8,637 research outputs found
Effects of extended grazing during mid, late or throughout pregnancy, and winter shearing of housed ewes, on ewe and lamb performance
peer-reviewedA flock of March-lambing ewes was used to evaluate the effects of (i) extended (deferred, winter) grazing of pasture during mid, late or throughout pregnancy, and (ii) winter shearing of ewes housed during mid and late pregnancy, on lamb birth weight and subsequent growth to weaning. Ewes (n = 265) were allocated at random to five treatments for the period from 7 December (~ day 47 of pregnancy) to lambing. The treatments were: housed shorn (HS), housed unshorn (HU), grazing throughout
(EG), grazing to 20 January followed by housing (EGH), housed to 20 January followed by grazing (HEG). From 1 March to lambing the HEG and EG ewes were dispersed on the paddocks intended for grazing post lambing. All ewes were offered a concentrate supplement during the final 6 weeks of pregnancy. Housed ewes were offered grass silage while ewes on extended grazing were allocated 1.3 kg herbage dry matter per head per day from swards that had been closed for approximately 10 weeks. Ewes plus lambs (except triplet-rearing ewes which were grazed separately) from all treatments were grazed together post lambing, grouped according to lambing date. For treatments HS, HU, EGH, HEG and EG gestation lengths were 147.0, 145.6, 146.3, 146.6 and 146.9 (s.e. 0.34, P < 0.001) days, lamb birth weights were 4.9, 4.3, 4.4, 4.6 and 5.0 (s.e. 0.10, P < 0.001) kg, and lamb weaning weights were 34.6, 32.1, 33.3, 33.8 and 34.9 (s.e. 0.66, P < 0.001) kg, respectively. Extended grazing in mid and late pregnancy resulted in 35% and 65%, respectively, of the increase in lamb birth weight associated with extended grazing throughout. Treatment effects on lamb birth weight were associated with those on weaning weight (P < 0.01, R2 = 0.93). It is concluded that extended grazing or shearing of housed ewes increased lamb birth weight and subsequent weaning weight. The increased lamb birth weight from deferred grazing in mid pregnancy was probably due to improved protein utilisation from the grazed herbage. Meanwhile, the increase
An evaluation of two grassland-based systems of mid-season prime lamb production using prolific ewes of two genotypes
peer-reviewedA 4-year study was undertaken to evaluate the effects of two contrasting management
systems [year-round grazing (YRG) and normal seasonal grazing followed by indoor
feeding during winter (GWF)] on performance of mid-season lambing ewes. On the
GWF system, the annual stocking rate was 14.4 ewes/ha, grass silage was conserved
for winter feeding indoors, and the ewes were lambed indoors and were then turned
out to pasture. The YRG system was stocked at 10.5 ewes/ha, was grazed during the
winter, had outdoor lambing and the animals had access to all the farmlet for summer
grazing. The ewes were Belclare and Cheviot × Belclare which were balanced
across systems. Mean lambing dates and fertiliser N application rates were 20 and 30
March, and 85 and 92 kg/ha, for the GWF and YRG systems, respectively. Concentrate
supplementation during late pregnancy was similar on both systems. For the GWF and
YRG systems, litter size, lamb mortality, number of lambs reared, birth weight (kg),
weaning weight (kg) and lamb carcass output (kg/ha) were 2.17 and 2.24 (s.e. 0.038),
10.1 and 13.8% (P = 0.05), 1.77 and 1.78 (s.e. 0.042), 4.0 and 4.7 (s.e. 0.05, P < 0.001),
27.9 and 30.8 (s.e. 0.25, P < 0.001) and 469 and 348, respectively. Belclare ewes had a
higher litter size (2.34 v 2.07; s.e. 0.038, P < 0.001) and number of lambs reared per
ewe joined (1.86 v 1.69; s.e. 0.048, P < 0.01) than the Cheviot × Belclare ewes. There
were no significant interactions between system and ewe breed type. It is concluded that
the YRG system of prime lamb production was sustainable using prolific ewes but at
a reduced stocking rate (−26%) and with greater lamb mortality relative to the GWF
system. Ewe genotypes with a mean litter size of up to 2.34 lambs are suitable for both
systems. Lamb carcass output of 501 kg/ha was achieved from a primarily grass-based
system of mid-season prime lamb production using prolific ewes (Belclare)
Deep space network
Background, current status, and sites of Deep Space Network stations are briefly discussed
Development and flight tests of a Kalman filter for navigation during terminal area and landing operations
A Kalman filter for aircraft terminal area and landing navigation was implemented and flight tested in the NASA Ames STOLAND avionics computer onboard a Twin Otter aircraft. This system combines navaid measurements from TACAN, MODILS, air data, radar altimeter sensors along with measurements from strap-down accelerometer and attitude angle sensors. The flight test results demonstrate that the Kalman filter provides improved estimates of the aircraft position and velocity as compared with estimates from the more standard complementary filter. The onboard computer implementation requirements to achieve this improved performance are discussed
