Differential Calculus on Manifolds with a Boundary. Applications

This paper contains a set of lecture notes on manifolds with boundary and corners, with particular attention to the space of quantum states. A geometrically inspired way of dealing with these kind of manifolds is presented,and explicit examples are given in order to clearly illustrate the main ideas.Comment: 42 pages, 6 figures, accepted for publication in International Journal of Geometric Methods in Modern Physic

Therapy of Canine Hyperlipidemia with Bezafibrate.

BackgroundBezafibrate (BZF) is effective in the treatment of hypertriglyceridemia in human patients, but there are no data on its use in dogs.ObjectiveTo assess the safety of BZF in hyperlipidemic dogs and its efficacy in decreasing serum triglyceride (TG) and cholesterol (CHO) concentrations.AnimalsForty-six dogs, 26 females and 20 males, mean (±SD) age of 9 (±3) years, with TG ≥150 mg/dL (33 dogs also were hypercholesterolemic [>300 mg/dL]).MethodsProspective, uncontrolled clinical trial. Dogs were treated with bezafibrate once daily, using 200 mg tablets at a dosage of 4-10 mg/kg (depending on body weight). Serum TG and CHO concentrations and alanine aminotransferase (ALT) and creatine kinase (CK) activity before and after 30 days of treatment were compared.ResultsSixteen dogs (34.8%) had primary hyperlipidemia, and 30 dogs (65.2%) had secondary hyperlipidemia (including spontaneous hyperadrenocorticism [41.3%, n = 19/46], chronic treatment with glucocorticoids [10.8%, n = 5/46], and hypothyroidism [15.2%, n = 7/46]). After 30 days, serum TG concentration normalized (<150 mg/dL) in 42 dogs (91.3%) and CHO concentration normalized (<270 mg/dL) in 22 of 33 dogs (66.7%). There was no difference in baseline TG concentration between the primary and secondary hyperlipidemia subgroups, but the decrease in TG concentration after treatment was greater in the primary hyperlipidemia subgroup. No adverse effects were observed, but ALT activity decreased significantly after 30 days of treatment.Conclusions and clinical importanceOver 30 days, BZF was safe and effective in treatment of primary and secondary hyperlipidemia in dogs

Análisis y diseño del sistema de riego de Capinota- Bolivia

Análisis y diseño del sistema de riego de Capinota proporciona una solución a corto plazo para solventar el problema de las fuertes sequías que afectan Capinota, una pequeña ciudad de Bolivia, donde más del 90% de la población se dedica al sector primario

A Pedagogical Intrinsic Approach to Relative Entropies as Potential Functions of Quantum Metrics: the qq-zz Family

The so-called $q$-z-\textit{R\'enyi Relative Entropies} provide a huge two-parameter family of relative entropies which includes almost all well-known examples of quantum relative entropies for suitable values of the parameters. In this paper we consider a log-regularized version of this family and use it as a family of potential functions to generate covariant $(0,2)$ symmetric tensors on the space of invertible quantum states in finite dimensions. The geometric formalism developed here allows us to obtain the explicit expressions of such tensor fields in terms of a basis of globally defined differential forms on a suitable unfolding space without the need to introduce a specific set of coordinates. To make the reader acquainted with the intrinsic formalism introduced, we first perform the computation for the qubit case, and then, we extend the computation of the metric-like tensors to a generic $n$-level system. By suitably varying the parameters $q$ and $z$, we are able to recover well-known examples of quantum metric tensors that, in our treatment, appear written in terms of globally defined geometrical objects that do not depend on the coordinates system used. In particular, we obtain a coordinate-free expression for the von Neumann-Umegaki metric, for the Bures metric and for the Wigner-Yanase metric in the arbitrary $n$-level case.Comment: 50 pages, 1 figur

La riscoperta della poena naturalis. note a margine di una recente questione di costituzionalità

Alla luce della recente questione di costituzionalità formulata dal Tribunale di Firenze in materia di poena naturalis, il contributo intende sviluppare alcune riflessioni più approfondite sulla sostanza giuridica di questo istituto, sulla rilevanza che lo stesso dovrebbe esser eventualmente chiamato ad assumere all’interno del nostro ordinamento costituzionale e sulle modalità attraverso le quali lo stesso potrebbe esser introdotto. Tutto ciò, ovviamente, senza trascurare di focalizzare l’attenzione anche sulle chance d’accoglimento che l’iniziativa assunta dal Tribunale di Firenze potrebbe avere e sui “passi falsi” che l’ordinanza di rimessione sembrerebbe aver compiuto

Límites y posibilidades del uso de algoritmos en la determinación de la previsibilidad (y evitabilidad) en los delitos imprudentes. ¿un posible correctivo a los sesgos cognitivos que afectan a este juicio?

