Blaming the sinner or the sin? : just world beliefs, religiosity, and explanations for suffering

Within the literature on just world beliefs there is a recurring argument that religiosity is positively related to just world beliefs. This thesis, along with other studies, indicates otherwise. Measures of religiosity and general religious beliefs were not substantively related to the belief in a just world in two surveys of university undergraduates. Unsatisfactory accounts of the relationship between religiosity and just world beliefs obscure some previously unexamined assumptions about this relationship. This thesis has examined the assumption that the Christian religion promotes the belief in a just world, revealing that religious beliefs about suffering challenge the belief in the justness of the world. Highly religious Christians indicated negligible support for the belief that people who are suffering are being punished by God. The dominant explanations for human suffe1ing were that suffering is a result of the fallen state of humankind and the consequence of the actions of sinful people. Religious beliefs about suffering were argued, and found in some instances, to be important in determining the nature of the relationship between religiosity and just world beliefs. The research presented here provides a more accurate description of the nature of the relationship between the belief in a just universe and the belief in a just world. There has been a tendency to overstate the case for a positive relationship between just world beliefs and religiosity, based on the explanation that religious people believe in ultimate justice. The thesis found that just world beliefs and just universe beliefs are distinct and possibly independent beliefs. Believing that the universe is just is not likely to be highly related to the belief in justice on earth. In contrast to just world beliefs, religiosity was found to be strongly related to the belief in the justness of the universe

Iron Uptake And Accumulation Is A Target Of Nickel Toxicity During The Lag Phase In Escherichia Coli

Various transition metals are essential to all forms of life, and are only required in trace amounts. But this dependence comes as a double-edged sword. All organisms must maintain a careful intracellular quota that does not traverse outside an acceptable range. One transition metal in particular is nickel. The importance of this transition metal has been debated widely and its function varies greatly between organisms, including bacteria. However, the adverse effects caused by over exposure to this metal have been the center of much experimentation in recent years. Still, the mechanisms of nickel toxicity and the subsequent effects on cellular health, particularly the stability of the iron metallome, in bacteria remains poorly understood. The overall aim of these studies was to further elucidate the effects of nickel toxicity on the overall state of iron homeostasis during the lag phase of growth, using Escherichia coli as the model organism. We therefore developed a growth scheme that forced cells pre-adapted to growth on glucose to alter their central carbon metabolism to accommodate growth on gluconate. This shift allotted an additional stress on the iron metallome, given that the 6-phosphogluconate dehydratase enzyme vital to gluconate metabolism requires a [4Fe-4S] cluster for proper function. Our data demonstrated that the activity of this enzyme is absent in the presence of nickel, and thereby inhibited growth on gluconate during nickel exposure. ICP-MS and EPR analyses further confirmed nickel exposure during the lag phase inhibited iron uptake, and several genes central to iron uptake and Fe-S cluster synthesis were expressed through the lag phase. Finally, wild type cells were observed to ultimately adapt to the nickel stress and grow to stationary phase. It was determined that these nickel treated cells developed a new phenotype that was resistant to nickel toxicity. The ferric reductase YqjH was linked to the development of this nickel resistance. A nickelhypersensitive DyqjH mutant, however, did not develop resistance to nickel toxicity as the wild type strain had done. Finally, YqjH has been linked to both iron and nickel homeostasis, suggesting a possible role for YqjH during nickel stress

The California Planet Survey IV: A Planet Orbiting the Giant Star HD 145934 and Updates to Seven Systems with Long-Period Planets

We present an update to seven stars with long-period planets or planetary candidates using new and archival radial velocities from Keck-HIRES and literature velocities from other telescopes. Our updated analysis better constrains orbital parameters for these planets, four of which are known multi-planet systems. HD 24040 b and HD 183263 c are super-Jupiters with circular orbits and periods longer than 8 yr. We present a previously unseen linear trend in the residuals of HD 66428 indicative on an additional planetary companion. We confirm that GJ 849 is a multi-planet system and find a good orbital solution for the c component: it is a $1 M_{\rm Jup}$ planet in a 15 yr orbit (the longest known for a planet orbiting an M dwarf). We update the HD 74156 double-planet system. We also announce the detection of HD 145934 b, a $2 M_{\rm Jup}$ planet in a 7.5 yr orbit around a giant star. Two of our stars, HD 187123 and HD 217107, at present host the only known examples of systems comprising a hot Jupiter and a planet with a well constrained period $> 5$ yr, and with no evidence of giant planets in between. Our enlargement and improvement of long-period planet parameters will aid future analysis of origins, diversity, and evolution of planetary systems.Comment: 16 pages, 13 figures. Accepted for publication in Ap

Retired A Stars and Their Companions VI. A Pair of Interacting Exoplanet Pairs Around the Subgiants 24 Sextanis and HD200964