Nonlinear and adaptive estimation techniques in reentry
The development and testing of nonlinear and adaptive estimators for reentry (e.g. space shuttle) navigation and model parameter estimation or identification are reported. Of particular interest is the identifcation of vehicle lift and drag characteristics in real time. Several nonlinear filters were developed and simulated. Adaptive filters for the real time identification of vehicle lift and drag characteristics, and unmodelable acceleration, were also developed and tested by simulation. The simulations feature an uncertain system environment with rather arbitrary model errors, thus providing a definitive test of estimator performance. It was found that nonlinear effects are indeed significant in reentry trajectory estimation and a nonlinear filter is demonstrated which successfully tracks through nonlinearities without degrading the information content of the data. Under the same conditions the usual extended Kalman filter diverges and is useless. The J-adaptive filter is shown to successfully track errors in the modeled vehicle lift and drag characteristics. The same filter concept is also shown to track successfully through rather arbitrary model errors, including lift and drag errors, vehicle mass errors, atmospheric density errors, and wind gust errors
Tracking and data systems support for the Helios project. Volume 3: DSN support of Project Helios May 1976 - June 1977
Spacecraft extended mission coverage does not generally carry a high priority, but Helios was fortunate in that a combination of separated viewperiods and unique utilization of the STDN Goldstone antenna have provided a considerable amount of additional science data return, particularly at key times such a perihelion and/or solar occultation
Tracking and data systems support for the Helios project. Volume 2: DSN support of Project Helios April 1975 - May 1976
Deep Space Network activities in the development of the Helios B mission from planning through entry of Helios 2 into first superior conjunction (end of Mission Phase II) are summarized. Network operational support activities for Helios 1 from first superior conjunction through entry into third superior conjunction are included
Predicting the Starquakes in PSR J0537-6910
We report on more than 7 years of monitoring of PSR J0537-6910, the 16 ms
pulsar in the Large Magellanic Cloud, using data acquired with the RXTE. During
this campaign the pulsar experienced 23 sudden increases in frequency
(``glitches'') amounting to a total gain of over six ppm of rotation frequency
superposed on its gradual spindown of d(nu)/d(t) = -2e-10 Hz/s. The time
interval from one glitch to the next obeys a strong linear correlation to the
amplitude of the first glitch, with a mean slope of about 400 days ppm (6.5
days per uHz), such that these intervals can be predicted to within a few days,
an accuracy which has never before been seen in any other pulsar. There appears
to be an upper limit of ~40 uHz for the size of glitches in_all_ pulsars, with
the 1999 April glitch of J0537 as the largest so far. The change in the
spindown of J0537 across the glitches, Delta(d(nu)/d(t)), appears to have the
same hard lower limit of -1.5e-13 Hz/s, as, again, that observed in all other
pulsars. The spindown continues to increase in the long term,
d(d(nu)/d(t))/d(t) = -1e-21 Hz/s/s, and thus the timing age of J0537 (-0.5 nu
d(nu)/d(t)) continues to decrease at a rate of nearly one year every year,
consistent with movement of its magnetic moment away from its rotational axis
by one radian every 10,000 years, or about one meter per year. J0537 was likely
to have been born as a nearly-aligned rotator spinning at 75-80 Hz, with a
|d(nu)/d(t)| considerably smaller than its current value of 2e-10 Hz/s. The
pulse profile of J0537 consists of a single pulse which is found to be flat at
its peak for at least 0.02 cycles.Comment: 54 pages, 12 figures. Accepted for publication in The Astrophysical
Journal. Cleaner figure 2. V4 -- in line with version accepted by Ap
Hyperinsulinism-hyperammonaemia syndrome: novel mutations in the GLUD1 gene and genotype-phenotype correlations
Background: Activating mutations in the GLUD1 gene (which encodes for the intra-mitochondrial enzyme glutamate dehydrogenase, GDH) cause the hyperinsulinism–hyperammonaemia (HI/HA) syndrome. Patients present with HA and leucine-sensitive hypoglycaemia. GDH is regulated by another intra-mitochondrial enzyme sirtuin 4 (SIRT4). Sirt4 knockout mice demonstrate activation of GDH with increased amino acid-stimulated insulin secretion.
