1,089 research outputs found
LegalHTML: semantic mark-up of legal acts using web technologies
We introduce here LegalHTML, an extension of the HTML language thought for representing legal acts. LegalHTML has been conceived in the context of an exploratory study conducted for the Publications Office of the European Union, with the objective of overcoming the proliferation of formats for the electronic redaction of legal acts, dedicated to different steps of the editorial process (e.g. first draft, content editing, proof reading, introducing semantics, publishing) and of realizing a model and a language that could bind all processes and exigencies under a common umbrella. LegalHTML satisfies these requirements by providing an explicit domain language addressing all structural aspects of an act, such as articles, paragraphs, items, references and an associated ontology (foreseeing both inline annotations through RDFa and explicit RDF code within script elements) providing rich semantics to describe the editorial and jurisdictional history of the act and to insert references to entities of the domain. Being based on HTML, presentation is also offered by the same language, an aspect missing from all most notable standards for the legal domain. Furthermore, LegalHTML addresses consolidation of an act and its subsequent modifications into a single document using a tree-based representation of the original content and of its modified versions. Finally, alongside the language & ontology, we implemented a CSS stylesheet for the default rendering of LegalHTML documents and a JavaScript file imbuing documents with an API supporting TOC generation, footnote cross-references and the said point-in-time visualization of consolidated legal acts
LIME: Towards a Metadata Module for Ontolex
The OntoLex W3C Community Group has been working for more than a year on realizing a proposal for a standard ontol-ogy lexicon model. As the core-specification of the model is almost com-plete, the group started development of additional modules for specific tasks and use cases. We think that in many usage scenarios (e.g. linguistic enrichment, lo-calization and alignment of ontologies) the discovery and exploitation of linguis-tically grounded datasets may benefit from summarizing information about their linguistic expressivity. While the VoID vocabulary covers the need for general metadata about linked datasets, this more specific information demands a dedicated extension. In this paper, we fill this gap by introducing LIME (Linguistic Metadata), a new vocabulary aiming at completing the OntoLex standard with specifications for linguistic metadata.
EXPERIMENTAL VALIDATION OF A CAPPILARY TUBE SIMULATION MODEL WITH REFRIGERANT MIXTURES FLOW
This paper presents the experimental validation of a simulation model for
refrigerant mixtures flow through capillary tubes. To perform such
validation it was built an experimental apparatus using a blow-down
process. It was carried out preliminary tests for characterization of
experimental parameters: actual capillary tube diameters; relative
roughness; and the heat losses in subcooling/quality control system. It
was obtained almost 200 experimental points for R-407C (a zeotropic
mixture) and R-410A (a near azeotropic mixture). Complete data set for
each point consists of the measured pressure and temperature profiles,
mass flow rate and mixture composition, as well as subcooling/quality
control system inlet and outlet temperatures and heater electric power
consumption for tests with two-phase flow capillary tube inlet conditions.
Comparison of simulation and experimental data show a good agreement.
Main deviations are connected with the delay of vaporization
phenomenon occurrence, experimentally verified by the authors
Negative-pressure pulmonary edema presented with concomitant spontaneous pneumomediastinum: Moore meets Macklin
Negative-pressure pulmonary edema is an unusual complication mainly associated with general anesthesia. It is caused by excessive negative intrathoracic pressure following a deep inspiration against an acute airway obstruction. The resultant decreased intrathoracic pressure amplifies venous return to the right heart and increases pulmonary capillary wedge pressure that can be further amplified by massive sympathetic discharge due to hypoxia. The combination of increased venous return and pulmonary capillary wedge pressure favours the shift of fluid into the pulmonary interstitium with resultant pulmonary edema. Conversely, spontaneous pneumomediastinum (SP) results from alveolar rupture following an excessive positive intrathoracic pressure. The air leaks out of the alveoli and along the perivascular space toward the mediastinum. We experienced a case of negative pulmonary edema which presented in association with SP. Pneumomediastinum is probably caused by an excessive positive intrathoracic pressure for a subsequent expiration against a closed airway. In the present case, both complications resolved with conservative management
FEASIBILITY OF A BRAYTON CYCLE AUTOMOTIVE AIR CONDITIONING SYSTEM
The goal of this work is to develop a preliminary analysis on the feasibility of using an alternative automotive air conditioning system based on the Brayton cycle, to be assembled using a turbocompression-intercooling system configuration available in the market. The first step of the analysis was a thermodynamic study to define the system capacity and parameters for selecting the system components. The next step was to select from turbocompressor maps a suitable model for the application, and to determine pressures/temperatures throughout the system in order to evaluate intercooler capacity and select a suitable model available in the market. The impact of the turbocompression system was also analyzed in engine performance. The proposed turbocompression system requires 1,7 kW from the engine, which is very similar to a conventional air conditioning system requirement. In terms of weight, this preliminary analysis indicated that the proposed system is about 1,0 kg heavier than the conventional system. The analysis indicated that the alternative system is about 56% more expensive than the conventional one, but on the other hand presents a 24% lower maintenance cost . Considering the results of the preliminary analysis, the proposed system is technically feasible for application in automotive air conditioning, but requires a design optimization process in order to reduce its weight and initial costs, which might allow lower maintenance costs to payback the alternative system
