329 research outputs found
Physics of Trans-Planckian Gravity
We study the field theoretical description of a generic theory of gravity
flowing to Einstein General Relativity in IR. We prove that, if ghost-free, in
the weakly coupled regime such a theory can never become weaker than General
Relativity. Using this fact, as a byproduct, we suggest that in a ghost-free
theory of gravity trans-Planckian propagating quantum degrees of freedom cannot
exist. The only physical meaning of a trans-Planckian pole is the one of a
classical state (Black Hole) which is described by the light IR quantum degrees
of freedom and gives exponentially-suppressed contributions to virtual
processes. In this picture Einstein gravity is UV self-complete, although not
Wilsonian, and sub-Planckian distances are unobservable in any healthy theory
of gravity. We then finally show that this UV/IR correspondence puts a severe
constraint on any attempt of conventional Wilsonian UV-completion of
trans-Planckian gravity. Specifically, there is no well-defined energy domain
in which gravity could become asymptotically weak or safe.Comment: 23 pages, 4 figures, v2: Paper reorganized to improve clarity;
additional explanations and references added; version accepted for
publication in Phys. Rev.
Itinerant ferromagnetism in half-metallic CoS_2
We have investigated electronic and magnetic properties of the pyrite-type
CoS_2 using the linearized muffin-tin orbital (LMTO) band method. We have
obtained the ferromagnetic ground state with nearly half-metallic nature. The
half-metallic stability is studied by using the fixed spin moment method. The
non-negligible orbital magnetic moment of Co 3d electrons is obtained as in the local spin density approximation (LSDA). The calculated
ratio of the orbital to spin angular momenta / = 0.15 is
consistent with experiment. The effect of the Coulomb correlation between Co 3d
electrons is also explored with the LSDA + U method. The Coulomb correlation at
Co sites is not so large, eV, and so CoS_2 is possibly
categorized as an itinerant ferromagnet. It is found that the observed
electronic and magnetic behaviors of CoS_2 can be described better by the LSDA
than by the LSDA + U.Comment: 4 pages, 3 postscript figure
Interactions of Ar(9+) and metastable Ar(8+) with a Si(100) surface at velocities near the image acceleration limit
Auger LMM spectra and preliminary model simulations of Ar(9+) and metastable
Ar(8+) ions interacting with a clean monocrystalline n-doped Si(100) surface
are presented. By varying the experimental parameters, several yet undiscovered
spectroscopic features have been observed providing valuable hints for the
development of an adequate interaction model. On our apparatus the ion beam
energy can be lowered to almost mere image charge attraction. High data
acquisition rates could still be maintained yielding an unprecedented
statistical quality of the Auger spectra.Comment: 34 pages, 11 figures, http://pikp28.uni-muenster.de/~ducree
Chlamydophila pneumoniae induces a sustained airway hyperresponsiveness and inflammation in mice
Background: It has been reported that Chlamydophila (C.) pneumoniae is involved in the initiation and promotion of asthma and chronic obstructive pulmonary diseases (COPD). Surprisingly, the effect of C. pneumoniae on airway function has never been investigated.Methods: In this study, mice were inoculated intranasally with C. pneumoniae (strain AR39) on day 0 and experiments were performed on day 2, 7, 14 and 21.Results: We found that from day 7, C. pneumoniae infection causes both a sustained airway hyperresponsiveness and an inflammation. Interferon-γ (IFN-γ) and macrophage inflammatory chemokine-2 (MIP-2) levels in bronchoalveolar lavage (BAL)-fluid were increased on all experimental days with exception of day 7 where MIP-2 concentrations dropped to control levels. In contrast, tumor necrosis factor-α (TNF-α) levels were only increased on day 7. From day 7 to 21 epithelial damage and secretory cell hypertrophy was observed. It is suggested that, the inflammatory cells/mediators, the epithelial damage and secretory cell hypertrophy contribute to initiation of airway hyperresponsiveness.Conclusion: Our study demonstrates for the first time that C. pneumoniae infection can modify bronchial responsiveness. This has clinical implications, since additional changes in airway responsiveness and inflammation-status induced by this bacterium may worsen and/or provoke breathlessness in asthma and COPD
Material-Specific Investigations of Correlated Electron Systems
We present the results of numerical studies for selected materials with
strongly correlated electrons using a combination of the local-density
approximation and dynamical mean-field theory (DMFT). For the solution of the
DMFT equations a continuous-time quantum Monte-Carlo algorithm was employed.
All simulations were performed on the supercomputer HLRB II at the Leibniz
Rechenzentrum in Munich. Specifically we have analyzed the pressure induced
metal-insulator transitions in Fe2O3 and NiS2, the charge susceptibility of the
fluctuating-valence elemental metal Yb, and the spectral properties of a
covalent band-insulator model which includes local electronic correlations.Comment: 14 pages, 7 figures, to appear in "High Performance Computing in
Science and Engineering, Garching 2009" (Springer
X-ray photoemission study of NiS_{2-x}Se_x (x = 0.0 - 1.2)
Electronic structure of NiS_{2-x}Se_x system has been investigated for
various compositions (x) using x-ray photoemission spectroscopy. An analysis of
the core level as well as the valence band spectra of NiS_2 in conjunction with
many-body cluster calculations provides a quantitative description of the
electronic structure of this compound. With increasing Se content, the on-site
Coulomb correlation strength (U) does not change, while the band width W of the
system increases, driving the system from a covalent insulating state to a
pd-metallic state.Comment: 19 pages, 6 figures, To appear in Phys. Rev. B, 200
Transcriptome sequencing of the Microarray Quality Control (MAQC) RNA reference samples using next generation sequencing
<p>Abstract</p> <p>Background</p> <p>Transcriptome sequencing using next-generation sequencing platforms will soon be competing with DNA microarray technologies for global gene expression analysis. As a preliminary evaluation of these promising technologies, we performed deep sequencing of cDNA synthesized from the Microarray Quality Control (MAQC) reference RNA samples using Roche's 454 Genome Sequencer FLX.</p> <p>Results</p> <p>We generated more that 3.6 million sequence reads of average length 250 bp for the MAQC A and B samples and introduced a data analysis pipeline for translating cDNA read counts into gene expression levels. Using BLAST, 90% of the reads mapped to the human genome and 64% of the reads mapped to the RefSeq database of well annotated genes with e-values ≤ 10<sup>-20</sup>. We measured gene expression levels in the A and B samples by counting the numbers of reads that mapped to individual RefSeq genes in multiple sequencing runs to evaluate the MAQC quality metrics for reproducibility, sensitivity, specificity, and accuracy and compared the results with DNA microarrays and Quantitative RT-PCR (QRTPCR) from the MAQC studies. In addition, 88% of the reads were successfully aligned directly to the human genome using the AceView alignment programs with an average 90% sequence similarity to identify 137,899 unique exon junctions, including 22,193 new exon junctions not yet contained in the RefSeq database.</p> <p>Conclusion</p> <p>Using the MAQC metrics for evaluating the performance of gene expression platforms, the ExpressSeq results for gene expression levels showed excellent reproducibility, sensitivity, and specificity that improved systematically with increasing shotgun sequencing depth, and quantitative accuracy that was comparable to DNA microarrays and QRTPCR. In addition, a careful mapping of the reads to the genome using the AceView alignment programs shed new light on the complexity of the human transcriptome including the discovery of thousands of new splice variants.</p
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