2,726 research outputs found
THE EFFECT OF IMPACT CONDITION ON THE RELATIONSHIP BETWEEN LINEAR AND ANGULAR ACCELERATION LINEAR
Helmets are mandatory in many contact sports and are designed to prevent traumatic brain injuries. When assessing their performance, angular acceleration is not measured, as it is generally assumed to be highly correlated with linear acceleration (Pellman et al., 2003). Although being common, this assumption is not supported by strong data. The aim of this study was to establish the relationship between linear and angular acceleration
THE DETERMINATION OF NOVEL IMPACT CONDITIONS FOR THE ASSESMENT OF LINEAR AND ANGULAR HEADFORM ACCELERATIONS
Sports helmets, albeit very effective at preventing traumatic brain injury, have not mitigated the risk of mild traumatic brain injury in sport (Flik, Lyman, & Marx, 2005). Current protocols utilized in sports helmet testing incorporate only impact vectors through the center of mass, eliciting primarily linear accelerations. Angular acceleration has been suggested to be a better predictor of diffuse head injury than linear acceleration (Holbourn, 1943); therefore, the objective of this study was to develop a protocol capable of producing and measuring both forms of acceleration for future implementation into sports helmet standards
PERCEIVED DIFFERENCES IN SKATING CHARACTERISTICS RESULTING FROM THREE CROSS SECTIONAL SKATE BLADE PROFILES
The purpose of this study was to document differences in perceived skating characteristics resulting from three unique cross sectional skate blade profiles. Sixteen (n=16) University level hockey players were used in this double blind study looking at the perceived performance differences of four different skate blade profiles. No significant differences were found between skate blade profiles, preferred skate blade profile and time to complete given drills. Future research should look at different blade profiles and their interaction at ice level
FTIR spectroscopic imaging and mapping with correcting lenses for studies of biological cells and tissues
Histopathology of tissue samples is used to determine the progression of cancer usually by staining and visual analysis. It is recognised that disease progression from healthy tissue to cancerous is accompanied by spectral signature changes in the mid-infrared range. In this work, FTIR spectroscopic imaging in transmission mode using a focal plane array (96 × 96 pixels) has been applied to the characterisation of Barrett's oesophageal adenocarcinoma. To correct optical aberrations, infrared transparent lenses were used of the same material (CaF2) as the slide on which biopsies were fixed. The lenses acted as an immersion objective, reducing scattering and improving spatial resolution. A novel mapping approach using a sliding lens is presented where spectral images obtained with added lenses are stitched together such that the dataset contained a representative section of the oesophageal tissue. Images were also acquired in transmission mode using high-magnification optics for enhanced spatial resolution, as well as with a germanium micro-ATR objective. The reduction of scattering was assessed using k-means clustering. The same tissue section map, which contained a region of high grade dysplasia, was analysed using hierarchical clustering analysis. A reduction of the trough at 1077 cm−1 in the second derivative spectra was identified as an indicator of high grade dysplasia. In addition, the spatial resolution obtained with the lens using high-magnification optics was assessed by measurements of a sharp interface of polymer laminate, which was also compared with that achieved with micro ATR-FTIR imaging. In transmission mode using the lens, it was determined to be 8.5 μm and using micro-ATR imaging, the resolution was 3 μm for the band at a wavelength of ca. 3 μm. The spatial resolution was also assessed with and without the added lens, in normal and high-magnification modes using a USAF target. Spectroscopic images of cells in transmission mode using two lenses are also presented, which are necessary for correcting chromatic aberration and refraction in both the condenser and objective. The use of lenses is shown to be necessary for obtaining high-quality spectroscopic images of cells in transmission mode and proves the applicability of the pseudo hemisphere approach for this and other microfluidic systems
Brexit: Modes of Uncertainty and Futures in an Impasse
Alongside the emergence of various populisms, Brexit and other contemporary geopolitical events have been presented as symptomatic of a generalizing and intensifying sense of uncertainty in the midst of a crisis of (neo)liberalism. In this paper we describe what kind of event Brexit is becoming in the impasse between the UK’s EU referendum in 2016 and its anticipated exit from the EU in 2019. Based on 108 interviews with people in the North‐East of England, we trace how Brexit is variously enacted and felt as an end, advent, a harbinger of worse to come, non‐event, disaster, and betrayed promise. By following how these incommensurate versions of Brexit take form and co‐exist we supplement explanatory and predictive approaches to the geographies of Brexit and exemplify an approach that traces what such geopolitical events become. Specifically, we use the concept of ‘modes of uncertainty’ as a way of discerning patterns in how present uncertainties are lived. A ‘mode of uncertainty’ is a shared set of practices animated by a distinctive mood through which futures are made present and felt. Rather than treat uncertainty as a static, explanatory context, we thus follow how different versions of Brexit are constituted through specific ‘modes of (un)certainty’ – negative hope, national optimisms, apprehensive hopefulness and fantasies of action ‐ that differentiate within a seemingly singular, shared sense of uncertainty
Reflection of light and heavy holes from a linear potential barrier
In this paper we study reflection of holes in direct-band semiconductors from
the linear potential barrier. It is shown that light-heavy hole transformation
matrix is universal. It depends only on a dimensionless product of the light
hole longitudinal momentum and the characteristic length determined by the
slope of the potential and doesn't depend on the ratio of light and heavy hole
masses, provided this ratio is small. It is shown that the transformation
coefficient goes to zero both in the limit of small and large longitudinal
