67 research outputs found
Sequential change of DNA synthesis in cultured aortic smooth muscle cells stimulated by hyperlipidemic serum
Effect of hyperlipidemic serum and irradiation on wound healing in primary quiescent cultures of vascular cells
ANTIATHEROMATOUS PROPERTIES OF ELASTASE IN CHOLESTEROL-FED RABBITS and EX VIVO SUPPRESSIVE EFFECT OF ELASTASE ON SMOOTH MUSCLE CELL PROLIFERATION IN THE PRESENCE OF HYPERCHOLESTEROLEMIA
GROWTH OF RABBIT AORTIC SMOOTH MUSCLE CELLS IN SERUM FROM PATIENTS WITH JUVENILE DIABETES
The Latest Evidence, in vitro and in vivo, on Controlling Smooth Muscle Cell Proliferation and Arterial Wall Cholesterol Ester Accumulation by Controlling LDL Concentration
Sympathetic neurotransmission in the rabbit isolated central ear artery is affected as early as one week following a single dose of X-irradiation
1. The short-term effect of a single dose of 4500 rad X-irradiation on sympathetic neurotransmission (involving both noradrenergic and purinergic components) was assessed in the rabbit central ear artery, 1, 4 and 6 weeks post-irradiation. 2. Neurally mediated contractions were reduced as early as 1 week post-irradiation, with responses to lower frequency stimulation being initially most affected. This suggest that the purinergic component of the contractile response is affected earlier than the adrenergic component. 3. There was no change in the amplitude or sensitivity of treated preparations to the cumulative application of noradrenaline when compared with untreated preparations. In contrast, contractions to alpha, beta-methylene ATP (1 microM), a P2-purinoceptor agonist, were significantly increased at 4 and 6 weeks post-irradiation, although not at 1 week post-irradiation. 4. There were no apparent changes in the pattern of catecholamine fluorescence as a result of irradiation. However, the tissue content of noradrenaline was significantly reduced 6 weeks post-irradiation when compared with control preparations. 5. It is concluded that damage to sympathetic cotransmission is one of the early effects of irradiation, with initial impairment predominantly of the purinergic component
Ultrastructural morphometry of cultivated smooth muscle cells from normotensive and hypertensive rats
Stimulation of proliferation in stationary primary cultures of monkey and rabbit aortic smooth muscle cells
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