107 research outputs found

    Information capacity of a single photon

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    Quantum states of light are the obvious choice for communicating quantum information. To date, encoding information into the polarization states of single photons has been widely used as these states form a natural closed two-state qubit. However, photons are able to encode much more - in principle, infinite - information via the continuous spatiotemporal degrees of freedom. Here we consider the information capacity of an optical quantum channel, such as an optical fiber, where a spectrally encoded single photon is the means of communication. We use the Holevo bound to calculate an upper bound on the channel capacity, and relate this to the spectral encoding basis and the spectral properties of the channel. Further, we derive analytic bounds on the capacity of such channels, and, in the case of a symmetric two-state encoding, calculate the exact capacity of the corresponding channel. © 2013 American Physical Society

    Security Limitations of Classical-Client Delegated Quantum Computing

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    Secure delegated quantum computing allows a computationally weak client to outsource an arbitrary quantum computation to an untrusted quantum server in a privacy-preserving manner. One of the promising candidates to achieve classical delegation of quantum computation is classical-client remote state preparation (RSPCCRSP_{CC}), where a client remotely prepares a quantum state using a classical channel. However, the privacy loss incurred by employing RSPCCRSP_{CC} as a sub-module is unclear. In this work, we investigate this question using the Constructive Cryptography framework by Maurer and Renner (ICS'11). We first identify the goal of RSPCCRSP_{CC} as the construction of ideal RSP resources from classical channels and then reveal the security limitations of using RSPCCRSP_{CC}. First, we uncover a fundamental relationship between constructing ideal RSP resources (from classical channels) and the task of cloning quantum states. Any classically constructed ideal RSP resource must leak to the server the full classical description (possibly in an encoded form) of the generated quantum state, even if we target computational security only. As a consequence, we find that the realization of common RSP resources, without weakening their guarantees drastically, is impossible due to the no-cloning theorem. Second, the above result does not rule out that a specific RSPCCRSP_{CC} protocol can replace the quantum channel at least in some contexts, such as the Universal Blind Quantum Computing (UBQC) protocol of Broadbent et al. (FOCS '09). However, we show that the resulting UBQC protocol cannot maintain its proven composable security as soon as RSPCCRSP_{CC} is used as a subroutine. Third, we show that replacing the quantum channel of the above UBQC protocol by the RSPCCRSP_{CC} protocol QFactory of Cojocaru et al. (Asiacrypt '19), preserves the weaker, game-based, security of UBQC.Comment: 40 pages, 12 figure

    Effect of dietary restriction and subsequent re-alimentation on the transcriptional profile of bovine ruminal epithelium

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    peer-reviewedCompensatory growth (CG) is utilised worldwide in beef production systems as a management approach to reduce feed costs. However the underlying biology regulating the expression of CG remains to be fully elucidated. The objective of this study was to examine the effect of dietary restriction and subsequent re-alimentation induced CG on the global gene expression profile of ruminal epithelial papillae. Holstein Friesian bulls (n = 60) were assigned to one of two groups: restricted feed allowance (RES; n = 30) for 125 days (Period 1) followed by ad libitum access to feed for 55 days (Period 2) or (ii) ad libitum access to feed throughout (ADLIB; n = 30). At the end of each period, 15 animals from each treatment were slaughtered and rumen papillae harvested. mRNA was isolated from all papillae samples collected. cDNA libraries were then prepared and sequenced. Resultant reads were subsequently analysed bioinformatically and differentially expressed genes (DEGs) are defined as having a Benjamini-Hochberg P value of <0.05. During re-alimentation in Period 2, RES animals displayed CG, growing at 1.8 times the rate of their ADLIB contemporary animals in Period 2 (P < 0.001). At the end of Period 1, 64 DEGs were identified between RES and ADLIB, with only one DEG identified at the end of Period 2. When analysed within RES treatment (RES, Period 2 v Period 1), 411 DEGs were evident. Genes identified as differentially expressed in response to both dietary restriction and subsequent CG included those involved in processes such as cellular interactions and transport, protein folding and gene expression, as well as immune response. This study provides an insight into the molecular mechanisms underlying the expression of CG in rumen papillae of cattle; however the results suggest that the role of the ruminal epithelium in supporting overall animal CG may have declined by day 55 of re-alimentation.SMW received financial assistance from Science Foundation Ireland (SFI) contract no 09/ RFP/GEN2447

    Multi-minicore Disease

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    Multi-minicore Disease (MmD) is a recessively inherited neuromuscular disorder characterized by multiple cores on muscle biopsy and clinical features of a congenital myopathy. Prevalence is unknown. Marked clinical variability corresponds to genetic heterogeneity: the most instantly recognizable classic phenotype characterized by spinal rigidity, early scoliosis and respiratory impairment is due to recessive mutations in the selenoprotein N (SEPN1) gene, whereas recessive mutations in the skeletal muscle ryanodine receptor (RYR1) gene have been associated with a wider range of clinical features comprising external ophthalmoplegia, distal weakness and wasting or predominant hip girdle involvement resembling central core disease (CCD). In the latter forms, there may also be a histopathologic continuum with CCD due to dominant RYR1 mutations, reflecting the common genetic background. Pathogenetic mechanisms of RYR1-related MmD are currently not well understood, but likely to involve altered excitability and/or changes in calcium homeoestasis; calcium-binding motifs within the selenoprotein N protein also suggest a possible role in calcium handling. The diagnosis of MmD is based on the presence of suggestive clinical features and multiple cores on muscle biopsy; muscle MRI may aid genetic testing as patterns of selective muscle involvement are distinct depending on the genetic background. Mutational analysis of the RYR1 or the SEPN1 gene may provide genetic confirmation of the diagnosis. Management is mainly supportive and has to address the risk of marked respiratory impairment in SEPN1-related MmD and the possibility of malignant hyperthermia susceptibility in RYR1-related forms. In the majority of patients, weakness is static or only slowly progressive, with the degree of respiratory impairment being the most important prognostic factor

    Behavioral genetics and taste

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    This review focuses on behavioral genetic studies of sweet, umami, bitter and salt taste responses in mammals. Studies involving mouse inbred strain comparisons and genetic analyses, and their impact on elucidation of taste receptors and transduction mechanisms are discussed. Finally, the effect of genetic variation in taste responsiveness on complex traits such as drug intake is considered. Recent advances in development of genomic resources make behavioral genetics a powerful approach for understanding mechanisms of taste

    Control of adult neurogenesis by programmed cell death in the mammalian brain

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    Effects of perceived cost, service quality, and customer satisfaction on health insurance service continuance

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    This paper aims to contribute to the universal discourse on financial services continuance behavior by examining the impact of service cost on customers\u27 service-quality perception and service continuance intention. It presents the results of an empirical study that has explored the impacts of service cost, service quality, and customer satisfaction on health insurance customers\u27 behavioral intention toward continuing or discontinuing with their service providers. Very few studies had examined the impact of service cost on service-quality perception. Our study attempts to fill that gap. A sample of 820 customers was surveyed, and 624 usable responses were analyzed with ANOVA, standard multiple regression, and logistic regression. Our findings indicate that, although highly satisfied health insurance customers will most likely retain their current service providers, customer dissatisfaction does not necessarily lead to discontinuance. Our results also provide some operational implications for health insurance managers, with strategies for reducing attrition and improving customer retention
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