Hard sphere-like dynamics in a non hard sphere liquid

The collective dynamics of liquid Gallium close to the melting point has been studied using Inelastic X-ray Scattering to probe lengthscales smaller than the size of the first coordination shell. %(momentum transfers, $Q$, $>$15 nm$^{-1}$). Although the structural properties of this partially covalent liquid strongly deviate from a simple hard-sphere model, the dynamics, as reflected in the quasi-elastic scattering, are beautifully described within the framework of the extended heat mode approximation of Enskog's kinetic theory, analytically derived for a hard spheres system. The present work demonstrates the applicability of Enskog's theory to non hard- sphere and non simple liquids.Comment: 5 pages, 2 figures, accepted in Phys. Rev. Let

Tunneling of polarized fermions in 3D double wells

We study the tunneling of a spin polarized Fermi gas in a three-dimensional double well potential, focusing on the time dynamics starting from an initial state in which there is an imbalance in the number of particles in the two wells. Although fermions in different doublets of the double well tunnel with different frequencies, we point out that (incoherent) oscillations of a large number of particles can arise, as a consequence of the presence of transverse degrees of freedom. Estimates of the doublet structure and of the occupation of transverse eigenstates for a realistic experimental setup are provided.Comment: 10 pages, Typos corrected and figures changed - published in Laser Physics, issue on the LPHYS'11 conference (Sarajevo, 2011

A Constraint Solver for Flexible Protein Models

This paper proposes the formalization and implementation of a novel class of constraints aimed at modeling problems related to placement of multi-body systems in the 3-dimensional space. Each multi-body is a system composed of body elements, connected by joint relationships and constrained by geometric properties. The emphasis of this investigation is the use of multi-body systems to model native conformations of protein structures---where each body represents an entity of the protein (e.g., an amino acid, a small peptide) and the geometric constraints are related to the spatial properties of the composing atoms. The paper explores the use of the proposed class of constraints to support a variety of different structural analysis of proteins, such as loop modeling and structure prediction. The declarative nature of a constraint-based encoding provides elaboration tolerance and the ability to make use of any additional knowledge in the analysis studies. The filtering capabilities of the proposed constraints also allow to control the number of representative solutions that are withdrawn from the conformational space of the protein, by means of criteria driven by uniform distribution sampling principles. In this scenario it is possible to select the desired degree of precision and/or number of solutions. The filtering component automatically excludes configurations that violate the spatial and geometric properties of the composing multi-body system. The paper illustrates the implementation of a constraint solver based on the multi-body perspective and its empirical evaluation on protein structure analysis problems

Quantum Quenches in Integrable Field Theories

We study the non equilibrium time evolution of an integrable field theory in 1+1 dimensions after a sudden variation of a global parameter of the Hamiltonian. For a class of quenches defined in the text, we compute the long times limit of the one point function of a local operator as a series of form factors. Even if some subtleties force us to handle this result with care, there is a strong evidence that for long times the expectation value of any local operator can be described by a generalized Gibbs ensemble with a different effective temperature for each eigenmode

On the origin of the λ\lambda-transition in liquid Sulphur

Developing a novel experimental technique, we applied photon correlation spectroscopy using infrared radiation in liquid Sulphur around $T_\lambda$, i.e. in the temperature range where an abrupt increase in viscosity by four orders of magnitude is observed upon heating within few degrees. This allowed us - overcoming photo-induced and absorption effects at visible wavelengths - to reveal a chain relaxation process with characteristic time in the ms range. These results do rehabilitate the validity of the Maxwell relation in Sulphur from an apparent failure, allowing rationalizing the mechanical and thermodynamic behavior of this system within a viscoelastic scenario.Comment: 5 pages, 4 eps figures, accepted in Phys. Rev. Let

One-dimensional fermionic systems after interaction quenches and their description by bosonic field theories

We show that the dynamics of quenches in one dimension far off equilibrium can be described by power laws, but with exponents differing from the fully renormalized ones at lowest energies. Instead they depend on the initial state and its excitation energy. Furthermore, we found that for quenches to strong interactions unexpected similarities between systems in one and in infinite dimensions occur, indicating the dominance of local processes.Comment: This is a distinctly revised version which is focussed on the description of the dynamics by bosonization technique

a consensus statement for the clinical use of the renal sodium glucose co transporter 2 inhibitor dapagliflozin in patients with type 2 diabetes mellitus

ABSTRACTIntroduction: The present review developed a clinical consensus based on a Delphi method on Dapagliflozin, a selective inhibitor of the renal sodium-glucose co-transporter-2 (SGLT2-I) in the treatment of patients with Type 2 diabetes mellitus.Areas covered: Panel members, using a 5-point scale, were asked to rate 9 statements on pharmakodinamic, mode of action on glycaemic and extra-glycaemic effects, and safety of dapaglifozin, Members also aimed to identify the patient most susceptible to the treatment with dapagliflozin .Expert commentary: Dapagliflozin is effective in lowering the plasma glucose concentration with a good safety profile. Dapagliflozin can be utilized in combination with all other antihyperglycaemic agents at all stages of the disease: however, a reduced GFR limits its efficacy. As for the other drugs of the class, Dapagliflozin positively modifies other risk factors for CV disease: these effects will be tested in the so far largest cardiovascular outcome trial for the SGLT2 inh..