Reinforcement of wood with natural fibers
This paper describes an experimental programme which examines the reinforcement in flexure of timber beams with composite materials based on natural fibers in the form of fabrics made from hemp, flax, basalt and bamboo fibers. The industrial use of natural fibers has been continuously increasing since 1990s due to their advantages in terms of production costs, pollution emissions and energy consumption for production and disposal. The technique allows the reinforcement of the intrados of beams, avoiding the dismantling of the overlying part of the structure with significant savings in terms of costs and work time. The test program consists of three phases incorporating 45 beams. The bending tests on the wooden elements made it possible to measure the increase in capacity and stiffness resulting from the composite reinforcement. This was applied to beams, creating different arrangements and using different quantities (number of layers). Despite the diversity of the various tests carried out, the results obtained in some cases showed significant increases in terms of load-carrying capacity and in deflection ductility
Diagnostic and prognostic role of liquid biopsy in non-small cell lung cancer: evaluation of circulating biomarkers
Lung cancer is still one of the main causes of cancer-related death, together with prostate and colorectal
cancers in males and breast and colorectal cancers in females. The prognosis for non-small cell lung cancer
(NSCLC) is strictly dependent on feasibility of a complete surgical resection of the tumor at diagnosis. Since
surgery is indicated only in early stages tumors, it is necessary to anticipate the timing of diagnosis in clinical
practice. In the diagnostic and therapeutic pathway for NSCLC, sampling of neoplastic tissue is usually
obtained using invasive methods that are not free from disadvantages and complications. A valid alternative
to the standard biopsy is the liquid biopsy (LB), that is, the analysis of samples from peripheral blood, urine,
and other biological fluids, with a simple and non-invasive collection. In particular, it is possible to detect
in the blood different tumor derivatives, such as cell-free DNA (cfDNA) with its subtype circulating tumor
DNA (ctDNA), cell-free RNA (cfRNA), and circulating tumor cells (CTCs). Plasma-based testing seems to have
several advantages over tumor tissue biopsy; firstly, it reduces medical costs, risk of complications related
to invasive procedures, and turnaround times; moreover, the analysis of genes alteration, such as EGFR, ALK,
ROS1, and BRAF is faster and safer with this method, compared to tissue biopsy. Despite all these advantages,
the evidences in literatures indicate that assays performed on liquid biopsies have a low sensitivity, making
them unsuitable for screening in lung cancer at the current state. This is caused by lack of standardization
in sampling and preparation of specimen and by the low concentration of biomarkers in the bloodstream.
Instead, routinely use of LB should be preferred in revaluation of patients with advanced NSCLC resistant to
chemotherapy, due to onset of new mutations
A comparative analysis of Pancoast tumour resection performed via video-assisted thoracic surgery versus standard open approaches
OBJECTIVES: The aim of the present paper was to conduct a comparative analysis of outcomes after thoracoscopic resection versus standard
thoracotomy approach in the treatment of Pancoast tumours.
METHODS: All consecutive patients with Pancoast tumours undergoing surgical treatment from March 2000 to November 2012 were enrolled.
Patients were divided into 2 groups according to whether a thoracoscopic or standard thoracotomy approach was adopted. In addition
to morbidity and mortality, (i) intensity of pain; (ii) respiratory function focusing on the postoperative value and its variation with
respect to the predicted value (Delta); (iii) analgesic consumption at different times during the postoperative course; and (iiii) survival rate
were recorded in both groups and the inter-group differences were statistically compared.
RESULTS: Of the 45 enrolled patients, 34 (75%) were included in the final analysis (18 in the thoracoscopic group and 16 in the standard
group). Eleven (25%) patients were excluded because they (i) were unfit for surgery after induction therapy (n = 4); (ii) refused the operation
(n = 1) or (iii) had unexpected pleural involvement (n = 6). Compared with the standard group, in the thoracoscopic group we observed
less pain (P = 0.01), better recovery of forced vital capacity (P = 0.01) and forced expiratory value in 1 s (P < 0.001), and a reduction in
opioid (P = 0.01) and analgesic consumption (P = 0.02). The median survival for all patients was 15 months. Patients with N0/N1 disease
had better median survival than N2 patients (47 vs 9 months; P = 0.009). One local recurrence in the standard group was observed 1 year
after operation, whereas 2 local recurrences, 1 in the thoracoscopic group and another in the standard group, were registered 2 years after
the operation (P = 1.0). Finally, 4 (22%) extrathoracic metastases in the thoracoscopic group and 5 (31%) in the standard group (P = 0.8)
were found over the 2 years following the procedure.
CONCLUSIONS: In the management of Pancoast tumours, a thoracoscopic approach is safe and may be an effective adjunct to standard
surgical resection in selected cases. Such an approach enabled surgeons to explore the pleural cavity and avoid exploratory thoracotomy
in cases of unexpected pleural involvement
Atributos agronômicos do milho sob diferentes manejos de solo e sucessões de cultura no Sudoeste Amazônico.
O objetivo deste trabalho foi avaliar a produtividade e outros atributos agronômicos da cultura do milho sob sistemas de sucessão de culturas e diferentes manejos de solo na região sudoeste da Amazônia; o experimento foi instalado em um Latossolo Vermelho-Amarelo, na fazenda experimental da Universidade Federal de Rondônia - UNIR.Organizado por: Henrique Nery Cipriani; Alaerto Luiz Marcolan; Fernando Machado Pfeifer: Alexandre Martins Abdão dos Passos; Marcelo Curitiba Espíndula; Angelo Mansur Mendes
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