Image based tracking approaches to AR/C at the Johnson Space Center

Automated Rendezvous and Capture (AR&C) requires the determination of the six degrees of freedom relating two free bodies. Sensor systems that can provide such information have varying sizes, weights, power requirements, complexities and accuracies. One type of sensor system which can provide several key advantages is an image based tracking system, or better known as a machine vision system. By image based tracking we mean that the sensor is some imaging device such as one or more video cameras, from which the tracking parameters necessary to support the rendezvous and capture operations (range, attitude, etc.) can be derived. Image based tracking offers many advantages such as relative hardware simplicity and reprogrammability. These advantages must be weighed against the disadvantages of these systems, such as limited operational range, poorer accuracy at greater distances and sensitivity to lighting conditions. However, with properly designed algorithms and targets these disadvantages can be minimized for many important applications. Rigorous testing in realistic environments can further increase the robustness and reliability of these systems. This presentation describes the facilities used at JSC to support AR&C image based tracking development and the details of our binocular stereo approach to image based tracking

A binocular stereo approach to AR/C at the Johnson Space Center

Automated Rendezvous and Capture requires the determination of the 6 DOF relating two free bodies. Sensor systems that can provide such information have varying sizes, weights, power requirements, complexities, and accuracies. One type of sensor system that can provide several key advantages is a binocular stereo vision system

Programmable remapper with single flow architecture

The invention relates to image processing systems and methods and in particular to a machine which accepts a real time video image in the form of a matrix of picture elements (pixels) and remaps such image according to a selectable one of a plurality of mapping functions to create an output matrix of pixels. Such mapping functions, or transformations, may be any one of a number of different transformations depending on the objective of the user of the system. The system remaps input images from one coordinate system to another using a set of look-up tables for the data necessary for the transform. The transforms, which are operator selectable, are precomputed and loaded into massive look-up tables. Input pixels, via the look-up tables of any particular transform selected, are mapped into output pixels with the radiance information of the input pixels being appropriately weighted. An earlier embodiment of the system included two parallel processors: a collective processor which mapped multiple input pixels into a single output pixel and an interpolative processor. The interpolative processor performed an interpolation among pixels in the input image where a given input pixel may affect the value of many output pixels. Several advantages are provided over previous embodiments in that the two distinct processors are replaced by a single processor capable of performing both types of operations (collective and interpolative) with no more complexity. Previously, there has existed no image processor or 'remapper' that can operate with sufficient speed and flexibility to permit investigating different transformation patterns in real time

Human Rating the Orion Parachute System

Human rating begins with design. Converging on the requirements and identifying the risks as early as possible in the design process is essential. Understanding of the interaction between the recovery system and the spacecraft will in large part dictate the achievable reliability of the final design. Component and complete system full-scale flight testing is critical to assure a realistic evaluation of the performance and reliability of the parachute system. However, because testing is so often difficult and expensive, comprehensive analysis of test results and correlation to accurate modeling completes the human rating process. The National Aeronautics and Space Administration (NASA) Orion program uses parachutes to stabilize and decelerate the Crew Exploration Vehicle (CEV) spacecraft during subsonic flight in order to deliver a safe water landing. This paper describes the approach that CEV Parachute Assembly System (CPAS) will take to human rate the parachute recovery system for the CEV

FOXD3 Regulates VISTA Expression in Melanoma.

Immune checkpoint inhibitors have improved patient survival in melanoma, but the innate resistance of many patients necessitates the investigation of alternative immune targets. Many immune checkpoint proteins lack proper characterization, including V-domain Ig suppressor of T cell activation (VISTA). VISTA expression on immune cells can suppress T cell activity; however, few studies have investigated its expression and regulation in cancer cells. In this study, we observe that VISTA is expressed in melanoma patient samples and cell lines. Tumor cell-specific expression of VISTA promotes tumor onset in vivo, associated with increased intratumoral T regulatory cells, and enhanced PDL-1 expression on tumor-infiltrating macrophages. VISTA transcript levels are regulated by the stemness factor Forkhead box D3 (FOXD3). BRAF inhibition upregulates FOXD3 and reduces VISTA expression. Overall, this study demonstrates melanoma cell expression of VISTA and its regulation by FOXD3, contributing to the rationale for therapeutic strategies that combine targeted inhibitors with immune checkpoint blockade

A new method reveals microtubule minus ends throughout the meiotic spindle

Anastral meiotic spindles are thought to be organized differently from astral mitotic spindles, but the field lacks the basic structural information required to describe and model them, including the location of microtubule-nucleating sites and minus ends. We measured the distributions of oriented microtubules in metaphase anastral spindles in Xenopus laevis extracts by fluorescence speckle microscopy and cross-correlation analysis. We localized plus ends by tubulin incorporation and combined this with the orientation data to infer the localization of minus ends. We found that minus ends are localized throughout the spindle, sparsely at the equator and at higher concentrations near the poles. Based on these data, we propose a model for maintenance of the metaphase steady-state that depends on continuous nucleation of microtubules near chromatin, followed by sorting and outward transport of stabilized minus ends, and, eventually, their loss near poles

The association of dyslexia and developmental speech and language disorder candidate genes with reading and language abilities in adults

Reading and language abilities are critical for educational achievement and success in adulthood. Variation in these traits is highly heritable, but the underlying genetic architecture is largely undiscovered. Genetic studies of reading and language skills traditionally focus on children with developmental disorders; however, much larger unselected adult samples are available, increasing power to identify associations with specific genetic variants of small effect size. We introduce an Australian adult population cohort (41.7–73.2 years of age, N = 1505) in which we obtained data using validated measures of several aspects of reading and language abilities. We performed genetic association analysis for a reading and spelling composite score, nonword reading (assessing phonological processing: a core component in learning to read), phonetic spelling, self-reported reading impairment and nonword repetition (a marker of language ability). Given the limited power in a sample of this size (~80% power to find a minimum effect size of 0.005), we focused on analyzing candidate genes that have been associated with dyslexia and developmental speech and language disorders in prior studies. In gene-based tests, FOXP2, a gene implicated in speech/language disorders, was associated with nonword repetition (p < .001), phonetic spelling (p = .002) and the reading and spelling composite score (p < .001). Gene-set analyses of candidate dyslexia and speech/language disorder genes were not significant. These findings contribute to the assessment of genetic associations in reading and language disorders, crucial for understanding their etiology and informing intervention strategies, and validate the approach of using unselected adult samples for gene discovery in language and reading

Quantum quench spectroscopy of a Luttinger liquid: Ultrarelativistic density wave dynamics due to fractionalization in an XXZ chain

We compute the dynamics of localized excitations produced by a quantum quench in the spin 1/2 XXZ chain. Using numerics combining the density matrix renormalization group and exact time evolution, as well as analytical arguments, we show that fractionalization due to interactions in the pre-quench state gives rise to "ultrarelativistic" density waves that travel at the maximum band velocity. The system is initially prepared in the ground state of the chain within the gapless XY phase, which admits a Luttinger liquid (LL) description at low energies and long wavelengths. The Hamiltonian is then suddenly quenched to a band insulator, after which the chain evolves unitarily. Through the gapped dispersion of the insulator spectrum, the post-quench dynamics serve as a "velocity microscope," revealing initial state particle correlations via space time density propagation. We show that the ultrarelativistic wave production is tied to the particular way in which fractionalization evades Pauli-blocking in the zero-temperature initial LL state.Comment: 32 pages, 27 figures; v2: references update