‘Good Building’: Bertolt Brecht’s Utopian Historical Optimism at the End of World War II

The article focuses on the works of Bertolt Brecht which depicts his insights regarding the reconstruction of Germany. Such works include the story "The City Builder" and the plays "Caucasian Chalk Circle" and "The Days of the Commune." It discusses his principles of what he considers as good building as well as the three criteria addressed in good building which include size, time, and beauty

Meta-Design: A Conceptual Framework for End-User Software Engineering

In a world that is not predictable, improvisation, evolution, and innovation are more than a luxury: they are a necessity. The challenge of design is not a matter of getting rid of the emergent, but rather of including it and making it an opportunity for more creative and more adequate solutions to problems. Meta-design is an emerging conceptual framework aimed at defining and creating social and technical infrastructures in which new forms of collaborative design can take place. It extends the traditional notion of system design beyond the original development of a system. It is grounded in the basic assumption that future uses and problems cannot be completely anticipated at design time, when a system is developed. Users, at use time, will discover mismatches between their needs and the support that an existing system can provide for them. These mismatches will lead to breakdowns that serve as potential sources of new insights, new knowledge, and new understanding

The Governor-General's Apology: Reflections on Anzac Day

In September 1999, the then governor-general of Australia, Sir William Deane, gave a speech to the Australian Conference on Lutheran Education where he offered an apology to members of the German Australian community for the 'tragic, and often shameful, discrimination against Australians of German origin fostered during the world wars'. This article reflects on a number of issues raised by the Governor-General's statement, most importantly on our understanding of the Anzac historiography and its various narratives

Using recommendations to help novices to reuse design knowledge

This is the author's accepted manuscript. The final publication is available at Springer via http://dx.doi.org/10.1007/978-3-642-21530-8_35. Copyright @ Springer 2011.The use of pattern languages is not so straightforward since its users have to identify the patterns they need, browsing the language and understanding both the benefits and trade-offs of each pattern as well as the relations and interactions it has with other patterns. Novice designers might benefit from tools that assist them in this learning task. In this paper we describe a recommendation tool embedded in a visual environment for pattern-based design which aims at suggesting patterns to help novice designers to produce better designs and understand the language.Spanish Ministry of Science and Innovatio

The Timing of Unemployment Response in Austrian Regional Labour Markets

Series: Discussion Papers of the Institute for Economic Geography and GIScienc

Promiscuidad, emancipación, sumisión: El proceso educador y el establecimiento de un modelo de actuación femenino en la historia marco de la 1001 noches.

Sin resume

Alternative modulation of protein-protein interactions by small molecules.

Protein-protein interactions (PPI) have become increasingly popular drug targets, with a number of promising compounds currently in clinical trials. Recent research shows, that PPIs can be modulated in more ways than direct inhibition, where novel non-competitive modes of action promise a solution for the difficult nature of PPI drug discovery. Here, we review recently discovered PPI modulators in light of their mode of action and categorise them as disrupting versus stabilising, orthosteric versus allosteric and by their ability to affect the proteins' dynamics. We also give recent examples of compounds successful in the clinic, analyse their physicochemical properties and discuss how to overcome the hurdles in discovering alternative modes of modulation.This work was supported by Wellcome Trust Strategic Award Grant (090340/Z/09/Z).This is the final published version. It first appeared with a CC BY licence at http://www.sciencedirect.com/science/article/pii/S0958166915000695#