57 research outputs found

    A GEOSITE TO BE SAVED: THE TYRRHENIAN FOSSIL DEPOSIT ON THE ISLAND OF USTICA

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    During the 1960s, fossil beds characterized by a tropical-sea malacofauna were discovered by G. Ruggieri and G. Buccheri in the Island of Ustica, on the southern slope of Falconiera hill, 32 m asl. Thanks to the presence of Strombus bubonius and other Senegalese guests, the authors estimated that the molluscan fauna had lived around 125,000 years ago, during the Tyrrhenian stage. Recently on the initiative of the “Centro Studi e Documentazione Isola di Ustica”, a research has been initiated to verify the persistence of sand-layers mixed up with Tyrrhenian fossils, even though, in the last 50 years, that area has undergone great changes, because of earthworks which have sealed the deposit. The new research led to the discovery of a fossil assemblage formed by 22 taxa (16 species of gastropods and 6 of bivalves), characterized by the presence of some Senegalese guests and other accompanying species that can be associated with the Eutyrrhenian subunit (MIS 5.5). This is the main subject of this note, along with the suggestion to preserve what remains of the Ustica Tyrrhenian deposit

    Identification of 22 susceptibility loci associated with testicular germ cell tumors

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    Testicular germ cell tumors (TGCT) are the most common tumor in young white men and have a high heritability. In this study, the international Testicular Cancer Consortium assemble 10,156 and 179,683 men with and without TGCT, respectively, for a genome-wide association study. This meta-analysis identifies 22 TGCT susceptibility loci, bringing the total to 78, which account for 44% of disease heritability. Men with a polygenic risk score (PRS) in the 95th percentile have a 6.8-fold increased risk of TGCT compared to men with median scores. Among men with independent TGCT risk factors such as cryptorchidism, the PRS may guide screening decisions with the goal of reducing treatment-related complications causing long-term morbidity in survivors. These findings emphasize the interconnected nature of two known pathways that promote TGCT susceptibility: male germ cell development within its somatic niche and regulation of chromosomal division and structure, and implicate an additional biological pathway, mRNA translation

    Ha chiuso i battenti l'acceleratore Lep

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    "Tutto e' nato dall'antimateria"

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    LEP, prosegue la caccia alla particella

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