326 research outputs found

    Some effects of ultraviolet light on mouse skin

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    Interviews On Main

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    Interviews On Main is the script of a one woman performance piece. It was conceived as an exploration and process of how to develop and write a working script, and later, see the piece come to fruition by producing, acting, and directing it. This solo show process has allowed me to delve into discovering my personal aesthetic in order to make a strong, individual artistic statement. Additionally, this process has helped me to learn how to be a solo creative artist, and to have cultivated individual material to perform when I am not cast professionally. This thesis includes a table of contents detailing the order of the parts. Firstly, this thesis contains a practical documentation of the artistic process; the description of early ideas, research and development of Interviews On Main, the editing process, and the final working script. It also includes a chapter of script and performance analysis, as well as a vision for possible expansion to a longer piece, and how to revive it. Finally, the thesis includes the sources consulted, or pertaining to, the process of development

    Whatever You Want Me to Be: The Purse, Identity, and Exchange in Ancient Greece

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    Since the 1930ā€™s, scholars have interpreted the motif of the coin purse in Greek pottery imagery in a variety of ways, often treating the exact same image to vastly different iconographic readings to effectively define the purse in the world of ā€˜genreā€™ images. Not only do many of these studies often neglect chronology or distribution, they also confine themselves to a set, often repeated handful of purse-images without considering the massive scale and repetition found in Greek vase-production. This study will utilize evidence that includes provenance, shape, and chronology, in addition to analyzing patterns of gestures and gendered interactions within a large number of purse scenes. This study will examine the ā€œpurseā€ as an iconographic element within Greek pottery through the construction of a catalogue of images built from the Beazley Archive 2 Pottery Database. It is through this analysis that the image of the purse, within the data provided, does not confine itself to a singular, definite reading, but is instead a nuanced motif containing many different potential meanings. Thus, due to the ambiguity of the purse motif, a multivalent approach is necessary when interpreting the potential meaning(s) of the purse for an ancient viewer

    Philosophy Forum

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    Selenoproteinsā€”Tracing the Role of a Trace Element in Protein Function

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    Selenium is an important component of several enzymes, replacing sulfur in cysteine residues. Its discovery and significance are described in this primer

    Recent trends in soft-tissue infection imaging.

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    This article discusses the current techniques and future directions of infection imaging with particular attention to respiratory, central nervous system, abdominal, and postoperative infections. The agents currently in use localize to areas of infection and inflammation. An infection-specific imaging agent would greatly improve the utility of scintigraphy in imaging occult infections. The superior spatial resolution of (18)F-fluorodeoxyglucose positron emission tomography ((18)F-FDG-PET) and its lack of reliance on a functional immune system, gives this agent certain advantages over the other radiopharmaceuticals. In respiratory tract infection imaging, an important advancement would be the ability to quantitatively delineate lung inflammation, allowing one to monitor the therapeutic response in a variety of conditions. Current studies suggest PET should be considered the most accurate quantitative method. Scintigraphy has much to offer in localizing abdominal infection as well as inflammation. We may begin to see a gradual increase in the usage of (18)F-FDG-PET in detecting occult abdominal infections. Commonly used modalities for imaging inflammatory bowel disease are scintigraphy with (111)In-oxine/(99m)Tc-HMPAO labeled autologous white blood cells. The literature on central nervous system infection imaging is relatively scarce. Few clinical studies have been performed and numerous new agents have been developed for this use with varying results. Further studies are needed to more clearly delineate the future direction of this field. In evaluating the postoperative spine, (99m)Tc-ciprofloxacin single-photon emission computed tomography (SPECT) was reported to be \u3e80% sensitive in patients more than 6 months after surgery. FDG-PET has also been suggested for this purpose and may play a larger role than originally thought. It appears PET/computed tomography (CT) is gaining support, especially in imaging those with fever of unknown origin or nonfunctional immune systems. Although an infection-specific agent is lacking, the development of one would greatly advance our ability to detect, localize, and quantify infections. Overall, imaging such an agent via SPECT/CT or PET/CT will pave the way for greater clinical reliability in the localization of infection

    Randomized, double-blind, placebo-controled clinical trial of sublingual immunotherapy in natural rubber latex allergic patients

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    <p>Abstract</p> <p>Background</p> <p>Natural rubber latex allergy is a common and unsolved health problem. Since the avoidance of exposure is very difficult, immunotherapy is strongly recommended, but before its use in patients, it is essential to prove the efficacy and safety of extracts.</p> <p>The aim of the present randomised, double-blind, placebo-controlled clinical trial was to assess the efficacy and tolerability of latex sublingual immunotherapy in adult patients undergoing permanent latex avoidance.</p> <p>Methods</p> <p>Twenty-eight adult latex-allergic patients (5 males and 23 females), with mean age of 39 years (range 24-57) were randomized to receive a commercial latex-sublingual immunotherapy or placebo during one year, followed by another year of open, active therapy. The following outcomes were measured at baseline and at the end of first and second year of follow-up: skin prick test, gloves-use score, conjunctival challenge test, total and specific IgE, basophil activation test, and adverse reactions monitoring.</p> <p>Results</p> <p>No significant difference in any of the efficacy <it>in vivo </it>variables was observed between active and placebo groups at the end of the placebo-controlled phase, nor when each group was compared with their baseline values at the end of the two year-study. An improvement in the average percentage of basophils activated was observed. During the induction phase, 4 reactions in the active group and 5 in the placebo group were recorded. During the maintenance phase, two patients dropped out due to pruritus and to acute dermatitis respectively.</p> <p>Conclusion</p> <p>Further studies are needed to evaluate latex-sublingual immunotherapy, since efficacy could not be demonstrated in adult patients with avoidance of the allergen.</p> <p>Trial registration number</p> <p><a href="http://www.anzctr.org.au/ACTRN12611000543987.aspx">ACTRN12611000543987</a></p
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