momenta, however the phase of a reflected hole is different in these limits. An
approximate analytical expression for the light-heavy hole transformation
coefficient is found.Comment: 6 pages, 2 figure
Quadratic response theory for spin-orbit coupling in semiconductor heterostructures
This paper examines the properties of the self-energy operator in
lattice-matched semiconductor heterostructures, focusing on nonanalytic
behavior at small values of the crystal momentum, which gives rise to
long-range Coulomb potentials. A nonlinear response theory is developed for
nonlocal spin-dependent perturbing potentials. The ionic pseudopotential of the
heterostructure is treated as a perturbation of a bulk reference crystal, and
the self-energy is derived to second order in the perturbation. If spin-orbit
coupling is neglected outside the atomic cores, the problem can be analyzed as
if the perturbation were a local spin scalar, since the nonlocal spin-dependent
part of the pseudopotential merely renormalizes the results obtained from a
local perturbation. The spin-dependent terms in the self-energy therefore fall
into two classes: short-range potentials that are analytic in momentum space,
and long-range nonanalytic terms that arise from the screened Coulomb potential
multiplied by a spin-dependent vertex function. For an insulator at zero
temperature, it is shown that the electronic charge induced by a given
perturbation is exactly linearly proportional to the charge of the perturbing
potential. These results are used in a subsequent paper to develop a
first-principles effective-mass theory with generalized Rashba spin-orbit
coupling.Comment: 20 pages, no figures, RevTeX4; v2: final published versio
High intensity exercise decreases IP6K1 muscle content & improves insulin sensitivity in glucose intolerant individuals
Context
Insulin resistance in skeletal muscle contributes to whole body hyperglycaemia and the secondary complications associated with type 2 diabetes. Inositol hexakisphosphate kinase-1 (IP6K1) may inhibit insulin-stimulated glucose transport in this tissue type.
Objective
Muscle and plasma IP6K1 were correlated with two-compartment models of glucose control in insulin-resistant hyperinsulimic individuals. Muscle IP6K1 was also compared following two different exercise trials.
Methods
Nine pre-diabetic [HbA1c; 6.1 (0.2) %)] were recruited to take part in a resting control, a continuous exercise (90% of lactate threshold) and a high-intensity exercise trial (6 x 30 sec sprints). Muscle biopsies were drawn pre- and post each 60-minute trial. A labeled ([6,62H2]glucose) intravenous glucose tolerance test (IVGTT) was performed immediately after the second muscle sample.
Results
Fasting muscle IP6K1 content did not correlate with SI2* (P = 0.961). High-intensity exercise reduced IP6K1 muscle protein and mRNA expression (P = 0.001). There was no effect on protein IP6K1 content following continuous exercise. Akt308 phosphorylation of was significantly greater following high-intensity exercise. Intermittent exercise reduced hepatic glucose production (HGP) following the same trial. The same intervention also improved SI2* and this was significantly greater compared to the continuous exercise improvements. Our in vitro experiment demonstrated that the chemical inhibition of IP6K1 increased insulin signaling in C2C12 myotubes.
Conclusions
The in vivo and in vitro approaches used in the current study suggest that a decrease in muscle IP6K1 may be linked to whole body improvements in SI2*. In addition, high-intensity exercise reduces HPG in insulin-resistant individuals
First-principles envelope-function theory for lattice-matched semiconductor heterostructures
In this paper a multi-band envelope-function Hamiltonian for lattice-matched
semiconductor heterostructures is derived from first-principles norm-conserving
pseudopotentials. The theory is applicable to isovalent or heterovalent
heterostructures with macroscopically neutral interfaces and no spontaneous
bulk polarization. The key assumption -- proved in earlier numerical studies --
is that the heterostructure can be treated as a weak perturbation with respect
to some periodic reference crystal, with the nonlinear response small in
comparison to the linear response. Quadratic response theory is then used in
conjunction with k.p perturbation theory to develop a multi-band effective-mass
Hamiltonian (for slowly varying envelope functions) in which all interface
band-mixing effects are determined by the linear response. To within terms of
the same order as the position dependence of the effective mass, the quadratic
response contributes only a bulk band offset term and an interface dipole term,
both of which are diagonal in the effective-mass Hamiltonian. Long-range
multipole Coulomb fields arise in quantum wires or dots, but have no
qualitative effect in two-dimensional systems beyond a dipole contribution to
the band offsets.Comment: 25 pages, no figures, RevTeX4; v3: final published versio
Lattice Resistance and Peierls Stress in Finite-size Atomistic Dislocation Simulations
Atomistic computations of the Peierls stress in fcc metals are relatively
scarce. By way of contrast, there are many more atomistic computations for bcc
metals, as well as mixed discrete-continuum computations of the Peierls-Nabarro
type for fcc metals. One of the reasons for this is the low Peierls stresses in
fcc metals. Because atomistic computations of the Peierls stress take place in
finite simulation cells, image forces caused by boundaries must either be
relaxed or corrected for if system size independent results are to be obtained.
One of the approaches that has been developed for treating such boundary forces
is by computing them directly and subsequently subtracting their effects, as
developed by V. B. Shenoy and R. Phillips [Phil. Mag. A, 76 (1997) 367]. That
work was primarily analytic, and limited to screw dislocations and special
symmetric geometries. We extend that work to edge and mixed dislocations, and
to arbitrary two-dimensional geometries, through a numerical finite element
computation. We also describe a method for estimating the boundary forces
directly on the basis of atomistic calculations. We apply these methods to the
numerical measurement of the Peierls stress and lattice resistance curves for a
model aluminum (fcc) system using an embedded-atom potential.Comment: LaTeX 47 pages including 20 figure
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