Assessment of team training in management of adverse acute events occurring during cardiopulmonary bypass procedure: a pilot study based on an animal simulation model (Fouilloux, Team training in cardiac surgery)

Successful cardiac surgery is highly dependent upon effective and efficient teamwork. Practical training and development will further enhance the team ability to react to a series of low-frequency occurring adverse events during cardiopulmonary bypass (CPB). One of our specialized educational programs focuses on training the whole team. This training is based on an original animal simulation model. The objective of this pilot study was to assess our method of training and learning in an attempt to optimize and improve team management and functioning. Methods: Four members of the same cardiac surgery team joined our program. They performed a common procedure, with a cardiopulmonary bypass (CPB) circuit set up to produce several adverse incidents. Events management was ana¬lyzed and debriefed in technical and non-technical perspectives. Results: Management of the adverse events was significantly improved. Discussion and debriefing time was fundamental in identifying the most appropriate management for each event. Rescue procedures were assimilated and team training was found to be effective, with the time reduced by up to 50% for 3 events and by up to 70% for air embolism. Conclusion: Our pilot program is an innovative, low-cost tool for the improvement of the management of adverse events occurring during CPB. It includes the different components of surgical education and training. Such an educational tool might be relevant for training. To confirm those encouraging results, it should be assessed in a larger surgical team panel. Further investigations are required for assessing efficiency in real conditions

Analysis of a 5-parent half diallel in dried pea (Pisum sativum L). I. Seed yield heterosis

Values of heterosis for seed yield and related traits have been calculated on F1 hybrids of dried pea (Pisum sativum L), obtained in a 5-parent half diallel cross. Lines used as parents represented a good sample of the genetic variability found in Northern Europe cultivars. The experiment was performed in microplots under competitive conditions (density: 100 pl/m2). Seed yield showed highly significant heterosis: 40% over the mid parent and 20% over the high parent respectively. Both general and specific combining ability were important. This study also concluded that heterosis was mainly expressed on branches. Heterosis for yield components was significant only for the number of pods/plant and the number of sseds/pod on the branches, but not for the number of seeds/pod on the whole plant or for dry weight/seed.Analyse d'un demi-diallèle à 5 parents chez le pois. I. Hétérosis du rendement en grains. Les valeurs d'hétérosis du rendement en grains et de caractères liés au rendement ont été calculées chez des hybrides F1 de pois (Pisum sativum L), obtenus dans un croisement demi-diallèle à 5 parents. Les lignées utilisées comme parents représentaient un bon échantillon de la variabilité génétique des cultivars du Nord de l'Europe. L'expérimentation a été effectuée en micro-parcelles, en conditions de compétition (densité : 100 pl/m2). Le rendement en grains a montré un hétérosis significatif : respectivement 40% par rapport au parent moyen et 20% par rapport au meilleur des 2 parents. Les aptitudes générale et spécifique à la combinaison étaient importantes. Cette étude a souligné le fait que le phénomène d'hétérosis s'exprimait principalement au niveau des ramifications. L'hétérosis pour les composantes du rendement était significatif seulement pour le nombre de gousses par plante et le nombre de graines par gousse sur les ramifications mais ne l'était pas pour le nombre de graines par gousse au niveau de la plante entière ni pour le poids sec du grain

Analysis of a 5-parent half diallel in dried pea (Pisum sativum L). I. Seed yield heterosis

Values of heterosis for seed yield and related traits have been calculated on F1 hybrids of dried pea (Pisum sativum L), obtained in a 5-parent half diallel cross. Lines used as parents represented a good sample of the genetic variability found in Northern Europe cultivars. The experiment was performed in microplots under competitive conditions (density: 100 pl/m2). Seed yield showed highly significant heterosis: 40% over the mid parent and 20% over the high parent respectively. Both general and specific combining ability were important. This study also concluded that heterosis was mainly expressed on branches. Heterosis for yield components was significant only for the number of pods/plant and the number of sseds/pod on the branches, but not for the number of seeds/pod on the whole plant or for dry weight/seed.Analyse d'un demi-diallèle à 5 parents chez le pois. I. Hétérosis du rendement en grains. Les valeurs d'hétérosis du rendement en grains et de caractères liés au rendement ont été calculées chez des hybrides F1 de pois (Pisum sativum L), obtenus dans un croisement demi-diallèle à 5 parents. Les lignées utilisées comme parents représentaient un bon échantillon de la variabilité génétique des cultivars du Nord de l'Europe. L'expérimentation a été effectuée en micro-parcelles, en conditions de compétition (densité : 100 pl/m2). Le rendement en grains a montré un hétérosis significatif : respectivement 40% par rapport au parent moyen et 20% par rapport au meilleur des 2 parents. Les aptitudes générale et spécifique à la combinaison étaient importantes. Cette étude a souligné le fait que le phénomène d'hétérosis s'exprimait principalement au niveau des ramifications. L'hétérosis pour les composantes du rendement était significatif seulement pour le nombre de gousses par plante et le nombre de graines par gousse sur les ramifications mais ne l'était pas pour le nombre de graines par gousse au niveau de la plante entière ni pour le poids sec du grain

Development of sequence-tagged-site (STS) PCR markers and study of simple-sequence-repeats (SSR) for variety testing in oilseed rape (Brassica Napus).

International audienc

Detection of pulmonary and coronary artery anomalies in tetralogy of ă Fallot using non-ECG-gated CT angiography

International audienceObjectives: To evaluate the use of non-ECG-gated computed tomography ă (CT) angiography to describe pulmonary and coronary defects in patients ă with tetralogy of Fallot (TOF). ă Patients and methods: This retrospective study was carried out on TOF ă patients having undergone pre-operative non-ECG-gated CT angiography ă between February 2007 and September 2012. The following clinical ă parameters were recorded: mean age at CT angiography, sex, the existence ă of genetic disease and the need to sedate the patient prior to CT ă angiography. CT data were analyzed retrospectively to determine the ă site(s) of pulmonary stenosis (infundibular, valvular or arterial), the ă size of pulmonary arteries and the presence of anomalous coronary artery ă courses. CT findings were then compared to the anatomy observed during ă surgery. ă Results: Thirty-five patients were included in the study. The mean age ă was 4.30 +/- 1.91 months (boys/girls = 17/18). Two patients had ă associated chromosome disorders (one 22q11 microdeletion and one CHARGE ă syndrome). Sixteen patients (45.71%) were sedated prior to CT. ă Pulmonary artery assessment revealed 24 patients (68.57%) with ă infundibular stenosis, 5 (17.5%) with infundibular and/or valvular ă stenosis, and 6 (21%) with anomalous pulmonary arteries. CT angiography ă also evidenced anomalous coronary arteries in 8 patients (22.85%). ă Conclusion: Due to its reduced scanning time and high spatial ă resolution, non-ECG-gated CT angiography is a non-invasive imaging ă modality that provides accurate information on pulmonary and coronary ă artery anatomy in patients with TOF. (C) 2016 Editions francaises de ă radiologie. Published by Elsevier Masson SAS. All rights reserved

An Outbreak of Kingella kingae Infections Complicating a Severe Hand, Foot, And Mouth Disease Outbreak in Nice, France, 2016.

International audienceWe report the investigative methods for the diagnosis of an epidemic and culture-negative K. kingae endocarditis complicating a severe outbreak of hand,foot, and mouth disease in a childcare center. The diagnosis was confirmed by PCR testings performed from cardiac tissue. Our findings argue for the systematic investigation of K. kingae outbreaks by using molecular tools in such context