second amino acid influences various properties of the polymer obtained, including the proportion of alpha and epsilon linkages of lysine. A review of linkages in proteinoids indicates alpha and beta linkages for aspartic acid, alpha and gamma linkages for glutamic acid, alpha and epsilon linkages for lysine, and alpha linkages for other amino acids. Thermal proteinoids are thus more complex in types of linkage than are proteins
A study of optimum cowl shapes and flow port locations for minimum drag with effective engine cooling, volume 2
The listings, user's instructions, sample inputs, and sample outputs of two computer programs which are especially useful in obtaining an approximate solution of the viscous flow over an arbitrary nonlifting three dimensional body are provided. The first program performs a potential flow solution by a well known panel method and readjusts this initial solution to account for the effects of the boundary layer displacement thickness, a nonuniform but unidirectional onset flow field, and the presence of air intakes and exhausts. The second program is effectually a geometry package which allows the user to change or refine the shape of a body to satisfy particular needs without a significant amount of human intervention. An effort to reduce the cruise drag of light aircraft through an analytical study of the contributions to the drag arising from the engine cowl shape and the foward fuselage area and also that resulting from the cooling air mass flowing through intake and exhaust sites on the nacelle is presented. The programs may be effectively used to determine the appropriate body modifications or flow port locations to reduce the cruise drag as well as to provide sufficient air flow for cooling the engine
Automated design of minimum drag light aircraft fuselages and nacelles
The constrained minimization algorithm of Vanderplaats is applied to the problem of designing minimum drag faired bodies such as fuselages and nacelles. Body drag is computed by a variation of the Hess-Smith code. This variation includes a boundary layer computation. The encased payload provides arbitrary geometric constraints, specified a priori by the designer, below which the fairing cannot shrink. The optimization may include engine cooling air flows entering and exhausting through specific port locations on the body
Multi-filter transit observations of WASP-39b and WASP-43b with three San Pedro M\'artir telescopes
Three optical telescopes located at the San Pedro M\'artir National
Observatory were used for the first time to obtain multi-filter defocused
photometry of the transiting extrasolar planets WASP-39b and WASP-43b. We
observed WASP-39b with the 2.12m telescope in the U filter for the first time,
and additional observations were carried out in the R and I filters using the
0.84m telescope. WASP-43b was observed in VRI with the same instrument, and in
the i filter with the robotic 1.50m telescope. We reduced the data using
different pipelines and performed aperture photometry with the help of custom
routines, in order to obtain the light curves. The fit of the light curves
(1.5--2.5mmag rms), and of the period analysis, allowed a revision of the
orbital and physical parameters, revealing for WASP-39b a period ( days) which is seconds larger than
previously reported. Moreover, we find for WASP-43b a planet/star radius
() which is larger in the i filter
with respect to previous works, and that should be confirmed with additional
observations. Finally, we confirm no evidence of constant period variations in
WASP-43b.Comment: 13 pages, 7 figures, accepted in PASP, scheduled for the February 1,
2015 issu
Infant cortex responds to other humans from shortly after birth
A significant feature of the adult human brain is its ability to selectively process information about conspecifics. Much debate has centred on whether this specialization is primarily a result of phylogenetic adaptation, or whether the brain acquires expertise in processing social stimuli as a result of its being born into an intensely social environment. Here we study the haemodynamic response in cortical areas of newborns (1–5 days old) while they passively viewed dynamic human or mechanical action videos. We observed activation selective to a dynamic face stimulus over bilateral posterior temporal cortex, but no activation in response to a moving human arm. This selective activation to the social stimulus correlated with age in hours over the first few days post partum. Thus, even very limited experience of face-to-face interaction with other humans may be sufficient to elicit social stimulus activation of relevant cortical regions
Building the Brazilian Academic Genealogy Tree
Along the history, many researchers provided remarkable contributions to
science, not only advancing knowledge but also in terms of mentoring new
