5,772 research outputs found

    Distinct forms of the ß subunit of GTP-binding regulatory proteins identified by molecular cloning

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    Two distinct β subunits of guanine nucleotide-binding regulatory proteins have been identified by cDNA cloning and are referred to as β 1 and β 2 subunits. The bovine transducin β subunit (β 1) has been cloned previously. We have now isolated and analyzed cDNA clones that encode the β 2 subunit from bovine adrenal, bovine brain, and a human myeloid leukemia cell line, HL-60. The 340-residue Mr 37,329 β 2 protein is 90% identical with β 1 in predicted amino acid sequence, and it is also organized as a series of repetitive homologous segments. The major mRNA that encodes the bovine β 2 subunit is 1.7 kilobases in length. It is expreβed at lower levels than β 1 subunit mRNA in all tiβues examined. The β 1 and β 2 meβages are expreβed in cloned human cell lines. Hybridization of cDNA probes to bovine DNA showed that β 1 and β 2 are encoded by separate genes. The amino acid sequences for the bovine and human β 2 subunit are identical, as are the amino acid sequences for the bovine and human β 1 subunit. This evolutionary conservation suggests that the two β subunits have different roles in the signal transduction process

    On graded polynomial identities with an antiautomorphism

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    AbstractLet G be a commutative monoid with cancellation and let R be a strongly G-graded associative algebra with finite G-grading and with antiautomorphism. Suppose that R satisfies a graded polynomial identity with antiautomorphism. We show that R is a PI algebra

    Characterization of carbon nanotubes synthesized from hydrocarbon-rich flame

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    The present study focuses on the characterization of carbon nanotubes (CNTs) synthesized from flame under an atmospheric condition. A laminar flame burner was utilized to establish a rich premixed propane/air flame at the equivalence ratio Φ = 1.8-2.2. The flame was impinged on a stainless steel wire mesh coated with nickel (Ni) catalyst to grow CNTs. Distribution and yield of the CNTs on the substrate were quantified. Carbon nanotubes formed on the substrate were harvested and characterized using scanning electron microscopy (SEM), field emission scanning electron microscopy (FESEM), energy dispersive X-ray spectroscopy (EDX), and thermogravimetric analysis (TGA). The FESEM micrograph showed that the CNTs produced were in disarray. The synthesized CNTs were an average of 50-60 nm in diameter while the length of the tubes was in the order of microns. TGA analysis showed that 75% of CNTs were present in the sample and the oxidation temperature was 510°C

    The bends on a quantum waveguide and cross-products of Bessel functions

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    A detailed analysis of the wave-mode structure in a bend and its incorporation into a stable algorithm for calculation of the scattering matrix of the bend is presented. The calculations are based on the modal approach. The stability and precision of the algorithm is numerically and analytically analysed. The algorithm enables precise numerical calculations of scattering across the bend. The reflection is a purely quantum phenomenon and is discussed in more detail over a larger energy interval. The behaviour of the reflection is explained partially by a one-dimensional scattering model and heuristic calculations of the scattering matrix for narrow bends. In the same spirit we explain the numerical results for the Wigner-Smith delay time in the bend.Comment: 34 pages, 21 figure

    Magnetic resonance peak and nonmagnetic impurities

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    Nonmagnetic Zn impurities are known to strongly suppress superconductivity. We review their effects on the spin excitation spectrum in YBa2Cu3O7\rm YBa_2Cu_3O_{7}, as investigated by inelastic neutron scattering measurements.Comment: Proceedings of Mato Advanced Research Workshop BLED 2000. To appear in Nato Science Series: B Physic

    Toxic metal concentrations in cigarettes obtained from U.S. smokers in 2009 : results from the International Tobacco Control (ITC) United States survey cohort

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    This research was funded by grants from the U.S. National Cancer Institute (R01 CA100362 and P01 CA138389), and the Canadian Institutes of Health Research (115016). Geoffrey T. Fong was supported by a Senior Investigator Award from the Ontario Institute for Cancer Research (OICR) and a Prevention Scientist Award from the Canadian Cancer Society Research Institute.Smoking-related diseases can be attributed to the inhalation of many different toxins, including heavy metals, which have a host of detrimental health effects. The current study reports the levels of arsenic (As), cadmium (Cd), chromium (Cr), nickel (Ni), and lead (Pb) in cigarettes obtained from adult smokers participating in the 2009 wave of the ITC United States Survey (N = 320). The mean As, Cd, Cr, Ni, and Pb levels were 0.17, 0.86, 2.35, 2.21, and 0.44 mu g/g, respectively. There were some differences in metal concentrations of cigarette brands produced by different manufacturers, suggesting differences in the source of tobaccos used by different companies. For Ni, there were significant pairwise differences between Philip Morris U.S. (PMUSA) and R.J. Reynolds (RJR) brands (PMUSA higher; p 0.10). Because of the variety of toxic heavy metals in cigarette tobacco, and their numerous negative health effects, metal content in cigarette tobacco should be reduced.Publisher PDFPeer reviewe

    Non-resonant leptogenesis in seesaw models with an almost conserved B-L

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    We review the motivations and some results on leptogenesis in seesaw models with an almost conserved lepton number. The paper is based on a talk given at the 5th International Symposium on Symmetries in Subatomic Physics, SSP2012.Comment: 8 pages, 1 figure. Published in the proceedings of the 5th International Symposium on Symmetries in Subatomic Physics, SSP201
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