We report radial velocity measurements of the G-type subgiants 24 Sextanis (=HD90043) and HD200964. Both are massive, evolved stars that exhibit periodic variations due to the presence of a pair of Jovian planets. Photometric monitoring with the T12 0.80m APT at Fairborn Observatory demonstrates both stars to be constant in brightness to <= 0.002 mag, thus strengthening the planetary interpretation of the radial velocity variations. 24 Sex b,c have orbital periods of 453.8 days and 883~days, corresponding to semimajor axes 1.333 AU and 2.08 AU, and minimum masses (Msini) 1.99 Mjup and 0.86 Mjup, assuming a stellar mass 1.54 Msun. HD200964 b,c have orbital periods of 613.8 days and 825 days, corresponding to semimajor axes 1.601 AU and 1.95 AU, and minimum masses 1.85 Mjup and 0.90 Mjup, assuming M* = 1.44 Msun. We also carry out dynamical simulations to properly account for gravitational interactions between the planets. Most, if not all, of the dynamically stable solutions include crossing orbits, suggesting that each system is locked in a mean motion resonance that prevents close encounters and provides long-term stability. The planets in the 24 Sex system likely have a period ratio near 2:1, while the HD200964 system is even more tightly packed with a period ratio close to 4:3. However, we caution that further radial velocity observations and more detailed dynamical modelling will be required to provide definitive and unique orbital solutions for both cases, and to determine whether the two systems are truly resonant.Comment: AJ accepte

Nickel Exposure Reduces Enterobactin Production in Escherichia Coli

Escherichia coli is a well- studied bacterium that can be found in many niches, such as industrial wastewater, where the concentration of nickel can rise to low- millimolar levels. Recent studies show that nickel exposure can repress pyochelin or induce pyo-verdine siderophore production in Pseudomonas aueroginosa. Understanding the mo-lecular cross- talk between siderophore production, metal homeostasis, and metal toxicity in microorganisms is critical for designing bioremediation strategies for metal- contaminated sites. Here, we show that high- nickel exposure prolongs lag phase duration as a result of low- intracellular iron levels in E. coli. Although E. coli cells respond to low- intracellular iron during nickel stress by maintaining high expres-sion of iron uptake systems such as fepA, the demand for iron is not met due to a lack of siderophores in the extracellular medium during nickel stress. Taken together, these results indicate that nickel inhibits iron accumulation in E. coli by reducing the presence of enterobactin in the extracellular medium

Five planets and an independent confirmation of HD 196885Ab from Lick Observatory

We present time series Doppler data from Lick Observatory that reveal the presence of long-period planetary companions orbiting nearby stars. The typical eccentricity of these massive planets are greater than the mean eccentricity of known exoplanets. HD30562b has Msini = 1.29 Mjup, with semi-major axis of 2.3 AU and eccentricity 0.76. The host star has a spectral type F8V and is metal rich. HD86264b has Msini = 7.0 Mjup, arel = 2.86 AU, an eccentricity, e = 0.7 and orbits a metal-rich, F7V star. HD87883b has Msini = 1.78 Mjup, arel = 3.6 AU, e = 0.53 and orbits a metal-rich K0V star. HD89307b has Msini = 1.78 Mjup, arel = 3.3 AU, e = 0.24 and orbits a G0V star with slightly subsolar metallicity. HD148427b has Msini = 0.96 Mjup, arel = 0.93 AU, eccentricity of 0.16 and orbits a metal rich K0 subgiant. We also present velocities for a planet orbiting the F8V metal-rich binary star, HD196885A. The planet has Msini = 2.58 Mjup, arel = 2.37 AU, and orbital eccentricity of 0.48, in agreement with the independent discovery by Correia et al. 2008.Comment: 12 figures, 8 tables, accepted Ap

A first-in-human, randomized, controlled, subject- and reviewer-blinded multicenter study of Actamax™ Adhesion Barrier

Purpose: Post-surgical adhesions remain a significant concern following abdominopelvic surgery. This study was to assess safety, manageability and explore preliminary efficacy of applying a degradable hydrogel adhesion barrier to areas of surgical trauma following gynecologic laparoscopic abdominopelvic surgery. Methods: This first-in-human, prospective, randomized, multicenter, subject- and reviewer-blinded clinical study was conducted in 78 premenopausal women (18–46 years) wishing to maintain fertility and undergoing gynecologic laparoscopic abdominopelvic surgery with planned clinically indicated second-look laparoscopy (SLL) at 4–12 weeks. The first two patients of each surgeon received hydrogel, up to 30 mL sprayed over all sites of surgical trauma, and were assessed for safety and application only (n = 12). Subsequent subjects (n = 66) were randomized 1:1 to receive either hydrogel (Treatment, n = 35) or not (Control, n = 31); 63 completed the SLL. Results: No adverse event was assessed as serious, or possibly device related. None was severe or fatal. Adverse events were reported for 17 treated subjects (17/47, 36.2%) and 13 Controls (13/31, 41.9%). For 95.7% of treated subjects, surgeons found the device “easy” or “very easy” to use; in 54.5%, some residual material was evident at SLL. For 63 randomized subjects who completed the SLL, adjusted between-group difference in the change from baseline adhesion score demonstrated a 41.4% reduction for Treatment compared with Controls (p = 0.017), with a 49.5% reduction (p = 0.008) among myomectomy subjects (n = 34). Conclusion: Spray application of a degradable hydrogel adhesion barrier during gynecologic laparoscopic abdominopelvic surgery was performed easily and safely, without evidence of clinically significant adverse outcomes. Data suggest the hydrogel was effective in reducing postoperative adhesion development, particularly following myomectomy