Objectives: To study the genotype–phenotype correlations in patients with GLUD1 mutations. To report the phenotype and functional analysis of a novel mutation (P436L) in the GLUD1 gene associated with the absence of HA.
Patients and methods: Twenty patients with HI from 16 families had mutational analysis of the GLUD1 gene in view of HA (n=19) or leucine sensitivity (n=1). Patients negative for a GLUD1 mutation had sequence analysis of the SIRT4 gene. Functional analysis of the novel P436L GLUD1 mutation was performed.
Results: Heterozygous missense mutations were detected in 15 patients with HI/HA, 2 of which are novel (N410D and D451V). In addition, a patient with a normal serum ammonia concentration (21 µmol/l) was heterozygous for a novel missense mutation P436L. Functional analysis of this mutation confirms that it is associated with a loss of GTP inhibition. Seizure disorder was common (43%) in our cohort of patients with a GLUD1 mutation. No mutations in the SIRT4 gene were identified.
Conclusion: Patients with HI due to mutations in the GLUD1 gene may have normal serum ammonia concentrations. Hence, GLUD1 mutational analysis may be indicated in patients with leucine sensitivity; even in the absence of HA. A high frequency of epilepsy (43%) was observed in our patients with GLUD1 mutations
Luminosity distance in Swiss cheese cosmology with randomized voids. II. Magnification probability distributions
We study the fluctuations in luminosity distances due to gravitational
lensing by large scale (> 35 Mpc) structures, specifically voids and sheets. We
use a simplified "Swiss cheese" model consisting of a \Lambda -CDM
Friedman-Robertson-Walker background in which a number of randomly distributed
non-overlapping spherical regions are replaced by mass compensating comoving
voids, each with a uniform density interior and a thin shell of matter on the
surface. We compute the distribution of magnitude shifts using a variant of the
method of Holz & Wald (1998), which includes the effect of lensing shear. The
standard deviation of this distribution is ~ 0.027 magnitudes and the mean is ~
0.003 magnitudes for voids of radius 35 Mpc, sources at redshift z_s=1.0, with
the voids chosen so that 90% of the mass is on the shell today. The standard
deviation varies from 0.005 to 0.06 magnitudes as we vary the void size, source
redshift, and fraction of mass on the shells today. If the shell walls are
given a finite thickness of ~ 1 Mpc, the standard deviation is reduced to ~
0.013 magnitudes. This standard deviation due to voids is a factor ~ 3 smaller
than that due to galaxy scale structures. We summarize our results in terms of
a fitting formula that is accurate to ~ 20%, and also build a simplified
analytic model that reproduces our results to within ~ 30%. Our model also
allows us to explore the domain of validity of weak lensing theory for voids.
We find that for 35 Mpc voids, corrections to the dispersion due to lens-lens
coupling are of order ~ 4%, and corrections to due shear are ~ 3%. Finally, we
estimate the bias due to source-lens clustering in our model to be negligible
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