Extending the Service-Life of Bridges using Sustainable and Resilient Abutment Systems: An Experimental Approach to Electrochemical Characterization of Lightweight Mechanically Stabilized Earth

Bridges are critical components of transportation infrastructure. This research addresses the need to extend the service life of bridges by improving the safety and reliability of bridge abutments and reducing their life-cycle cost and footprints. Mechanically stabilized earth (MSE) is a known strategy to enhance the economy and performance of bridge abutments. In addition, the application of rotary-kiln-manufactured lightweight aggregate backfills improves the performance of MSE bridge abutments with a leaner structural system. Such improvements include a reduction of structural demands due to a lower density, free drainage of granular materials, a high internal friction angle, less settlement with no consolidation, and accelerated construction requiring less compaction effort. This project aims to assess the electrochemical properties of expanded shale, clay, and slate (ESCS) aggregates and their influence on the corrosion of embedded steel strips. The experimental methodology involves evaluating current testing methods to measure electrical resistivity, pH, sulfate, chloride, and corrosion considering various gradation, moisture, dilution, and curing conditions. Samples represent available sources of ESCS with one source of normal weight aggregates for comparison. Results indicate the appropriateness of ESCS for addressing corrosion in MSE backfills. Further, outcomes provide guidelines to categorically predict the corrosivity of steel reinforcement when ESCS is employed as fill within MSE systems. These guidelines can help optimize the design and reduce the need to maintain and rehabilitate bridges, abutments, and approach and departure slabs on roadways to keep transportation systems safe and cost-efficient for sustainable infrastructure

Boat scarring effects on submerged aquatic vegetation in Virginia (year 1)

Submerged Aquatic Vegetation (SAV) in Chesapeake Bay has received significant attention in recent decades due to increasing understanding of the importance of these habitats for ecological functions, including fisheries habitat. Yet, SAV in many regions of the bay are at some of the lowest levels of abundance in recorded history. This has led state management agencies to adopt numerous policies and regulations to protect and restore these valuable communities. The Chesapeake Bay 2000 Agreement highlights SAV by recommitting to the goal of protecting and restoring 114,000 acres, revising existing restoration goals and strategies by 2002, and implementing a strategy to protect and restore SAV by 2002 (Chesapeake Executive Council, 2000). In addition to addressing water quality issues, which are considered the major cause of SAV changes in distribution and abundance, there is increasing concern regarding how direct human impacts such as dredging and boating are affecting SAV. Aerial photography taken annually for monitoring SAV populations baywide has shown evidence of one form of human-induced damage--boat scarring. We therefore more closely examined photographs taken between 1987 and 2000 to evaluate this disturbance. Scarred sites were identified and assessed for key characteristics including intensity, orientation to shoreline, and scar curvature at each site. In addition Virginia Marine Resources Commission (VMRC) enforcement personnel were surveyed for qualitative information on the occurrence of recreational and commercial fishing activities in Virginia’s waters in the vicinity of SAV beds. Aeria

Pressure-driven high-to-low spin transition in the bimetallic quantum magnet [Ru2(O2CMe)4]3[Cr(CN)6]

Synchrotron-based infrared and Raman spectroscopies were brought together with diamond anvil cell techniques and an analysis of the magnetic properties to investigate the pressure-induced high → low spin transition in [Ru2(O2CMe)4]3[Cr(CN)6]. The extended nature of the diruthenium wave function combined with coupling to chromium-related local lattice distortions changes the relative energies of the π ∗ and δ ∗ orbitals and drives the high → low spin transition on the mixed-valence diruthenium complex. This is a rare example of an externally controlled metamagnetic transition in which both spin-orbit and spin-lattice interactions contribute to the mechanism

Comparison of urinary 6‐β‐cortisol and the erythromycin breath test as measures of hepatic P450IIIA (CYP3A) activity

Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/110077/1/cptclpt1992140.pd

Ovarian Cancer Classification based on Mass Spectrometry Analysis of Sera

In our previous study [1], we have compared the performance of a number of widely used discrimination methods for classifying ovarian cancer using Matrix Assisted Laser Desorption Ionization (MALDI) mass spectrometry data on serum samples obtained from Reflectron mode. Our results demonstrate good performance with a random forest classifier. In this follow-up study, to improve the molecular classification power of the MALDI platform for ovarian cancer disease, we expanded the mass range of the MS data by adding data acquired in Linear mode and evaluated the resultant decrease in classification error. A general statistical framework is proposed to obtain unbiased classification error estimates and to analyze the effects of sample size and number of selected m/z features on classification errors. We also emphasize the importance of combining biological knowledge and statistical analysis to obtain both biologically and statistically sound results

Harmonic analysis of the cone flicker ERG of rabbit

This paper is not subject to U.S. copyright. The definitive version was published in Experimental Eye Research 91 (2010): 811-817, doi:10.1016/j.exer.2010.10.005.Harmonic analysis was used to characterize the rabbit flicker ERG elicited by sinusoidally modulated full-field stimuli under light-adapted conditions. The frequency-response function for fundamental amplitude, derived from Fourier analysis of the ERG waveforms, exhibited two limbs, with an amplitude minimum at approximately 30 Hz, and a high-frequency region peaking at around 45 Hz and extending to more than 100 Hz at higher adapting levels. At low frequencies (<20 Hz), the fundamental response amplitude was independent of mean luminance (Weber law behavior), whereas the response amplitude at high stimulus frequencies varied nonlinearly with mean luminance. At low frequencies, intravitreal administration of L-AP4, which blocks ON-pathway activity, reduced the fundamental response amplitude and produced a phase shift. On the other hand, PDA, which reduces OFF-pathway activity, had a minimal effect on both the response amplitude and phase at low frequencies. At high frequencies, L-AP4 increased the fundamental response amplitude at low mean luminances, whereas PDA had only a small effect on amplitude and phase. Both pharmacologic agents removed the minimum in the amplitude-frequency function as well as the abrupt change in phase at stimulus frequencies near 30 Hz. The results suggest that there is a nonlinear interaction between ON- and OFF-pathway activity over the entire stimulus frequency range examined in this study. These findings provide a basis for formulating protocols to evaluate the effect of pharmacologic agents and/or disease on the cone flicker ERG of rabbit.This work was supported by a grant from the Joyce Schroeder Fund (HQ), NIH research grant EY008301 (KRA), NIH core grant EY01792, RPB Senior Scientific Investigator Award (HR) and an unrestricted departmental award from Research to Prevent Blindness, Inc

Extending the Service-Life of Bridges Using Sustainable and Resilient Abutment Systems: An Experimental Approach to the Electrochemical Characterization of Lightweight Mechanically Stabilized Earth

ZSB12017-SJAUXBridges are critical components of transportation infrastructure. This research addresses the need to extend the service life of bridges by improving the safety and reliability of bridge abutments and reducing their life-cycle cost and footprints. Mechanically stabilized earth (MSE) is a known strategy to enhance the economy and performance of bridge abutments. In addition, the application of rotary-kiln-manufactured lightweight aggregate backfills improves the performance of MSE bridge abutments with a leaner structural system. Such improvements include a reduction of structural demands due to a lower density, free drainage of granular materials, a high internal friction angle, less settlement with no consolidation, and accelerated construction requiring less compaction effort. This project aims to assess the electrochemical properties of expanded shale, clay, and slate (ESCS) aggregates and their influence on the corrosion of embedded steel strips. The experimental methodology involves evaluating current testing methods to measure electrical resistivity, pH, sulfate, chloride, and corrosion considering various gradation, moisture, dilution, and curing conditions. Samples represent available sources of ESCS with one source of normal weight aggregates for comparison. Results indicate the appropriateness of ESCS for addressing corrosion in MSE backfills. Further, outcomes provide guidelines to categorically predict the corrosivity of steel reinforcement when ESCS is employed as fill within MSE systems. These guidelines can help optimize the design and reduce the need to maintain and rehabilitate bridges, abutments, and approach and departure slabs on roadways to keep transportation systems safe and costefficient for sustainable infrastructure