A Survey of Semantic Integration Approaches in Bioinformatics

Technological advances of computer science and data analysis are helping to provide continuously huge volumes of biological data, which are available on the web. Such advances involve and require powerful techniques for data integration to extract pertinent knowledge and information for a specific question. Biomedical exploration of these big data often requires the use of complex queries across multiple autonomous, heterogeneous and distributed data sources. Semantic integration is an active area of research in several disciplines, such as databases, information-integration, and ontology. We provide a survey of some approaches and techniques for integrating biological data, we focus on those developed in the ontology community

TRANSLATION METHODOLOGY BASED ON META- MODEL OF COMPLEX STRUCTURE FOR DATABASE DESIGN

ABSTRACT We propose a software layer called GUEDOS-DB upon Object-Relational Database Management System ORDMS. In this work we apply it in Molecular Biology, more precisely Organelle (mitochondria and chloroplasts) complete genome. We aim to offer biologists the possibility to access in a unified way information spread among heterogeneous genome databanks. In this paper, the goal is firstly, to provide a visual schema graph through a number of illustrative examples. The adopted, human-computer interaction technique in this visual designing and querying makes very easy for biologists to formulate database queries compared with linear textual query representation

Mesure sélective des temps de relaxation T2 des lipides intra et extramyocytaires chez le rat Zucker à 7 teslas

articl

Measurement of nonlinear pO 2 decay in mouse lungs using 3 He-MRI

ABSTRACT: Spatial and temporal variations in oxygen partial pressure ( pO 2 ) during breath-hold can be exploited to obtain important regional parameters of lung function. In the course of apnea, the oxygen concentration is known to decay exponentially. Therefore, the initial pO 2 ( p 0 ) can be used to represent local ventilation, and the oxygen depletion time constant can characterize perfusion. The protocol, based on a nonlinear model of pO 2 decay, was validated in six healthy mice. Parametric maps of p 0 and oxygen depletion time constant were obtained for pure He/air mixture, in agreement with physiology

In vivo assessment of mouse hindleg intramyocellular lipids by 1H-MR spectroscopy

articl

Mesure selective des temps de relaxation T2 des lipides intra et extramyocytaires chez le rat Zucker a 7 teslas

articl

Nonlinear pO(2) decay in mouse lungs using He-3-MRI

articl

Alveolar pO2 and oxygen uptake imaging in mice using 3He-MRI

articl

Measurement of nonlinear decay of alveolar partial pressure of oxygen in mice using 3He-MR

International audienc

Intramyocellular lipid variations in active older men: relationship with aerobic fitness

International audienceAIMS:Intramyocellular lipid (IMCL) variations in older men are poorly explored. In young adults, IMCL can be influenced by both diet and exercise interventions; this flexibility is related to aerobic fitness. We evaluated in active older adults the influence of maximal aerobic capacity on short-term diet and exercise-induced variations in IMCL stores