Si la posibilidad de una alternancia entre el hombre y la máquina en la tarea de juzgar lleva a echarse a temblar, rechazar automáticamente toda herramienta que la tecnología pueda ofrecernos para esto sería situarse en una perspectiva «antihistórica». El objetivo de esta contribución será entonces comprender: a) si es técnica y jurídicamente posible un uso auxiliar de los algoritmos en el juicio de previsibilidad de la imprudencia; b) si realmente puede aportar alguna mejora, como reducir los sesgos y el «ruido» que suelen plagar esta clase de juicios; c) si una aplicación de la tecnología en este campo puede considerar-se deseable, o si no sería más conveniente seguir abogando por soluciones intrínsecamente «humanas

Art. 131 bis c.p. e colpa lieve

Il contributo si occupa, anche alla luce delle modifiche apportate al tenore della disposizione dalla “riforma Cartabia”, di verificare se e in che misura sia possibile far applicazione dell’art. 131-bis per rendere non punibili in via generale, già de iure condito, fatti caratterizzati da colpa lieve. A tal fine, vengono esaminati sia i possibili ostacoli applicativi che la disposizione pone sia le soluzioni interpretative che consentirebbero di superarli

Experimental estimation of entanglement at the quantum limit

Entanglement is the central resource of quantum information processing and the precise characterization of entangled states is a crucial issue for the development of quantum technologies. This leads to the necessity of a precise, experimental feasible measure of entanglement. Nevertheless, such measurements are limited both from experimental uncertainties and intrinsic quantum bounds. Here we present an experiment where the amount of entanglement of a family of two-qubit mixed photon states is estimated with the ultimate precision allowed by quantum mechanics.Comment: 4 pages, 3 figure

Optimal Operation Conditions for a Methane Fuelled SOFC and Microturbine Hybrid System

The study of a hybrid system obtained coupling a methane fuelled gas microturbine (MTG) and a solid oxide fuel cell (SOFC) was performed. The objective of this study is to evaluate the operation conditions as a function of the independent variables of the system, which are the current density and fuel utilization factor. Numerical simulations were carried out in developing a C++ computer code, in order to identify the preferable plant configuration and both the optimal methane flow and the current density. Operation conditions are able to ensure elasticity and the most suitable fuel utilization factor. To confirm the reliability of the models, results of the simulations were compared with reference results found in literature

Nutritional Properties of Milk from Dairy Ewes Fed with a Diet Containing Grape Pomace

Abstract: The aim of the present study was to evaluate the effects of a diet containing a 10% of grape pomace (GP) on the milk yield, chemical-nutritional characteristics, total phenolic compounds (TPCs), antioxidant activity (AOA), fatty acids and proteins profile of dairy ewe’s milk. Forty-six ewes were dived into two groups: a control group (Ctrl), fed a standard diet, and an experimental group (GP+), whose diet was supplemented with 10% of GP on dry matter. The trial lasted 60 days and milk samples were collected and analyzed at the beginning (T0) and after 60 (T60) days. Dietary enrichment with GP did not affect the yield and the chemical composition of the milk. TPCs and AOA were not affected by the diet. After 60 days, the diet induced an increase in monounsaturated fatty acids (MUFA) and a decrease in medium chain saturated fatty acids (MCSFA), but the total saturated fatty acids (SFA), polyunsaturated fatty acids (PUFA), short chain saturated fatty acids (SCSFA) and long chain saturated fatty acids (LCSFA) were not modified. A decrease in the C14 desaturation index and an increase in the C18 index were also detected. Total caseins and whey protein were not affected by GP, even if a lower content of k-casein in GP+ milk compared to Ctrl milk was observed on the 60th day. The results of the present study suggest that 10% of GP can be included in the diet of lactating ewes without modifying milk gross composition but inducing significantly changes the fatty acid profile