20 research outputs found
Reversal of Graft-Versus-Host Disease with Infusion of Stored Autologous Bone Marrow Cells Following Combined Liver-Bone Marrow Allotransplantation in Man.
Ăndice SPAD e produção de batata, em duas Ă©pocas de plantio, em função de doses de nitrogĂȘnio
Regulated Nuclear Trafficking of rpL10A Mediated by NIK1 Represents a Defense Strategy of Plant Cells against Virus
The NSP-interacting kinase (NIK) receptor-mediated defense pathway has been identified recently as a virulence target of the geminivirus nuclear shuttle protein (NSP). However, the NIK1âNSP interaction does not fit into the elicitorâreceptor model of resistance, and hence the molecular mechanism that links this antiviral response to receptor activation remains obscure. Here, we identified a ribosomal protein, rpL10A, as a specific partner and substrate of NIK1 that functions as an immediate downstream effector of NIK1-mediated response. Phosphorylation of cytosolic rpL10A by NIK1 redirects the protein to the nucleus where it may act to modulate viral infection. While ectopic expression of normal NIK1 or a hyperactive NIK1 mutant promotes the accumulation of phosphorylated rpL10A within the nuclei, an inactive NIK1 mutant fails to redirect the protein to the nuclei of co-transfected cells. Likewise, a mutant rpL10A defective for NIK1 phosphorylation is not redirected to the nucleus. Furthermore, loss of rpL10A function enhances susceptibility to geminivirus infection, resembling the phenotype of nik1 null alleles. We also provide evidence that geminivirus infection directly interferes with NIK1-mediated nuclear relocalization of rpL10A as a counterdefensive measure. However, the NIK1-mediated defense signaling neither activates RNA silencing nor promotes a hypersensitive response but inhibits plant growth and development. Although the virulence function of the particular geminivirus NSP studied here overcomes this layer of defense in Arabidopsis, the NIK1-mediated signaling response may be involved in restricting the host range of other viruses
TAXAS DE RECUPERAĂĂO DE BORO POR EXTRATORES EM SOLOS DA BAHIA E DE MINAS GERAIS, NA PRESENĂA E AUSĂNCIA DE CALAGEM
Predicting site index from climate and soil variables for cork oak (Quercus suber L.) stands in Portugal
Site productivity, assessed through site index, was modelled using partial least
squares regression as a function of soil and climatic variables. Two alternative models were
developed: a full model, considering all available explanatory variables, and a reduced
model, considering only variables that can be obtained without digging a soil pit. The
reduced model was used for mapping the site index distribution in Portugal, on the basis of
existing digital cartography available for the whole country. The developed models indicate
the importance of water availability and soil water holding capacity for site index
value distribution. Site index was related to climate, namely evaporation and frost, and soil
characteristics such as lithology, soil texture, soil depth, thickness of the A horizon and soil
classification. The variability of the estimated values within the map (9.5â16.8 m with an
average value of 13.4 m) reflects the impact of soil characteristics on the site productivity
estimation. These variables should be taken into consideration during the establishment of
new plantations of cork oak, and management of existing plantations. Results confirm the
potential distribution of cork oak in coastal regions. They also suggest the existence of a
considerable area, located both North and South of the Tagus river, where site indices
values of medium (]13;15]) to high (]15;17]) productivity classes may be expected. The
species is then expected to be able to have good productivity along the northern coastal
areas of Portugal, where presently it is not a common species but where, according to
historical records, it occurred until the middle of the sixteenth century. The present
research focused on tree growth. Cork growth and cork quality distribution needs to be
further researched through the establishment of long term experimental sites along the distribution area of cork oak, namely in the central and northern coastal areas of the
countryinfo:eu-repo/semantics/publishedVersio