White Organic Light-Emitting Diodes with fine chromaticity tuning via ultrathin layer position shifting

Non-doped white organic light-emitting diodes using an ultrathin yellow-emitting layer of rubrene (5,6,11,12-tetraphenylnaphtacene) inserted on either side of the interface between a hole-transporting NPB (4,4'-bis[N-(1-naphtyl)-N-phenylamino]biphenyl) layer and a blue-emitting DPVBi (4,4'-bis(2,2'-diphenylvinyl)-1,1'-biphenyl) layer are described. Both the thickness and the position of the rubrene layer allow fine chromaticity tuning from deep-blue to pure-yellow via bright-white with CIE coordinates (x= 0.33, y= 0.32), a external quantum efficiency of 1.9%, and a color rendering index of 70. Such a structure also provides an accurate sensing tool to measure the exciton diffusion length in both DPVBi and NPB (8.7 and 4.9 nm respectively)

The dynamics of volunteer motivations for engaging in the management of invasive plants : Insights from a mixed-methods study on Scottish seabird islands

Acknowledgments The authors thank the SOS Puffin volunteers and the Craigleith Management Group for their support in this research project. We also thank John Hunt (SOS Puffin), Anja Byg and Kerry Waylen (The James Hutton Institute), Norman Dandy (Plunkett Foundation), Michelle Pinard (University of Aberdeen), and four anonymous reviewers for their valuable comments on earlier versions of this paper. We acknowledge funding by the Natural Environment Research Council and the Rivers and Fisheries Trusts of Scotland. (NERC).Peer reviewedPostprin

Seasonal variability of resources : The unexplored adversary of biogas use in rural Ethiopia

Funding This project was funded by (BBSRC BB/M010996/1) and the University of Aberdeen. AF’s contribution was supported by UKRI (ES/P002501/1). JS’s contribution was supported by UKRI (ES/P002501/1) and DFID NEXUS (NE/P004830). Acknowledgements We would like to thank Hawassa University and the Southern Agricultural Research Institute for their support with organisation, data collection and translation.Peer reviewedPublisher PD

Increasing the Productivity of Laser Powder Bed Fusion for Stainless Steel 316L through Increased Layer Thickness

Additive manufacturing (AM) is able to generate parts of a quality comparable to those produced through conventional manufacturing, but most of the AM processes are associated with low build speeds, which reduce the overall productivity. This paper evaluates how increasing the powder layer thickness from 20 \ub5m to 80 \ub5m affects the build speed, microstructure and mechanical properties of stainless steel 316L parts that are produced using laser powder bed fusion. A detailed microstructure characterization was performed using scanning electron microscopy, electron backscatter diffraction, and x-ray powder diffraction in conjunction with tensile testing. The results suggest that parts can be fabricated four times faster with tensile strengths comparable to those obtained using standard process parameters. In either case, nominal relative density of > 99.9% is obtained but with the 80 \ub5m layer thickness presenting some lack of fusion defects, which resulted in a reduced elongation to fracture. Still, acceptable yield strength and ultimate tensile strength values of 464 MPa and 605 MPa were obtained, and the average elongation to fracture was 44%, indicating that desirable properties can be achieved

Empowered communities or "cheap labour"? : Engaging volunteers in the rationalised management of invasive alien species in Great Britain

The authors would like to thank all the organisations and volunteers who participated in this study, as well as Anja Byg, Kerry Waylen, Michelle Pinard, Norman Dandy and three anonymous reviewers for their valuable comments on earlier versions of this paper. We acknowledge funding by the Natural Environment Research Council and the Rivers and Fisheries Trusts of Scotland (NERC-CASE PhD scholarship 12994499) and support by the Rural & Environment Science and Analytical Services Division of the Scottish Government.Peer reviewedPostprin

Update on the current status of onchocerciasis in Cote d’Ivoire following 40 years of intervention: Progress and challenges

Background Onchocerciasis control in Côte d’Ivoire started with aerial insecticide spraying in 1974 and continued with community directed treatment with ivermectin (CDTi) from 1992 to the present. Onchocerciasis and lymphatic filariasis (LF) are co-endemic in 46 of the 81 health districts in the country. Fourteen and 12 districts are endemic for only LF or onchocerciasis, respectively. This paper aims to review the impact of past interventions on onchocerciasis in Côte d’Ivoire between 1975 and 2013, and review plans for disease elimination. Methods We reviewed microfilaria (MF, skin snip) prevalence and community microfilarial load (CMFL) data from published reports from 53 health districts during two major epidemiological assessment periods. Data from 1975 through 1991 provided information on the impact of vector control, and data from 1992 through 2016 provided information on the impact of CDTi. Results Weekly aerial insecticide spraying in 8 endemic districts between 1975 and 1991 reduced the overall MF prevalence by 68.1% from 43.5% to 13.9%. The CMFL also decreased in 7 out of 8 surveyed communities by 95.2% from 9.24 MF/snip to 0.44 MF/snip. Ivermectin distribution started in 1992. The coverage targets for control (65% of the total population) was reached in most endemic districts, and some areas achieved 80% coverage. Two sets of surveys were conducted to assess the impact of CDTi. Results from the first repeat surveys showed a significant decrease in overall MF prevalence (by 75.7%, from 41.6% to 10.1%). The second follow-up evaluation showed further improvement in most endemic districts and also documented major reductions in CMFL compared to baseline. Conclusions Extensive data collected over many years document the very significant impact of interventions conducted by the National Onchocerciasis and other Eyes Diseases Control Programme during challenging times with periods of civil unrest. The Health Ministry has now integrated efforts to control neglected tropical diseases and adopted the goal of onchocerciasis elimination

PfHPRT: a new biomarker candidate of acute Plasmodium falciparum infection.

Plasmodium falciparum is a protozoan parasite that causes human malaria. This parasitic infection accounts for approximately 655,000 deaths each year worldwide. Most deaths could be prevented by diagnosing and treating malaria promptly. To date, few parasite proteins have been developed into rapid diagnostic tools. We have combined a shotgun and a targeted proteomic strategy to characterize the plasma proteome of Gambian children with severe malaria (SM), mild malaria, and convalescent controls in search of new candidate biomarkers. Here we report four P. falciparum proteins with a high level of confidence in SM patients, namely, PF10_0121 (hypoxanthine phosphoribosyltransferase, pHPRT), PF11_0208 (phosphoglycerate mutase, pPGM), PF13_0141 (lactate dehydrogenase, pLDH), and PF14_0425 (fructose bisphosphate aldolase, pFBPA). We have optimized selected reaction monitoring (SRM) assays to quantify these proteins in individual patients. All P. falciparum proteins were higher in SM compared with mild cases or control subjects. SRM-based measurements correlated markedly with clinical anemia (low blood hemoglobin concentration), and pLDH and pFBPA were significantly correlated with higher P. falciparum parasitemia. These findings suggest that pHPRT is a promising biomarker to diagnose P. falciparum malaria infection. The diagnostic performance of this marker should be validated prospectively