Wireless Biosensing Network for Drivers' Health Monitoring

Biosensors integrated into the vehicle controller area network are used for detecting symptoms such as anxiety, pain, and fatigue that may affect driving safety. The proposed system provides a flexible option for implementation in a diverse range of mass-produced automotive accessories without affecting the driver's movement

Effects of RANKL-Targeted Therapy in Immunity and Cancer.

The role of the receptor activator of nuclear factor-κB ligand (RANKL)/RANK system is well characterized within bone, where RANKL/RANK signaling mediates osteoclastogenesis and bone resorption. However, this system has also been shown to influence biologic processes beyond the skeletal system, including in the immune system and in cancer. RANKL/RANK signaling is important in lymph-node development, lymphocyte differentiation, dendritic cell survival, T-cell activation, and tolerance induction. The RANKL/RANK axis may also have direct, osteoclast-independent effects on tumor cells. Indeed, activity of the RANKL/RANK pathway in cancer cells has been correlated with tumor progression and advanced disease. Denosumab, a fully human monoclonal antibody against RANKL, inhibits osteoclastogenesis and is widely used not just for the treatment of osteoporosis, but for the prevention of skeletal-related events from bone metastases in solid malignancies such as breast and prostate cancer. The potential effects of denosumab on the immune system have been largely ignored. Nevertheless, with the emergence of immunotherapies for cancer, denosumab may impact the effectiveness of these therapies, especially if they are given in combination. In this article, we review the role of RANKL/RANK in bone, immunity, and cancer. Examining the potential effects of routine treatment with denosumab beyond the bone represents an important area of investigation

Fragmentation in DIS

The fragmentation properties in deep-inelastic scattering (DIS) at HERA are investigated in order to test perturbative QCD and quark fragmentation universality. Selected results for the inclusive single particle distributions and the angular two-particle correlations in the current region of the Breit frame are presented and compared to results from $e^{+}e^{-}$ collisions. The extension of the DIS fragmentation studies to the target region of the Breit frame are also reported.Comment: 3 pages, 4 figures, Proc. of the 7th Int. Workshop on Deep Inelastic Scattering and QCD (DIS99), Zeuthen, Germany, April 19-23, 1999, to appear in Nucl. Phys. B (Proc. Suppl.

China's One-Child Policy and the Empowerment of Urban Daughters

Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/65532/1/aa.2002.104.4.1098.pd

Theoretical studies of solar-pumped lasers

The power output of a black body solar-pumped laser as a function of time (computer graphic solutions) and under steady state conditions (analytic conditions); computer analyses of polymerization using lasers; and metallic sodium as a laser medium were studied