An equation of state from cool-dense fluids to hot gases for mixed elements

An equation of state for the domain extending from hot gases to cool-dense fluids is formulated for a hydrogen-helium mixture. The physical processes take account of temperature ionization and dissociation, electron degeneracy, Coulomb coupling and pressure ionization. Pressure ionization and Coulomb coupling are studied with simple and comprehensive modeling. A single and complete algorithm is achieved with explicit expressions available for the whole domain from hot gases to cool dense fluids ($T>10^2$). Pressure ionization and Coulomb coupling have been examined for their contributions to the pressure and internal energy. The result reveals that their contributions smooth the variation of the pressure and internal energy in the region of pressure ionization even at very low temperatures.Comment: 10 pages, 8 figures, ApJ, accepted, E-mail: [email protected]

Alfven node-free vibrations of white dwarf in the model of solid star with toroidal magnetic field

In the context of the white dwarf asteroseismology, we investigate vibrational properties of a non-convective solid star with an axisymmetric purely toroidal intrinsic magnetic field of two different shapes. Focus is laid on regime of node-free global Lorentz-force-driven vibrations about symmetry axis at which material displacements have one and the same form as those for nodeless spheroidal and torsional vibrations restored by Hooke's force of elastic shear stresses. Particular attention is given to the even-parity poloidal Alfven modes whose frequency spectra are computed in analytic form showing how the purely toroidal magnetic fields completely buried beneath the star surface can manifest itself in seismic vibrations of non-magnetic white dwarfs. The obtained spectral formulae are discussed in juxtaposition with those for Alfven modes in the solid star model with the poloidal, homogeneous internal and dipolar external, magnetic field whose inferences are relevant to Alfven vibrations in magnetic white dwarfs.Comment: Accepted for publication in Astrophysics & Space Scienc

Feasibility of identifying household contacts of rifampin-and multidrug-resistant tuberculosis cases at high risk of progression to tuberculosis disease

CITATION: Gupta, A. et al. 2020. Feasibility of identifying household contacts of rifampin-and multidrug-resistant tuberculosis cases at high risk of progression to tuberculosis disease. Clinical infectious diseases, 70(3): 425–435. doi:10.1093/cid/ciz235The original publication is available at https://academic.oup.com/cid/Background: We assessed multidrug-resistant tuberculosis (MDR-TB) cases and their household contacts (HHCs) to inform the development of an interventional clinical trial. Methods: We conducted a cross-sectional study of adult MDR-TB cases and their HHCs in 8 countries with high TB burdens. HHCs underwent symptom screenings, chest radiographies, sputum TB bacteriologies, TB infection (TBI) testing (tuberculin skin test [TST] and interferon gamma release assay [IGRA]), and human immunodeficiency virus (HIV) testing. Results: From October 2015 to April 2016, 1016 HHCs from 284 MDR-TB cases were enrolled. At diagnosis, 69% of MDR-TB cases were positive for acid-fast bacilli sputum smears and 43% had cavitary disease; at study entry, 35% remained smear positive after a median MDR-TB treatment duration of 8.8 weeks. There were 9 HHCs that were diagnosed with TB prior to entry and excluded. Of the remaining 1007 HHCs, 41% were male and the median age was 25 years. There were 121 (12%) HHCs that had new cases of TB identified: 17 (2%) were confirmed, 33 (3%) probable, and 71 (7%) possible TB cases. The TBI prevalence (defined as either TST or IGRA positivity) was 72% and varied by age, test used, and country. Of 1007 HHCs, 775 (77%) were considered high-risk per these mutually exclusive groups: 102 (10%) were aged <5 years; 63 (6%) were aged ≥5 and were infected with HIV; and 610 (61%) were aged ≥5 years, were negative for HIV or had an unknown HIV status, and were TBI positive. Only 21 (2%) HHCs were on preventive therapy. Conclusions: The majority of HHCs in these high-burden countries were at high risk of TB disease and infection, yet few were receiving routine preventive therapy. Trials of novel, preventive therapies are urgently needed to inform treatment policy and practice.https://academic.oup.com/cid/article/70/3/425/5426963?login=truePublishers versio