scientists. Currently, identifying and studying the formation of researchers
over the years is a challenging task as current repositories of theses and
dissertations are cataloged in a decentralized way through many local digital
libraries. Following our previous work in which we created and analyzed a large
collection of genealogy trees extracted from NDLTD, in this paper we focus our
attention on building such trees for the Brazilian research community. For
this, we use data from the Lattes Platform, an internationally renowned
initiative from CNPq, the Brazilian National Council for Scientific and
Technological Development, for managing information about individual
researchers and research groups in Brazil
Anthropic Explanation of the Dark Matter Abundance
I use Bousso's causal diamond measure to make a statistical prediction for
the dark matter abundance, assuming an axion with a large decay constant f_a >>
10^{12} GeV. Using a crude approximation for observer formation, the prediction
agrees well with observation: 30% of observers form in regions with less dark
matter than we observe, while 70% of observers form in regions with more dark
matter. Large values of the dark matter ratio are disfavored by an elementary
effect: increasing the amount of dark matter while holding fixed the baryon to
photon ratio decreases the number of baryons inside one horizon volume. Thus
the prediction is rather insensitive to assumptions about observer formation in
universes with much more dark matter than our own. The key assumption is that
the number of observers per baryon is roughly independent of the dark matter
ratio for ratios near the observed value.Comment: 10 pages; v3: published version, references adde
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Time-trends and treatment gaps in the antithrombotic management of patients with atrial fibrillation after percutaneous coronary intervention: Insights from the CHUM AF-STENT Registry.
BACKGROUND: The management of atrial fibrillation and flutter (AF) patients undergoing percutaneous coronary intervention (PCI) has undergone a rapid recent evolution. In 2016, the Canadian Cardiovascular Society (CCS) published expert recommendations to help guide clinicians in balancing bleeding and thrombotic risks in these patients. HYPOTHESIS: Antithrombotic regimen prescriptions for AF patients undergoing PCI evolved after the publication of the 2016 CCS AF guidelines. METHODS: A prospective cohort of AF patients undergoing PCI with placement of a coronary stent from a single tertiary academic center was analyzed for the recommended antithrombotic regimen at discharge. Prescribing behavior was compared between three time periods (Cohort A [2010-2011]; Cohort B [2014-2015]; Cohort C [2017]) using the χ2 test. In addition, antithrombotic management in Cohorts B and C were compared to guideline-recommended therapy. RESULTS: A total of 459 patients with AF undergoing PCI were identified. Clinical and procedural characteristics were similar between cohorts, with the exception of an increase in drug-eluting stent (DES) use over time (P < .01). Overall, the rate of oral anticoagulation (OAC) increased over time (P < .01), associated with an increase in nonvitamin K OAC prescription (P < .01) and a concomitant decrease in vitamin K antagonist prescription (P < .01). Despite this, the overall rate of anticoagulation remains below what would be predicted with perfect guideline compliance (75% vs 94%, P < .01). CONCLUSION: There has been a dramatic shift in clinical practice for AF patients requiring PCI, with increases in prescription of OAC even in the context of an increase in the use of DES. However, room for further practice optimization still exists
Flight test evaluation of predicted light aircraft drag, performance, and stability
A technique was developed which permits simultaneous extraction of complete lift, drag, and thrust power curves from time histories of a single aircraft maneuver such as a pull up (from V max to V stall) and pushover (to V max for level flight). The technique, which is an extension of nonlinear equations of motion of the parameter identification methods of Iliff and Taylor and includes provisions for internal data compatibility improvement as well, was shown to be capable of correcting random errors in the most sensitive data channel and yielding highly accurate results. Flow charts, listings, sample inputs and outputs for the relevant routines are provided as appendices. This technique was applied to flight data taken on the ATLIT aircraft. Lack of adequate knowledge of the correct full throttle thrust horsepower true airspeed variation and considerable internal data inconsistency made it impossible to apply the trajectory matching features of the technique
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